ICP0 and the US3 protein kinase of herpes simplex virus 1 independently block histone deacetylation to enable gene expression.
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ICP0 antagonizes ICP4-dependent silencing of the herpes simplex virus ICP0 geneMapping of key functions of the herpes simplex virus 1 U(S)3 protein kinase: the U(S)3 protein can form functional heteromultimeric structures derived from overlapping truncated polypeptidesHSV-1 tegument protein and the development of its genome editing technologyBovine Herpes Virus 1 (BHV-1) and Herpes Simplex Virus Type 1 (HSV-1) Promote Survival of Latently Infected Sensory Neurons, in Part by Inhibiting ApoptosisOcular herpes simplex virus: how are latency, reactivation, recurrent disease and therapy interrelated?A viral E3 ligase targets RNF8 and RNF168 to control histone ubiquitination and DNA damage responsesHuman cytomegalovirus UL29/28 protein interacts with components of the NuRD complex which promote accumulation of immediate-early RNAThe varicella-zoster virus immediate-early 63 protein affects chromatin-controlled gene transcription in a cell-type dependent mannerTranscriptomic analysis of the dialogue between Pseudorabies virus and porcine epithelial cells during infectionRole of chromatin during herpesvirus infections.Towards an understanding of the herpes simplex virus type 1 latency-reactivation cycleICP0 inhibits the decrease of HSV amplicon-mediated transgene expression.Herpes simplex virus protein kinases US3 and UL13 modulate VP11/12 phosphorylation, virion packaging, and phosphatidylinositol 3-kinase/Akt signaling activityChanges to euchromatin on LAT and ICP4 following reactivation are more prevalent in an efficiently reactivating strain of HSV-1.Role of herpes simplex virus ICP0 in the transactivation of genes introduced by infection or transfection: a reappraisal.Herpes simplex virus 1 protein kinase US3 hyperphosphorylates p65/RelA and dampens NF-κB activation.Dengue virus capsid protein binds core histones and inhibits nucleosome formation in human liver cells.Viral-encoded enzymes that target host chromatin functions.Disruption of HDAC/CoREST/REST repressor by dnREST reduces genome silencing and increases virulence of herpes simplex virusCircadian CLOCK histone acetyl transferase localizes at ND10 nuclear bodies and enables herpes simplex virus gene expressionConstitutive mTORC1 activation by a herpesvirus Akt surrogate stimulates mRNA translation and viral replicationThe CoREST/REST repressor is both necessary and inimical for expression of herpes simplex virus genes.Herpes simplex virus ICP0 promotes both histone removal and acetylation on viral DNA during lytic infection.Us3 kinase encoded by herpes simplex virus 1 mediates downregulation of cell surface major histocompatibility complex class I and evasion of CD8+ T cellsThe differential mobilization of histones H3.1 and H3.3 by herpes simplex virus 1 relates histone dynamics to the assembly of viral chromatinA novel oncolytic herpes simplex virus that synergizes with phosphoinositide 3-kinase/Akt pathway inhibitors to target glioblastoma stem cells.The checkpoints of viral gene expression in productive and latent infection: the role of the HDAC/CoREST/LSD1/REST repressor complexBarrier to auto integration factor becomes dephosphorylated during HSV-1 Infection and Can Act as a host defense by impairing viral DNA replication and gene expressionHerpes simplex virus 1 protein kinase Us3 and major tegument protein UL47 reciprocally regulate their subcellular localization in infected cells.Diversity and evolution of chromatin proteins encoded by DNA viruses.The UL13 and US3 Protein Kinases of Herpes Simplex Virus 1 Cooperate to Promote the Assembly and Release of Mature, Infectious Virions.The Us3 Protein of Herpes Simplex Virus 1 Inhibits T Cell Signaling by Confining Linker for Activation of T Cells (LAT) Activation via TRAF6 Protein.In transduced cells, the US3 protein kinase of herpes simplex virus 1 precludes activation and induction of apoptosis by transfected procaspase 3.Characterization of a Herpes Simplex Virus 1 (HSV-1) Chimera in Which the Us3 Protein Kinase Gene Is Replaced with the HSV-2 Us3 Gene.Human cytomegalovirus UL97 kinase activity is required for the hyperphosphorylation of retinoblastoma protein and inhibits the formation of nuclear aggresomes.Expression of gamma interferon-dependent genes is blocked independently by virion host shutoff RNase and by US3 protein kinaseEnzymatically inactive U(S)3 protein kinase of Marek's disease virus (MDV) is capable of depolymerizing F-actin but results in accumulation of virions in perinuclear invaginations and reduced virus growth.Cdc34p ubiquitin-conjugating enzyme is a component of the tombusvirus replicase complex and ubiquitinates p33 replication proteinQuantitative whole-cell proteome analysis of pseudorabies virus-infected cellsHuman cytomegalovirus pUL97 regulates the viral major immediate early promoter by phosphorylation-mediated disruption of histone deacetylase 1 binding.
P2860
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P2860
ICP0 and the US3 protein kinase of herpes simplex virus 1 independently block histone deacetylation to enable gene expression.
description
2006 nî lūn-bûn
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2006 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
ICP0 and the US3 protein kinas ...... ion to enable gene expression.
@ast
ICP0 and the US3 protein kinas ...... ion to enable gene expression.
@en
ICP0 and the US3 protein kinas ...... ion to enable gene expression.
@nl
type
label
ICP0 and the US3 protein kinas ...... ion to enable gene expression.
@ast
ICP0 and the US3 protein kinas ...... ion to enable gene expression.
@en
ICP0 and the US3 protein kinas ...... ion to enable gene expression.
@nl
prefLabel
ICP0 and the US3 protein kinas ...... ion to enable gene expression.
@ast
ICP0 and the US3 protein kinas ...... ion to enable gene expression.
@en
ICP0 and the US3 protein kinas ...... ion to enable gene expression.
@nl
P2860
P356
P1476
ICP0 and the US3 protein kinas ...... ion to enable gene expression.
@en
P2093
Alice P W Poon
Haidong Gu
P2860
P304
P356
10.1073/PNAS.0604142103
P407
P577
2006-06-19T00:00:00Z