DNA ligase III is recruited to DNA strand breaks by a zinc finger motif homologous to that of poly(ADP-ribose) polymerase. Identification of two functionally distinct DNA binding regions within DNA ligase III.

DNA ligase III is recruited to DNA strand breaks by a zinc finger motif homologous to that of poly(ADP-ribose) polymerase. Identification of two functionally distinct DNA binding regions within DNA ligase III.

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http://www.wikidata.org/entity/Q33869047

Q33869047

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Structural and mechanistic conservation in DNA ligases Crucial role for DNA ligase III in mitochondria but not in Xrcc1-dependent repair Distinct kinetics of human DNA ligases I, IIIalpha, IIIbeta, and IV reveal direct DNA sensing ability and differential physiological functions in DNA repair DNA ligase III: a spotty presence in eukaryotes, but an essential function where tested Kinetic mechanism of human DNA ligase I reveals magnesium-dependent changes in the rate-limiting step that compromise ligation efficiency Eukaryotic DNA ligases: structural and functional insights Partial complementation of a DNA ligase I deficiency by DNA ligase III and its impact on cell survival and telomere stability in mammalian cells Human DNA ligase III recognizes DNA ends by dynamic switching between two DNA-bound states Two DNA-binding and nick recognition modules in human DNA ligase III Molecular mechanism of DNA deadenylation by the neurological disease protein aprataxin Physical and functional interaction between DNA ligase IIIalpha and poly(ADP-Ribose) polymerase 1 in DNA single-strand break repair ATP-dependent DNA ligases The role of the Zn(II) binding domain in the mechanism of E. coli DNA topoisomerase I Crystal structure of NAD+-dependent DNA ligase: modular architecture and functional implications Crystal Structures of Poly(ADP-ribose) Polymerase-1 (PARP-1) Zinc Fingers Bound to DNA: STRUCTURAL AND FUNCTIONAL INSIGHTS INTO DNA-DEPENDENT PARP-1 ACTIVITY The DNA-Binding Domain of Human PARP-1 Interacts with DNA Single-Strand Breaks as a Monomer through Its Second Zinc Finger Interactions of the DNA ligase IV-XRCC4 complex with DNA ends and the DNA-dependent protein kinase DNA ligases I and III cooperate in alternative non-homologous end-joining in vertebrates Early embryonic lethality due to targeted inactivation of DNA ligase III Recruitment of DNA methyltransferase I to DNA repair sites Differential recruitment of DNA Ligase I and III to DNA repair sites.Feedback-regulated poly(ADP-ribosyl)ation by PARP-1 is required for rapid response to DNA damage in living cells Sensing DNA damage by PARP-like fingers.Structure and function of the DNA ligases encoded by the mammalian LIG3 gene.DNA ligases as therapeutic targets Structure-function analysis of the OB and latch domains of chlorella virus DNA ligase.DNA ligase III acts as a DNA strand break sensor in the cellular orchestration of DNA strand break repair ATM mediates oxidative stress-induced dephosphorylation of DNA ligase IIIalpha.Human Mre11/human Rad50/Nbs1 and DNA ligase IIIalpha/XRCC1 protein complexes act together in an alternative nonhomologous end joining pathway Human DNA ligase III bridges two DNA ends to promote specific intermolecular DNA end joining Inhibition of Poly(ADP-Ribose) Polymerase Enhances Radiochemosensitivity in Cancers Proficient in DNA Double-Strand Break Repair Human DNA ligases I and III, but not ligase IV, are required for microhomology-mediated end joining of DNA double-strand breaks.Structural recognition of DNA by poly(ADP-ribose)polymerase-like zinc finger families.SCR7 is neither a selective nor a potent inhibitor of human DNA ligase IV Identification and validation of human DNA ligase inhibitors using computer-aided drug design.PARP-1 mechanism for coupling DNA damage detection to poly(ADP-ribose) synthesis.Conformational transitions of proteins engaged in DNA double-strand break repair, analysed by tryptophan fluorescence emission and FRET.Characterization of an ATP-dependent DNA ligase from the thermophilic archaeon Methanobacterium thermoautotrophicum.Development of thermotolerance requires interaction between polymerase-beta and heat shock proteins.A novel interaction between DNA ligase III and DNA polymerase gamma plays an essential role in mitochondrial DNA stability.

P2860

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P2860

DNA ligase III is recruited to DNA strand breaks by a zinc finger motif homologous to that of poly(ADP-ribose) polymerase. Identification of two functionally distinct DNA binding regions within DNA ligase III.

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http://www.wikidata.org/entity/Q33869047

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1999 nî lūn-bûn

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1999 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

1999 թվականի հուլիսին հրատարակված գիտական հոդված

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1999年の論文

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1999年論文

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1999年論文

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1999年論文

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1999年論文

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1999年論文

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1999年论文

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