Role of SHPS-1 in the regulation of insulin-like growth factor I-stimulated Shc and mitogen-activated protein kinase activation in vascular smooth muscle cells.
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Cooperation between integrin alphavbeta3 and VEGFR2 in angiogenesisIdentification of compounds that inhibit IGF-I signaling in hyperglycemia.Glucose-oxidized low-density lipoproteins enhance insulin-like growth factor I-stimulated smooth muscle cell proliferation by inhibiting integrin-associated protein cleavageThe role of Src homology 2 containing protein tyrosine phosphatase 2 in vascular smooth muscle cell migration and proliferation.Prolactin enhances insulin-like growth factor I receptor phosphorylation by decreasing its association with the tyrosine phosphatase SHP-2 in MCF-7 breast cancer cells.p66shc inhibits insulin-like growth factor-I signaling via direct binding to Src through its polyproline and Src homology 2 domains, resulting in impairment of Src kinase activation.Insulin-like growth factor-I-stimulated insulin receptor substrate-1 negatively regulates Src homology 2 domain-containing protein-tyrosine phosphatase substrate-1 function in vascular smooth muscle cells.AMP-activated protein kinase inhibits IGF-I signaling and protein synthesis in vascular smooth muscle cells via stimulation of insulin receptor substrate 1 S794 and tuberous sclerosis 2 S1345 phosphorylation.Impact of MUC1 mucin downregulation in the phenotypic characteristics of MKN45 gastric carcinoma cell linePDK1 recruitment to the SHPS-1 signaling complex enhances insulin-like growth factor-i-stimulated AKT activation and vascular smooth muscle cell survival.Hyperglycemia-induced p66shc inhibits insulin-like growth factor I-dependent cell survival via impairment of Src kinase-mediated phosphoinositide-3 kinase/AKT activation in vascular smooth muscle cells.The role of cis dimerization of signal regulatory protein alpha (SIRPalpha) in binding to CD47Blocking ligand occupancy of the αVβ3 integrin inhibits the development of nephropathy in diabetic pigsDifferential signaling by adaptor molecules LRP1 and ShcA regulates adipogenesis by the insulin-like growth factor-1 receptorIGF-I stimulates cooperative interaction between the IGF-I receptor and CSK homologous kinase that regulates SHPS-1 phosphorylation in vascular smooth muscle cells.Hyperglycemia enhances IGF-I-stimulated Src activation via increasing Nox4-derived reactive oxygen species in a PKCζ-dependent manner in vascular smooth muscle cells.An essential role for the association of CD47 to SHPS-1 in skeletal remodeling.Insulin-like growth factor (IGF) binding protein 2 functions coordinately with receptor protein tyrosine phosphatase β and the IGF-I receptor to regulate IGF-I-stimulated signaling.Insulin-like growth factor (IGF) signaling requires αvβ3-IGF1-IGF type 1 receptor (IGF1R) ternary complex formation in anchorage independence, and the complex formation does not require IGF1R and Src activationGlucose regulation of integrin-associated protein cleavage controls the response of vascular smooth muscle cells to insulin-like growth factor-I.Insulin-like growth factor-I stimulates Shc-dependent phosphatidylinositol 3-kinase activation via Grb2-associated p85 in vascular smooth muscle cellsRole of the integrin alphaVbeta3 in mediating increased smooth muscle cell responsiveness to IGF-I in response to hyperglycemic stress.Recruitment of Nox4 to a plasma membrane scaffold is required for localized reactive oxygen species generation and sustained Src activation in response to insulin-like growth factor-I.Integrin-associated protein association with SRC homology 2 domain containing tyrosine phosphatase substrate 1 regulates igf-I signaling in vivop66shc negatively regulates insulin-like growth factor I signal transduction via inhibition of p52shc binding to Src homology 2 domain-containing protein tyrosine phosphatase substrate-1 leading to impaired growth factor receptor-bound protein-2 memSIRPA is a specific cell-surface marker for isolating cardiomyocytes derived from human pluripotent stem cells.Identification of novel SHPS-1-associated proteins and their roles in regulation of insulin-like growth factor-dependent responses in vascular smooth muscle cells.Role of IGF-1 in glucose regulation and cardiovascular disease.Androgen receptor-mediated non-genomic regulation of prostate cancer cell proliferationGlucose regulation of thrombospondin and its role in the modulation of smooth muscle cell proliferationIGF-1 regulation of key signaling pathways in bone.Dual regulation of SIRPalpha phosphorylation by integrins and CD47.A novel antioxidant peptide derived from wheat germ prevents high glucose-induced oxidative stress in vascular smooth muscle cells in vitro.The role of Src kinase in insulin-like growth factor-dependent mitogenic signaling in vascular smooth muscle cells.
P2860
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P2860
Role of SHPS-1 in the regulation of insulin-like growth factor I-stimulated Shc and mitogen-activated protein kinase activation in vascular smooth muscle cells.
description
2005 nî lūn-bûn
@nan
2005 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Role of SHPS-1 in the regulati ...... vascular smooth muscle cells.
@ast
Role of SHPS-1 in the regulati ...... vascular smooth muscle cells.
@en
type
label
Role of SHPS-1 in the regulati ...... vascular smooth muscle cells.
@ast
Role of SHPS-1 in the regulati ...... vascular smooth muscle cells.
@en
prefLabel
Role of SHPS-1 in the regulati ...... vascular smooth muscle cells.
@ast
Role of SHPS-1 in the regulati ...... vascular smooth muscle cells.
@en
P2093
P2860
P356
P1476
Role of SHPS-1 in the regulati ...... vascular smooth muscle cells.
@en
P2093
David R Clemmons
Jane Badley-Clarke
Jaroslava Lieskovska
Laura A Maile
P2860
P304
P356
10.1091/MBC.E04-10-0918
P577
2005-05-11T00:00:00Z