Sigma receptors: recent advances and new clinical potentials.
about
Methylphenidate enhances NMDA-receptor response in medial prefrontal cortex via sigma-1 receptor: a novel mechanism for methylphenidate actionAntagonist action of progesterone at σ-receptors in the modulation of voltage-gated sodium channelsRole of sigma receptors in methamphetamine-induced neurotoxicityRole of sigma-1 receptor C-terminal segment in inositol 1,4,5-trisphosphate receptor activation: constitutive enhancement of calcium signaling in MCF-7 tumor cellsGeneration and phenotypic analysis of sigma receptor type I (sigma 1) knockout miceSigma receptors: from discovery to highlights of their implications in the cardiovascular systemAC927, a σ receptor ligand, blocks methamphetamine-induced release of dopamine and generation of reactive oxygen species in NG108-15 cells4-aroylpiperidines and 4-(α-hydroxyphenyl)piperidines as selective sigma-1 receptor ligands: synthesis, preliminary pharmacological evaluation and computational studiesSigma-1 receptors regulate Bcl-2 expression by reactive oxygen species-dependent transcriptional regulation of nuclear factor kappaBSigma 1 receptor modulation of G-protein-coupled receptor signaling: potentiation of opioid transduction independent from receptor binding.Detergent-resistant microdomains determine the localization of sigma-1 receptors to the endoplasmic reticulum-mitochondria junction.The σ2 receptor: a novel protein for the imaging and treatment of cancer.Early development of sigma-receptor ligands.Sigma-2 receptor ligands and their perspectives in cancer diagnosis and therapy.An update on the development of drugs for neuropsychiatric disorders: focusing on the sigma 1 receptor ligand.Synthesis and in vitro biological evaluation of carbonyl group-containing analogues for σ1 receptors.Sigma-1 receptor chaperones and diseases4-IBP, a sigma1 receptor agonist, decreases the migration of human cancer cells, including glioblastoma cells, in vitro and sensitizes them in vitro and in vivo to cytotoxic insults of proapoptotic and proautophagic drugsSynthesis of N-phenyl-N-(3-(piperidin-1-yl)propyl)benzofuran-2-carboxamides as new selective ligands for sigma receptorsThe lifetime of UDP-galactose:ceramide galactosyltransferase is controlled by a distinct endoplasmic reticulum-associated degradation (ERAD) regulated by sigma-1 receptor chaperonesCM156, a high affinity sigma ligand, attenuates the stimulant and neurotoxic effects of methamphetamine in miceFrom α4β2 Nicotinic Ligands to the Discovery of σ1 Receptor Ligands: Pharmacophore Analysis and Rational Design.Sigma receptors [σRs]: biology in normal and diseased statesAnalysis of sigma receptor (sigmaR1) expression in retinal ganglion cells cultured under hyperglycemic conditions and in diabetic mice.Pharmacology and therapeutic potential of sigma(1) receptor ligands.Small molecule modulator of sigma 2 receptor is neuroprotective and reduces cognitive deficits and neuroinflammation in experimental models of Alzheimer's disease.Neuroprotective targets through which 6-acetyl-3-(4-(4-(4-fluorophenyl)piperazin-1-yl)butyl)benzo[d]oxazol-2(3H)-one (SN79), a sigma receptor ligand, mitigates the effects of methamphetamine in vitro.Sigma receptors and their ligands in cancer biology: overview and new perspectives for cancer therapy.Therapeutic targeting of pancreatic cancer utilizing sigma-2 ligands.How toxic is ibogaine?Targeting Nanocarriers with Anisamide: Fact or Artifact?Progesterone receptor membrane component 1/Sigma-2 receptor associates with MAP1LC3B and promotes autophagy.Juxtaposition of the steroid binding domain-like I and II regions constitutes a ligand binding site in the sigma-1 receptor.Inhibitory effects of sigma-2 receptor agonists on T lymphocyte activation.Isolation and characterization of alternatively spliced variants of the mouse sigma1 receptor gene, Sigmar1.Synthesis and evaluation of [18F]fluoroethyl SA4503 as a PET ligand for the sigma receptor.Evidence for sigma-1-like receptors in isolated rat liver mitochondrial membranes.The sigma-1 receptor modulates NMDA receptor synaptic transmission and plasticity via SK channels in rat hippocampus.[3H]BHDP as a novel and selective ligand for sigma1 receptors in liver mitochondria and brain synaptosomes of the rat.Synthesis and in vitro evaluation of tetrahydroisoquinolines with pendent aromatics as sigma-2 (σ2) selective ligands.
P2860
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P2860
Sigma receptors: recent advances and new clinical potentials.
description
2000 nî lūn-bûn
@nan
2000 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի մարտին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Sigma receptors: recent advances and new clinical potentials.
@ast
Sigma receptors: recent advances and new clinical potentials.
@en
type
label
Sigma receptors: recent advances and new clinical potentials.
@ast
Sigma receptors: recent advances and new clinical potentials.
@en
prefLabel
Sigma receptors: recent advances and new clinical potentials.
@ast
Sigma receptors: recent advances and new clinical potentials.
@en
P1476
Sigma receptors: recent advances and new clinical potentials.
@en
P2093
P304
P356
10.1016/S0031-6865(99)00034-5
P577
2000-03-01T00:00:00Z