Inhibition of NAD(P)H:quinone oxidoreductase 1 activity and induction of p53 degradation by the natural phenolic compound curcumin.
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Curcumin and tumor immune-editing: resurrecting the immune systemAn NQO1-initiated and p53-independent apoptotic pathway determines the anti-tumor effect of tanshinone IIA against non-small cell lung cancerUnravelling the Structural and Molecular Basis Responsible for the Anti-Biofilm Activity of Zosteric AcidNAD(P)H: quinone oxidoreductase 1 deficiency conjoint with marginal vitamin C deficiency causes cigarette smoke induced myelodysplastic syndromes.Combination of metformin and curcumin targets breast cancer in mice by angiogenesis inhibition, immune system modulation and induction of p53 independent apoptosis.The anticancer effects of actinoporin RTX-A from the sea anemone Heteractis crispa (=Radianthus macrodactylus)Thioredoxin reductase is irreversibly modified by curcumin: a novel molecular mechanism for its anticancer activity.Putative cancer chemopreventive agents of dietary origin-how safe are they?Colorectal cancer: chemopreventive role of curcumin and resveratrol.Resveratrol potentiates the in vitro and in vivo anti-tumoral effects of curcumin in head and neck carcinomasUbiquitin and ubiquitin-like modifications of the p53 family.Curcumin mitigates accelerated aging after irradiation in Drosophila by reducing oxidative stress.Long term effect of curcumin in restoration of tumour suppressor p53 and phase-II antioxidant enzymes via activation of Nrf2 signalling and modulation of inflammation in prevention of cancer.NQO1 Stabilizes p53 in Response to Oncogene-Induced Senescence.Curcumin inhibits protein phosphatases 2A and 5, leading to activation of mitogen-activated protein kinases and death in tumor cells.Inhibition of estrogen signaling activates the NRF2 pathway in breast cancer.Inhibitory effects of meju prepared with mixed starter cultures on azoxymethane and dextran sulfate sodium-induced colon carcinogenesis in mice.Phase I and Phase II enzyme polymorphisms and childhood cancer.Curcumin inhibits HIV-1 by promoting Tat protein degradation.Natural and synthetic quinones and their reduction by the quinone reductase enzyme NQO1: from synthetic organic chemistry to compounds with anticancer potential.Curcumin and cancer cells: how many ways can curry kill tumor cells selectively?The targets of curcumin.Curcumin Monoglucoside Shows Improved Bioavailability and Mitigates Rotenone Induced Neurotoxicity in Cell and Drosophila Models of Parkinson's Disease.Curcumin and Its Role in Chronic Diseases.Syntheses and cytotoxic properties of the curcumin analogs 2,6-bis(benzylidene)-4-phenylcyclohexanones.The two common polymorphic forms of human NRH-quinone oxidoreductase 2 (NQO2) have different biochemical properties.E3 ligase STUB1/CHIP regulates NAD(P)H:quinone oxidoreductase 1 (NQO1) accumulation in aged brain, a process impaired in certain Alzheimer disease patients.Susceptibility of p53 unstructured N terminus to 20 S proteasomal degradation programs the stress response.In vivo MRSI of hyperpolarized [1-(13)C]pyruvate metabolism in rat hepatocellular carcinoma.Curcumin inhibits hepatitis B virus via down-regulation of the metabolic coactivator PGC-1alpha.Apigenin induced MCF-7 cell apoptosis-associated reactive oxygen species.Coupling to a cancer cell-specific antibody potentiates tumoricidal properties of curcumin.Curcumin targets multiple enzymes involved in the ROS metabolic pathway to suppress tumor cell growth.Chemopreventive effect of dietary curcumin on inflammation-induced colorectal carcinogenesis in mice.Genetic deletion of NAD(P)H:quinone oxidoreductase 1 abrogates activation of nuclear factor-kappaB, IkappaBalpha kinase, c-Jun N-terminal kinase, Akt, p38, and p44/42 mitogen-activated protein kinases and potentiates apoptosis.Effect of β-Eudesmol on NQO1 suppression-enhanced sensitivity of cholangiocarcinoma cells to chemotherapeutic agents.
P2860
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P2860
Inhibition of NAD(P)H:quinone oxidoreductase 1 activity and induction of p53 degradation by the natural phenolic compound curcumin.
description
2005 nî lūn-bûn
@nan
2005 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Inhibition of NAD(P)H:quinone ...... al phenolic compound curcumin.
@ast
Inhibition of NAD(P)H:quinone ...... al phenolic compound curcumin.
@en
type
label
Inhibition of NAD(P)H:quinone ...... al phenolic compound curcumin.
@ast
Inhibition of NAD(P)H:quinone ...... al phenolic compound curcumin.
@en
prefLabel
Inhibition of NAD(P)H:quinone ...... al phenolic compound curcumin.
@ast
Inhibition of NAD(P)H:quinone ...... al phenolic compound curcumin.
@en
P2093
P2860
P356
P1476
Inhibition of NAD(P)H:quinone ...... ral phenolic compound curcumin
@en
P2093
Joseph Lotem
Veronica Reiss
Yosef Shaul
P2860
P304
P356
10.1073/PNAS.0501828102
P407
P577
2005-04-04T00:00:00Z