Cancer cells metabolically "fertilize" the tumor microenvironment with hydrogen peroxide, driving the Warburg effect: implications for PET imaging of human tumors - Wikidata - wikimedia - TriplyDB

Cancer cells metabolically "fertilize" the tumor microenvironment with hydrogen peroxide, driving the Warburg effect: implications for PET imaging of human tumors

Cancer cells metabolically "fertilize" the tumor microenvironment with hydrogen peroxide, driving the Warburg effect: implications for PET imaging of human tumors

http://www.wikidata.org/entity/Q33967878

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Links between metabolism and cancer Paradigm Shift in Radiation Biology/Radiation Oncology-Exploitation of the "H₂O₂ Effect" for Radiotherapy Using Low-LET (Linear Energy Transfer) Radiation such as X-rays and High-Energy Electrons Cilia in autophagy and cancer Prognostic Indications of Elevated MCT4 and CD147 across Cancer Types: A Meta-Analysis Oncogenes induce the cancer-associated fibroblast phenotype: metabolic symbiosis and "fibroblast addiction" are new therapeutic targets for drug discovery Anti-angiogenesis and metastasis: a tumour and stromal cell alliance Role of oxidative stress and the microenvironment in breast cancer development and progression Autophagy and cancer cell metabolism On metabolic reprogramming and tumor biology: A comprehensive survey of metabolism in breast cancer The Warburg effect: 80 years on Cancer: An Oxidative Crosstalk between Solid Tumor Cells and Cancer Associated Fibroblasts Dynamic self-guiding analysis of Alzheimer's disease.Constructing de novo H2O2 signaling via induced protein proximity Oxidative DNA damage caused by inflammation may link to stress-induced non-targeted effects.Personalising and targeting antiangiogenic resistance: a complex and multifactorial approach.Endoplasmic reticulum stress and oxidative stress in cell fate decision and human disease.Fibroblast heterogeneity in the cancer wound.High glucose promotes pancreatic cancer cell proliferation via the induction of EGF expression and transactivation of EGFR Sodium dichloroacetate exhibits anti-leukemic activity in B-chronic lymphocytic leukemia (B-CLL) and synergizes with the p53 activator Nutlin-3.Systemic DNA damage accumulation under in vivo tumor growth can be inhibited by the antioxidant Tempol Chemical mapping of the colorectal cancer microenvironment via MALDI imaging mass spectrometry (MALDI-MSI) reveals novel cancer-associated field effects Tumor-stroma metabolic relationship based on lactate shuttle can sustain prostate cancer progression Metabolic phenotypes in pancreatic cancer.Peroxisome proliferator-activated receptor-α staining is associated with worse outcome in colorectal liver metastases.Hydrogen peroxide fuels aging, inflammation, cancer metabolism and metastasis: the seed and soil also needs "fertilizer".Understanding the metabolic basis of drug resistance: therapeutic induction of the Warburg effect kills cancer cells.The role of autophagy induced by tumor microenvironment in different cells and stages of cancer Hypoxia Up-Regulates Galectin-3 in Mammary Tumor Progression and Metastasis.Mitochondrial oxidative stress in cancer-associated fibroblasts drives lactate production, promoting breast cancer tumor growth: understanding the aging and cancer connection Is cancer a metabolic rebellion against host aging? In the quest for immortality, tumor cells try to save themselves by boosting mitochondrial metabolism Tumor microenvironment promotes dicarboxylic acid carrier-mediated transport of succinate to fuel prostate cancer mitochondria Using the "reverse Warburg effect" to identify high-risk breast cancer patients: stromal MCT4 predicts poor clinical outcome in triple-negative breast cancers.Mitochondrial metabolism in cancer metastasis: visualizing tumor cell mitochondria and the "reverse Warburg effect" in positive lymph node tissue.Gene expression signatures of breast cancer stem and progenitor cells do not exhibit features of Warburg metabolism.An Oncogenic Virus Promotes Cell Survival and Cellular Transformation by Suppressing Glycolysis Autophagy and senescence in cancer-associated fibroblasts metabolically supports tumor growth and metastasis via glycolysis and ketone production Two-compartment tumor metabolism: autophagy in the tumor microenvironment and oxidative mitochondrial metabolism (OXPHOS) in cancer cells The study of energy metabolism in bladder cancer cells in co-culture conditions using a microfluidic chip.Oxidized ATM promotes abnormal proliferation of breast CAFs through maintaining intracellular redox homeostasis and activating the PI3K-AKT, MEK-ERK, and Wnt-β-catenin signaling pathways.CDK inhibitors (p16/p19/p21) induce senescence and autophagy in cancer-associated fibroblasts, "fueling" tumor growth via paracrine interactions, without an increase in neo-angiogenesis.

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Cancer cells metabolically "fertilize" the tumor microenvironment with hydrogen peroxide, driving the Warburg effect: implications for PET imaging of human tumors

http://www.wikidata.org/entity/Q33967878

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2011 nî lūn-bûn

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2011 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի օգոստոսին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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Cancer cells metabolically "fe ...... or PET imaging of human tumors

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Anthony Howell

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Casey Trimmer

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Chenguang Wang

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Neal Flomenberg

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Richard G Pestell

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Stephanos Pavlides

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Ubaldo E Martinez-Outschoorn

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Zhao Lin

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P2860

Transcriptional evidence for the "Reverse Warburg Effect" in human breast cancer tumor stroma and metastasis: similarities with oxidative stress, inflammation, Alzheimer's disease, and "Neuron-Glia Metabolic Coupling"

Autophagy in cancer associated fibroblasts promotes tumor cell survival: Role of hypoxia, HIF1 induction and NFκB activation in the tumor stromal microenvironment

The autophagic tumor stroma model of cancer: Role of oxidative stress and ketone production in fueling tumor cell metabolism

Oxidative stress in cancer associated fibroblasts drives tumor-stroma co-evolution: A new paradigm for understanding tumor metabolism, the field effect and genomic instability in cancer cells

Understanding the "lethal" drivers of tumor-stroma co-evolution: emerging role(s) for hypoxia, oxidative stress and autophagy/mitophagy in the tumor micro-environment

Loss of stromal caveolin-1 expression predicts poor clinical outcome in triple negative and basal-like breast cancers

A tissue-scale gradient of hydrogen peroxide mediates rapid wound detection in zebrafish.

Stromal cell expression of caveolin-1 predicts outcome in breast cancer

An absence of stromal caveolin-1 expression predicts early tumor recurrence and poor clinical outcome in human breast cancers

Quis custodiet ipsos custodies: who watches the watchmen?

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2504-2520

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scholarly article

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10.4161/CC.10.15.16585

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15

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10

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Michael P. Lisanti

Federica Sotgia

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2011-08-01T00:00:00Z

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51511317

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21778829

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3180189

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