Sodium dichloroacetate exhibits anti-leukemic activity in B-chronic lymphocytic leukemia (B-CLL) and synergizes with the p53 activator Nutlin-3.
about
MDM2/X inhibitors under clinical evaluation: perspectives for the management of hematological malignancies and pediatric cancer.The anti-leukemic activity of sodium dichloroacetate in p53mutated/null cells is mediated by a p53-independent ILF3/p21 pathwayThe presence of wild type p53 in hematological cancers improves the efficacy of combinational therapy targeting metabolismIbrutinib synergizes with MDM-2 inhibitors in promoting cytotoxicity in B chronic lymphocytic leukemia.Metformin combined with sodium dichloroacetate promotes B leukemic cell death by suppressing anti-apoptotic protein Mcl-1.Dichloroacetate, a selective mitochondria-targeting drug for oral squamous cell carcinoma: a metabolic perspective of treatment.Changes in metabolism affect expression of ABC transporters through ERK5 and depending on p53 status.The effect of dichloroacetate on male rat thymus and on thymocyte cell cycle.Targeting Mitochondrial Bioenergetics as a Therapeutic Strategy for Chronic Lymphocytic Leukemia.
P2860
Q33869257-04C60503-CC9F-4F07-9FA2-47B60C375B05Q35273665-60EF98A4-40A0-471E-8194-B0AE438914C3Q36326369-B4BDC802-11F4-4848-9F98-7A8FE7F86466Q37688589-37C351F4-595C-47F4-80B5-DC902C068CA0Q38787624-831A5C2C-B0BC-45FA-ADAC-DDF12C4C733CQ38924926-2D9C1C43-DA17-418F-9258-144A6A1A32E8Q49303366-6F47E8B5-1E0B-4B84-8B97-4192844D9E7EQ52844121-04BCC052-4769-4C34-90D1-292FFED914C8Q55017371-676A659D-493E-419F-BD15-90928C57E32D
P2860
Sodium dichloroacetate exhibits anti-leukemic activity in B-chronic lymphocytic leukemia (B-CLL) and synergizes with the p53 activator Nutlin-3.
description
2014 nî lūn-bûn
@nan
2014 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Sodium dichloroacetate exhibit ...... th the p53 activator Nutlin-3.
@ast
Sodium dichloroacetate exhibit ...... th the p53 activator Nutlin-3.
@en
Sodium dichloroacetate exhibits anti-leukemic activity in B-chronic lymphocytic leukemia
@nl
type
label
Sodium dichloroacetate exhibit ...... th the p53 activator Nutlin-3.
@ast
Sodium dichloroacetate exhibit ...... th the p53 activator Nutlin-3.
@en
Sodium dichloroacetate exhibits anti-leukemic activity in B-chronic lymphocytic leukemia
@nl
prefLabel
Sodium dichloroacetate exhibit ...... th the p53 activator Nutlin-3.
@ast
Sodium dichloroacetate exhibit ...... th the p53 activator Nutlin-3.
@en
Sodium dichloroacetate exhibits anti-leukemic activity in B-chronic lymphocytic leukemia
@nl
P2093
P2860
P921
P356
P1433
P1476
Sodium dichloroacetate exhibit ...... ith the p53 activator Nutlin-3
@en
P2093
Antonio Cuneo
Chiara Agnoletto
Claudio Celeghini
Elisabetta Melloni
Erika Rimondi
Gian Matteo Rigolin
Giorgio Zauli
Laura Brunelli
Paola Secchiero
P2860
P304
P356
10.18632/ONCOTARGET.2018
P407
P577
2014-06-01T00:00:00Z