Using the "reverse Warburg effect" to identify high-risk breast cancer patients: stromal MCT4 predicts poor clinical outcome in triple-negative breast cancers.
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pH sensing and regulation in cancerPrognostic Indications of Elevated MCT4 and CD147 across Cancer Types: A Meta-AnalysisThe fate of chemoresistance in triple negative breast cancer (TNBC)Caveolin-1, a stress-related oncotarget, in drug resistanceMolecular pathways: trafficking of metabolic resources in the tumor microenvironmentOncogenes induce the cancer-associated fibroblast phenotype: metabolic symbiosis and "fibroblast addiction" are new therapeutic targets for drug discoveryRole of oxidative stress and the microenvironment in breast cancer development and progressionA small molecule with anticancer and antimetastatic activities induces rapid mitochondrial-associated necrosis in breast cancer.On metabolic reprogramming and tumor biology: A comprehensive survey of metabolism in breast cancerHypoxia, cancer metabolism and the therapeutic benefit of targeting lactate/H(+) symportersCrucial residue involved in L-lactate recognition by human monocarboxylate transporter 4 (hMCT4)Ethanol exposure induces the cancer-associated fibroblast phenotype and lethal tumor metabolism: implications for breast cancer preventionMis-estimation and bias of hyperpolarized apparent diffusion coefficient measurements due to slice profile effects.Intratumoral lactate metabolism in Barrett's esophagus and adenocarcinoma.Fibroblast heterogeneity in the cancer wound.Expression of autophagy-related proteins according to androgen receptor and HER-2 status in estrogen receptor-negative breast cancerDeregulation of the EGFR/PI3K/PTEN/Akt/mTORC1 pathway in breast cancer: possibilities for therapeutic intervention.Ketone body utilization drives tumor growth and metastasis.Expression of reactive oxygen species-related proteins in metastatic breast cancer is dependent on the metastatic site.Identification of key binding site residues of MCT1 for AR-C155858 reveals the molecular basis of its isoform selectivity.Monocarboxylate transporter 1 inhibitors as potential anticancer agentsPrimed for cancer: Li Fraumeni Syndrome and the pre-cancerous nicheCombined Treatment of MCF-7 Cells with AICAR and Methotrexate, Arrests Cell Cycle and Reverses Warburg Metabolism through AMP-Activated Protein Kinase (AMPK) and FOXO1.Mitochondrial metabolism in cancer metastasis: visualizing tumor cell mitochondria and the "reverse Warburg effect" in positive lymph node tissue.Tumor-stroma relationships: who's the driver?Autophagy and senescence in cancer-associated fibroblasts metabolically supports tumor growth and metastasis via glycolysis and ketone productionSignificance of glycolytic metabolism-related protein expression in colorectal cancer, lymph node and hepatic metastasis.Two-compartment tumor metabolism: autophagy in the tumor microenvironment and oxidative mitochondrial metabolism (OXPHOS) in cancer cellsMetabolic reprogramming and two-compartment tumor metabolism: opposing role(s) of HIF1α and HIF2α in tumor-associated fibroblasts and human breast cancer cellsCDK inhibitors (p16/p19/p21) induce senescence and autophagy in cancer-associated fibroblasts, "fueling" tumor growth via paracrine interactions, without an increase in neo-angiogenesis.Mitochondrial fission induces glycolytic reprogramming in cancer-associated myofibroblasts, driving stromal lactate production, and early tumor growth.Ketone bodies and two-compartment tumor metabolism: stromal ketone production fuels mitochondrial biogenesis in epithelial cancer cells.Trial watch: Prognostic and predictive value of the immune infiltrate in cancerHereditary ovarian cancer and two-compartment tumor metabolism: epithelial loss of BRCA1 induces hydrogen peroxide production, driving oxidative stress and NFκB activation in the tumor stroma.Mitochondria "fuel" breast cancer metabolism: fifteen markers of mitochondrial biogenesis label epithelial cancer cells, but are excluded from adjacent stromal cellsBRCA1 mutations drive oxidative stress and glycolysis in the tumor microenvironment: implications for breast cancer prevention with antioxidant therapies.Mitochondrial dysfunction in breast cancer cells prevents tumor growth: understanding chemoprevention with metformin.Loss of p53 in stromal fibroblasts promotes epithelial cell invasion through redox-mediated ICAM1 signal.Compartment-specific activation of PPARγ governs breast cancer tumor growth, via metabolic reprogramming and symbiosis.Cancer metabolism, stemness and tumor recurrence: MCT1 and MCT4 are functional biomarkers of metabolic symbiosis in head and neck cancer.
P2860
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P2860
Using the "reverse Warburg effect" to identify high-risk breast cancer patients: stromal MCT4 predicts poor clinical outcome in triple-negative breast cancers.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Using the "reverse Warburg eff ...... riple-negative breast cancers.
@ast
Using the "reverse Warburg eff ...... riple-negative breast cancers.
@en
type
label
Using the "reverse Warburg eff ...... riple-negative breast cancers.
@ast
Using the "reverse Warburg eff ...... riple-negative breast cancers.
@en
prefLabel
Using the "reverse Warburg eff ...... riple-negative breast cancers.
@ast
Using the "reverse Warburg eff ...... riple-negative breast cancers.
@en
P2093
P2860
P50
P356
P1433
P1476
Using the "reverse Warburg eff ...... riple-negative breast cancers.
@en
P2093
Abhijit Dasgupta
Agnieszka K Witkiewicz
Nancy J Philp
Ricardo Gandara
Sharon Sneddon
Ubaldo E Martinez-Outschoorn
P2860
P304
P356
10.4161/CC.11.6.19530
P577
2012-03-15T00:00:00Z