Cutting edge: HLA-DM functions through a mechanism that does not require specific conserved hydrogen bonds in class II MHC-peptide complexes.
about
Human leukocyte Antigen-DM polymorphisms in autoimmune diseasesA step-by-step overview of the dynamic process of epitope selection by major histocompatibility complex class II for presentation to helper T cellsHLA-DO acts as a substrate mimic to inhibit HLA-DM by a competitive mechanismCrystal Structure of the HLA-DM–HLA-DR1 Complex Defines Mechanisms for Rapid Peptide SelectionConformational lability in the class II MHC 310 helix and adjacent extended strand dictate HLA-DM susceptibility and peptide exchangeDisruption of Hydrogen Bonds between Major Histocompatibility Complex Class II and the Peptide N-Terminus Is Not Sufficient to Form a Human Leukocyte Antigen-DM Receptive State of Major Histocompatibility Complex Class IISusceptibility to HLA-DM Protein Is Determined by a Dynamic Conformation of Major Histocompatibility Complex Class II Molecule Bound with PeptideComprehensive analysis of MHC class II genes in teleost fish genomes reveals dispensability of the peptide-loading DM system in a large part of vertebrates.HLA-DM captures partially empty HLA-DR molecules for catalyzed removal of peptideCharacterization of structural features controlling the receptiveness of empty class II MHC molecules.Expression of the mouse MHC class Ib H2-T11 gene product, a paralog of H2-T23 (Qa-1) with shared peptide-binding specificity.Evaluating the Role of HLA-DM in MHC Class II-Peptide Association Reactions.The Thermodynamic Mechanism of Peptide-MHC Class II Complex Formation Is a Determinant of Susceptibility to HLA-DM.HLA-DM constrains epitope selection in the human CD4 T cell response to vaccinia virus by favoring the presentation of peptides with longer HLA-DM-mediated half-livesThermodynamics of Peptide-MHC Class II Interactions: Not all Complexes are Created Equal.Mechanisms of peptide repertoire selection by HLA-DMConformational variation in structures of classical and non-classical MHCII proteins and functional implications.HLA-DM: arbiter conformationis.Structural Characteristics of HLA-DQ that May Impact DM Editing and Susceptibility to Type-1 Diabetes.HLA-DM Focuses on Conformational Flexibility Around P1 Pocket to Catalyze Peptide Exchange.Measurement of Peptide Binding to MHC Class II Molecules by Fluorescence Polarization.Structural Insights Into HLA-DM Mediated MHC II Peptide Exchange.Type 1 diabetes associated HLA-DQ2 and DQ8 molecules are relatively resistant to HLA-DM mediated release of invariant chain-derived CLIP peptidesPeptidomic analysis of type 1 diabetes associated HLA-DQ molecules and the impact of HLA-DM on peptide repertoire editing.Major Histocompatibility Complex (MHC) Class I and MHC Class II Proteins: Conformational Plasticity in Antigen Presentation.A novel method to measure HLA-DM-susceptibility of peptides bound to MHC class II molecules based on peptide binding competition assay and differential IC(50) determination.MHC class II complexes sample intermediate states along the peptide exchange pathway.
P2860
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P2860
Cutting edge: HLA-DM functions through a mechanism that does not require specific conserved hydrogen bonds in class II MHC-peptide complexes.
description
2009 nî lūn-bûn
@nan
2009 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Cutting edge: HLA-DM functions ...... lass II MHC-peptide complexes.
@ast
Cutting edge: HLA-DM functions ...... lass II MHC-peptide complexes.
@en
Cutting edge: HLA-DM functions ...... lass II MHC-peptide complexes.
@nl
type
label
Cutting edge: HLA-DM functions ...... lass II MHC-peptide complexes.
@ast
Cutting edge: HLA-DM functions ...... lass II MHC-peptide complexes.
@en
Cutting edge: HLA-DM functions ...... lass II MHC-peptide complexes.
@nl
prefLabel
Cutting edge: HLA-DM functions ...... lass II MHC-peptide complexes.
@ast
Cutting edge: HLA-DM functions ...... lass II MHC-peptide complexes.
@en
Cutting edge: HLA-DM functions ...... lass II MHC-peptide complexes.
@nl
P2093
P2860
P356
P1476
Cutting edge: HLA-DM functions ...... lass II MHC-peptide complexes.
@en
P2093
Dominique A Weber
Kari A Callaway
Peter E Jensen
Zemin Zhou
P2860
P304
P356
10.4049/JIMMUNOL.0901663
P407
P577
2009-10-01T00:00:00Z