Targeting zymogen activation to control the matriptase-prostasin proteolytic cascade. - Wikidata - wikimedia - TriplyDB

Targeting zymogen activation to control the matriptase-prostasin proteolytic cascade.

Targeting zymogen activation to control the matriptase-prostasin proteolytic cascade.

http://www.wikidata.org/entity/Q34038504

about

Human cancer cells retain modest levels of enzymatically active matriptase only in extracellular milieu following induction of zymogen activation Matriptase autoactivation is tightly regulated by the cellular chemical environments Differential subcellular localization renders HAI-2 a matriptase inhibitor in breast cancer cells but not in mammary epithelial cells N-Glycan Branching Affects the Subcellular Distribution of and Inhibition of Matriptase by HAI-2/Placental Bikunin Post-HTS case report and structural alert: Promiscuous 4-aroyl-1,5-disubstituted-3-hydroxy-2H-pyrrol-2-one actives verified by ALARM NMR.Natural Endogenous Human Matriptase and Prostasin Undergo Zymogen Activation via Independent Mechanisms in an Uncoupled Manner.

P2860

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P2860

Targeting zymogen activation to control the matriptase-prostasin proteolytic cascade.

http://www.wikidata.org/entity/Q34038504

description

2011 nî lūn-bûn

@nan

2011 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

2011年の論文

@ja

2011年論文

@yue

2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

name

Targeting zymogen activation to control the matriptase-prostasin proteolytic cascade.

@ast

Targeting zymogen activation to control the matriptase-prostasin proteolytic cascade.

@en

Targeting zymogen activation to control the matriptase-prostasin proteolytic cascade.

@nl

type

label

Targeting zymogen activation to control the matriptase-prostasin proteolytic cascade.

@ast

Targeting zymogen activation to control the matriptase-prostasin proteolytic cascade.

@en

Targeting zymogen activation to control the matriptase-prostasin proteolytic cascade.

@nl

prefLabel

Targeting zymogen activation to control the matriptase-prostasin proteolytic cascade.

@ast

Targeting zymogen activation to control the matriptase-prostasin proteolytic cascade.

@en

Targeting zymogen activation to control the matriptase-prostasin proteolytic cascade.

@nl

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Journal of Medicinal Chemistry

P1476

Targeting zymogen activation to control the matriptase-prostasin proteolytic cascade

@en

P2093

Aruna Battu

http://www.w3.org/2001/XMLSchema#string

Chen-Yong Lin

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David Weber

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Karl X Chai

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Li-Mei Chen

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Michael D Johnson

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Paul Wilder

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Ya-Wen Chen

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Zhenghong Xu

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P2860

Molecular cloning of cDNA for matriptase, a matrix-degrading serine protease with trypsin-like activity

Cellular localization of membrane-type serine protease 1 and identification of protease-activated receptor-2 and single-chain urokinase-type plasminogen activator as substrates

Ichthyosis, follicular atrophoderma, and hypotrichosis caused by mutations in ST14 is associated with impaired profilaggrin processing

Reverse biochemistry: use of macromolecular protease inhibitors to dissect complex biological processes and identify a membrane-type serine protease in epithelial cancer and normal tissue

Activation of hepatocyte growth factor and urokinase/plasminogen activator by matriptase, an epithelial membrane serine protease

A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

Tissue expression, protease specificity, and Kunitz domain functions of hepatocyte growth factor activator inhibitor-1B (HAI-1B), a new splice variant of HAI-1

The activation of matriptase requires its noncatalytic domains, serine protease domain, and its cognate inhibitor

Prometastatic effect of N-acetylglucosaminyltransferase V is due to modification and stabilization of active matriptase by adding beta 1-6 GlcNAc branching

Sphingosine 1-phosphate, present in serum-derived lipoproteins, activates matriptase

P304

7567-7578

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scholarly article

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10.1021/JM200920S

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21

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54

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2011-10-12T00:00:00Z

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51688746

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21966950

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3214968

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