A murine model of CML blast crisis induced by cooperation between BCR/ABL and NUP98/HOXA9
about
Regulation of myeloid leukaemia by the cell-fate determinant MusashiBenefits of targeting both pericytes and endothelial cells in the tumor vasculature with kinase inhibitorsAnimal models of leukemia: any closer to the real thing?The role of NUP98 gene fusions in hematologic malignancyNUP98 dysregulation in myeloid leukemogenesisATRA-induced cellular differentiation and CD38 expression inhibits acquisition of BCR-ABL mutations for CML acquired resistanceImaging hematopoietic precursor division in real time.Lis1 regulates asymmetric division in hematopoietic stem cells and in leukemiaGenetic complementation of cytokine signaling identifies central role of kinases in hematopoietic cell proliferation.JAK2 V617F in myeloid disorders: what do we know now, and where are we headed?Gene sets identified with oncogene cooperativity analysis regulate in vivo growth and survival of leukemia stem cells.Chromosome t(7;11)(p15;p15) translocation in acute myeloid leukemia coexisting with multilineage dyspoiesis and mutations in NRAS and WT1: A case report and literature reviewMouse models of myelodysplastic syndromes.NUP98-HOXD13 transgenic mice develop a highly penetrant, severe myelodysplastic syndrome that progresses to acute leukemia.Chronic myeloid leukemia: mechanisms of blastic transformationStem cells, aging, and cancer: inevitabilities and outcomes.Evidence of B cell immune responses to acute lymphoblastic leukemia in murine allogeneic hematopoietic stem cell transplantation recipients treated with donor lymphocyte infusion and/or vaccination.Cdx4 dysregulates Hox gene expression and generates acute myeloid leukemia alone and in cooperation with Meis1a in a murine model.Absence of the transcription factor CCAAT enhancer binding protein alpha results in loss of myeloid identity in bcr/abl-induced malignancy.Heterogeneous sensitivity of human acute myeloid leukemia to β-catenin down-modulation.Functionally deregulated AML1/RUNX1 cooperates with BCR-ABL to induce a blastic phase-like phenotype of chronic myelogenous leukemia in mice.The biology of chronic myelogenous leukemia:mouse models and cell adhesion.Telomerase inhibition effectively targets mouse and human AML stem cells and delays relapse following chemotherapy.p90RSK2 is essential for FLT3-ITD- but dispensable for BCR-ABL-induced myeloid leukemia.Right on target: eradicating leukemic stem cells.Cooperation of cytokine signaling with chimeric transcription factors in leukemogenesis: PML-retinoic acid receptor alpha blocks growth factor-mediated differentiation.Memory T cells from minor histocompatibility antigen-vaccinated and virus-immune donors improve GVL and immune reconstitution.NUP98 gene fusions and hematopoietic malignancies: common themes and new biologic insightsLeukemia stem cells: the root of chronic myeloid leukemiaMechanisms controlling pathogenesis and survival of leukemic stem cells.Leukemia stem cells in a genetically defined murine model of blast-crisis CML.Functional inhibition of osteoblastic cells in an in vivo mouse model of myeloid leukemiaAnimal models of acute myelogenous leukaemia - development, application and future perspectives.A novel mouse model identifies cooperating mutations and therapeutic targets critical for chronic myeloid leukemia progression.Mouse embryonic stem cells that express a NUP98-HOXD13 fusion protein are impaired in their ability to differentiate and can be complemented by BCR-ABL.β-Arrestin2 mediates the initiation and progression of myeloid leukemia.Effector memory CD4+ T cells mediate graft-versus-leukemia without inducing graft-versus-host disease.CD150(-) Side Population Defines Leukemia Stem Cells in a BALB/c Mouse Model of CML and Is Depleted by Genetic Loss of SIRT1Chromatin-prebound Crm1 recruits Nup98-HoxA9 fusion to induce aberrant expression of Hox cluster genes.Somatic mutations and germline sequence variants in the expressed tyrosine kinase genes of patients with de novo acute myeloid leukemia.
P2860
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P2860
A murine model of CML blast crisis induced by cooperation between BCR/ABL and NUP98/HOXA9
description
2002 nî lūn-bûn
@nan
2002 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
A murine model of CML blast crisis induced by cooperation between BCR/ABL and NUP98/HOXA9
@ast
A murine model of CML blast crisis induced by cooperation between BCR/ABL and NUP98/HOXA9
@en
A murine model of CML blast crisis induced by cooperation between BCR/ABL and NUP98/HOXA9
@nl
type
label
A murine model of CML blast crisis induced by cooperation between BCR/ABL and NUP98/HOXA9
@ast
A murine model of CML blast crisis induced by cooperation between BCR/ABL and NUP98/HOXA9
@en
A murine model of CML blast crisis induced by cooperation between BCR/ABL and NUP98/HOXA9
@nl
prefLabel
A murine model of CML blast crisis induced by cooperation between BCR/ABL and NUP98/HOXA9
@ast
A murine model of CML blast crisis induced by cooperation between BCR/ABL and NUP98/HOXA9
@en
A murine model of CML blast crisis induced by cooperation between BCR/ABL and NUP98/HOXA9
@nl
P2093
P2860
P356
P1476
A murine model of CML blast crisis induced by cooperation between BCR/ABL and NUP98/HOXA9
@en
P2093
Ajeeta B Dash
D Gary Gilliland
David Housman
Ema Anastasiadou
Jeffery L Kutok
Julian Borrow
Kathleen Lindahl
Michael H Tomasson
Richard A Van Etten
Shaoguang Li
P2860
P304
P356
10.1073/PNAS.102583199
P407
P577
2002-05-01T00:00:00Z