Leaky termination at premature stop codons antagonizes nonsense-mediated mRNA decay in S. cerevisiae
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Interactions between UPF1, eRFs, PABP and the exon junction complex suggest an integrated model for mammalian NMD pathwaysRPS25 is essential for translation initiation by the Dicistroviridae and hepatitis C viral IRESsElongation factor eEF1B modulates functions of the release factors eRF1 and eRF3 and the efficiency of translation termination in yeastTpa1p is part of an mRNP complex that influences translation termination, mRNA deadenylation, and mRNA turnover in Saccharomyces cerevisiae.The Sua5 protein is essential for normal translational regulation in yeast.The shuttling protein Npl3 promotes translation termination accuracy in Saccharomyces cerevisiae.Translation initiation factor eIF3 promotes programmed stop codon readthrough.Ebs1p, a negative regulator of gene expression controlled by the Upf proteins in the yeast Saccharomyces cerevisiae.Evidence against a direct role for the Upf proteins in frameshifting or nonsense codon readthrough.Systematic identification and functional screens of uncharacterized proteins associated with eukaryotic ribosomal complexes.Transcript selection and the recruitment of mRNA decay factors for NMD in Saccharomyces cerevisiaeFunctions of the nonsense-mediated mRNA decay pathway in Drosophila developmentTranslation initiation factors eIF3 and HCR1 control translation termination and stop codon read-through in yeast cellsChemical-Induced Read-Through at Premature Termination Codons Determined by a Rapid Dual-Fluorescence System Based on S. cerevisiaeRibosome profiling reveals pervasive and regulated stop codon readthrough in Drosophila melanogasterMethylation of yeast ribosomal protein Rpl3 promotes translational elongation fidelityHistidine methylation of yeast ribosomal protein Rpl3p is required for proper 60S subunit assembly.Systematic analysis of bicistronic reporter assay dataInactivation of NMD increases viability of sup45 nonsense mutants in Saccharomyces cerevisiae.Expression of the eRF1 translation termination factor is controlled by an autoregulatory circuit involving readthrough and nonsense-mediated decay in plants.Transcripts expressed using a bicistronic vector pIREShyg2 are sensitized to nonsense-mediated mRNA decay.Genetic interactions between [PSI+] and nonstop mRNA decay affect phenotypic variationVariants in SUP45 and TRM10 underlie natural variation in translation termination efficiency in Saccharomyces cerevisiaeNonsense-mediated mRNA decay maintains translational fidelity by limiting magnesium uptakeElongator complex influences telomeric gene silencing and DNA damage response by its role in wobble uridine tRNA modification.Targets for cystic fibrosis therapy: proteomic analysis and correction of mutant cystic fibrosis transmembrane conductance regulatorGenetic basis of hidden phenotypic variation revealed by increased translational readthrough in yeast.Loss of nonsense mediated decay suppresses mutations in Saccharomyces cerevisiae TRA1Protein multifunctionality: principles and mechanisms.Distinct paths to stop codon reassignment by the variant-code organisms Tetrahymena and Euplotes.Site-specific release of nascent chains from ribosomes at a sense codon.Drosophila Upf1 and Upf2 loss of function inhibits cell growth and causes animal death in a Upf3-independent mannerInteraction between the poly(A)-binding protein Pab1 and the eukaryotic release factor eRF3 regulates translation termination but not mRNA decay in Saccharomyces cerevisiaeMultiple transcripts from a 3'-UTR reporter vary in sensitivity to nonsense-mediated mRNA decay in Saccharomyces cerevisiaeBoth the autophagy and proteasomal pathways facilitate the Ubp3p-dependent depletion of a subset of translation and RNA turnover factors during nitrogen starvation in Saccharomyces cerevisiae.New genetic regulators question relevance of abundant yolk protein production in C. elegans.A system for coordinated analysis of translational readthrough and nonsense-mediated mRNA decay.Messenger RNA regulation: to translate or to degrade.Rules of UGA-N decoding by near-cognate tRNAs and analysis of readthrough on short uORFs in yeastViral Evasion and Manipulation of Host RNA Quality Control Pathways.
P2860
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P2860
Leaky termination at premature stop codons antagonizes nonsense-mediated mRNA decay in S. cerevisiae
description
2004 nî lūn-bûn
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2004 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Leaky termination at premature ...... ed mRNA decay in S. cerevisiae
@ast
Leaky termination at premature ...... ed mRNA decay in S. cerevisiae
@en
Leaky termination at premature ...... ed mRNA decay in S. cerevisiae
@nl
type
label
Leaky termination at premature ...... ed mRNA decay in S. cerevisiae
@ast
Leaky termination at premature ...... ed mRNA decay in S. cerevisiae
@en
Leaky termination at premature ...... ed mRNA decay in S. cerevisiae
@nl
prefLabel
Leaky termination at premature ...... ed mRNA decay in S. cerevisiae
@ast
Leaky termination at premature ...... ed mRNA decay in S. cerevisiae
@en
Leaky termination at premature ...... ed mRNA decay in S. cerevisiae
@nl
P2093
P2860
P356
P1433
P1476
Leaky termination at premature ...... ed mRNA decay in S. cerevisiae
@en
P2093
Anisa Kaenjak-Angeletti
David M Bedwell
Jessica Lanier
Joe Salas-Marco
Kim M Keeling
P2860
P304
P356
10.1261/RNA.5147804
P407
P577
2004-04-01T00:00:00Z