The major murine systemic lupus erythematosus susceptibility locus, Sle1, is a cluster of functionally related genes. - Wikidata - wikimedia - TriplyDB

The major murine systemic lupus erythematosus susceptibility locus, Sle1, is a cluster of functionally related genes.

The major murine systemic lupus erythematosus susceptibility locus, Sle1, is a cluster of functionally related genes.

http://www.wikidata.org/entity/Q34104677

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Increased expression of SLAM receptors SLAMF3 and SLAMF6 in systemic lupus erythematosus T lymphocytes promotes Th17 differentiation Spontaneous autoimmunity in 129 and C57BL/6 mice-implications for autoimmunity described in gene-targeted mice Genetic epidemiology: systemic lupus erythematosus Disturbed T Cell Signaling and Altered Th17 and Regulatory T Cell Subsets in the Pathogenesis of Systemic Lupus Erythematosus Epistasis and immunity: the role of genetic interactions in autoimmune diseases Leukocyte Beta-Catenin Expression Is Disturbed in Systemic Lupus Erythematosus B cell receptor editing in tolerance and autoimmunity Genetic modifiers of systemic lupus erythematosus in FcgammaRIIB(-/-) mice Pathogenesis of proliferative lupus nephritis from a historical and personal perspective.Breaking tolerance to double stranded DNA, nucleosome, and other nuclear antigens is not required for the pathogenesis of lupus glomerulonephritis.From QTL to candidate gene: a genetic approach to alcoholism research Cgnz1 allele confers kidney resistance to damage preventing progression of immune complex-mediated acute lupus glomerulonephritis.Pathogenesis of systemic lupus erythematosus revisited 2011: end organ resistance to damage, autoantibody initiation and diversification, and HLA-DR.Genetic approach to study lupus glomerulonephritis.Auto-antibody production and glomerulonephritis in congenic Slamf1-/- and Slamf2-/- [B6.129] but not in Slamf1-/- and Slamf2-/- [BALB/c.129] mice.The lupus-prone NZM2410/NZW strain-derived Sle1b sublocus alters the germinal center checkpoint in female mice in a B cell-intrinsic manner.Positional cloning of Ncf1--a piece in the puzzle of arthritis genetics.Dissection of a locus on mouse chromosome 5 reveals arthritis promoting and inhibitory genes Defective B-cell response to T-dependent immunization in lupus-prone mice Genetic variants of Adam17 differentially regulate TGFβ signaling to modify vascular pathology in mice and humans.Multiple tolerance defects contribute to the breach of B cell tolerance in New Zealand Black chromosome 1 congenic mice Antigen-specific responses and ANA production in B6.Sle1b mice: a role for SAP The lupus susceptibility locus Sle1 breaches peripheral B cell tolerance at the antibody-forming cell and germinal center checkpoints A stop codon polymorphism of Toll-like receptor 5 is associated with resistance to systemic lupus erythematosus.Polymorphism at the C-reactive protein locus influences gene expression and predisposes to systemic lupus erythematosus.Macrophages and immunologic inflammation of the kidney.Murine lupus susceptibility locus Sle1a requires the expression of two sub-loci to induce inflammatory T cells Early, transient depletion of plasmacytoid dendritic cells ameliorates autoimmunity in a lupus model.The rat Toxo1 locus directs toxoplasmosis outcome and controls parasite proliferation and spreading by macrophage-dependent mechanisms.Yaa autoimmune phenotypes are conferred by overexpression of TLR7.B cell-intrinsic TLR7 signaling is essential for the development of spontaneous germinal centers.Eae19, a new locus on rat chromosome 15 regulating experimental autoimmune encephalomyelitis.Susceptibility genes in the pathogenesis of murine lupus.A Tlr7 translocation accelerates systemic autoimmunity in murine lupus.An allelic variant of Crry in the murine Sle1c lupus susceptibility interval is not impaired in its ability to regulate complement activation.Murine lupus susceptibility locus Sle2 activates DNA-reactive B cells through two sub-loci with distinct phenotypes Three checkpoints in lupus development: central tolerance in adaptive immunity, peripheral amplification by innate immunity and end-organ inflammation.The SLAM family member CD48 (Slamf2) protects lupus-prone mice from autoimmune nephritis Cutting edge: an NK cell-independent role for Slamf4 in controlling humoral autoimmunity.B cell inhibitory receptors and autoimmunity.

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The major murine systemic lupus erythematosus susceptibility locus, Sle1, is a cluster of functionally related genes.

http://www.wikidata.org/entity/Q34104677

description

2001 nî lūn-bûn

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2001 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2001 թվականի հունվարին հրատարակված գիտական հոդված

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2001年の論文

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2001年学术文章

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2001年学术文章

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2001年学术文章

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2001年学术文章

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2001年学术文章

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2001年學術文章

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name

The major murine systemic lupu ...... of functionally related genes.

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The major murine systemic lupu ...... of functionally related genes.

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The major murine systemic lupu ...... of functionally related genes.

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type

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The major murine systemic lupu ...... of functionally related genes.

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The major murine systemic lupu ...... of functionally related genes.

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The major murine systemic lupu ...... of functionally related genes.

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The major murine systemic lupu ...... of functionally related genes.

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The major murine systemic lupu ...... of functionally related genes.

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The major murine systemic lupu ...... of functionally related genes.

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Proceedings of the National Academy of Sciences of the United States of America

P1476

The major murine systemic lupu ...... of functionally related genes.

@en

P2093

B P Croker

http://www.w3.org/2001/XMLSchema#string

E K Wakeland

http://www.w3.org/2001/XMLSchema#string

K R Blenman

http://www.w3.org/2001/XMLSchema#string

L Morel

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P2860

Fc gamma RIIA alleles are heritable risk factors for lupus nephritis in African Americans

Autoantibodies associated with lupus induced by diverse drugs target a similar epitope in the (H2A-H2B)-DNA complex

Genetic dissection of systemic lupus erythematosus.

PARP alleles within the linked chromosomal region are associated with systemic lupus erythematosus

Genetic dissection of lupus pathogenesis: a recipe for nephrophilic autoantibodies.

Genetic reconstitution of systemic lupus erythematosus immunopathology with polycongenic murine strains.

Lupus susceptibility loci in New Zealand mice.

A novel polymorphism of FcgammaRIIIa (CD16) alters receptor function and predisposes to autoimmune disease.

Genetic dissection of SLE pathogenesis. Sle1 on murine chromosome 1 leads to a selective loss of tolerance to H2A/H2B/DNA subnucleosomes.

Production of congenic mouse strains carrying genomic intervals containing SLE-susceptibility genes derived from the SLE-prone NZM2410 strain.

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1787-1792

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10.1073/PNAS.031336098

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4

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98

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12158401

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11172029

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susceptibility locus

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29335

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