A thrombin receptor function for platelet glycoprotein Ib-IX unmasked by cleavage of glycoprotein V.
about
Evidence for a role of ADAM17 (TACE) in the regulation of platelet glycoprotein VPlatelets and platelet adhesion molecules: novel mechanisms of thrombosis and anti-thrombotic therapiesPlatelets and coagulation in infectionSequential activation of p38 and ERK pathways by cGMP-dependent protein kinase leading to activation of the platelet integrin alphaIIb beta3In vivo relevance for platelet glycoprotein Ibalpha residue Tyr276 in thrombus formation.Understanding the therapeutic action of recombinant factor VIIa in platelet disorders.Platelets are versatile cells: New discoveries in hemostasis, thrombosis, immune responses, tumor metastasis and beyond.Role of thrombin signalling in platelets in haemostasis and thrombosis.Contribution of protease-activated receptors 1 and 4 and glycoprotein Ib-IX-V in the G(i)-independent activation of platelet Rap1B by thrombin.Signaling events underlying thrombus formation.A new "kid" on the platelet thrombin receptor "block": glycoprotein Ib-IX-VReceptors, rafts, and microvesicles in thrombosis and inflammation.The interaction of thrombin with blood platelets.Recombinant activated factor VII and the anaesthetist.Signaling-mediated cooperativity between glycoprotein Ib-IX and protease-activated receptors in thrombin-induced platelet activationAllosterism-based simultaneous, dual anticoagulant and antiplatelet action: allosteric inhibitor targeting the glycoprotein Ibα-binding and heparin-binding site of thrombin.Thrombin.Platelet receptors and signaling in the dynamics of thrombus formation.Platelet receptor signaling in thrombus formation.Platelet signaling-a primer.Regulation of platelet membrane protein shedding in health and disease.Basic mechanisms of platelet receptor shedding.New Concepts and Mechanisms of Platelet Activation Signaling.Controlled shedding of platelet glycoprotein (GP)VI and GPIb-IX-V by ADAM family metalloproteinases.TRAP induces more intense tyrosine phosphorylation than thrombin with differential ultrastructural features.A mitogen-activated protein kinase-dependent signaling pathway in the activation of platelet integrin alpha IIbbeta3.Glycoprotein Ib-mediated platelet activation. A signalling pathway triggered by thrombin.A peptide isolated from alpha B-crystallin is a novel and potent inhibitor of platelet aggregation via dual prevention of PAR-1 and GPIb/V/IX.The GPIb-thrombin pathway: evidence for a novel role of fibrin in platelet aggregation.A platelet secretion pathway mediated by cGMP-dependent protein kinase.Thrombin activation of factor XI on activated platelets requires the interaction of factor XI and platelet glycoprotein Ib alpha with thrombin anion-binding exosites I and II, respectively.Platelet binding and activity of a factor VIIa variant with enhanced tissue factor independent activity.Inhibition of gamma-thrombin-induced human platelet aggregation by histone H1subtypes and H1.3 fragments.Increased soluble glycoprotein V concentration during the acute onset of unstable angina pectoris in association with chronic cigarette smoking.Thrombin induces GPIb-IX-mediated fibrin binding to alphaIIbbeta3 in a reconstituted Chinese hamster ovary cell model.14-3-3 proteins in platelet biology and glycoprotein Ib-IX signaling.
P2860
Q24293698-24522AC9-04C4-4AF0-9683-1E91B9BF24CCQ28068448-F2F857ED-1AFA-4B52-86BF-91A9D32966ECQ28079908-1C46B9DB-9A41-4811-B10D-5E8AAC361FDCQ28192455-8D9C9B11-21E6-433B-BF39-18E1C6A456C5Q33323650-17162C11-DC81-4689-8C24-18A504A158FBQ33382014-5F5C8AEF-7393-4B27-9C10-490F290C4B83Q33432917-7B60DD3A-4550-4D47-9EB0-74B263574E2BQ34090283-41DDDB17-967B-4BC1-BE36-99A2230E4DB6Q34312730-4DD2A1D0-4981-41A2-9850-BF5C9B024970Q35181664-88913C4F-4864-4450-A441-F690A9D2EABEQ35915668-DAAFB0EA-3568-4724-A08F-A5CF059B9862Q36230863-CF0F0E7B-AFE6-4017-9A82-7AC52003893DQ36291249-8FDE032A-A0F4-44E2-A156-EF14D60EA51BQ36313315-40E5F019-AE86-4DE2-AD02-1971A96D6D66Q36547814-E56CF91F-F756-4AC6-A572-57BB841E7DCFQ36788507-D720E796-0F52-4A0A-BE77-53F25AC0DB3AQ36800534-FA0EE9DB-198C-4B4E-869C-8E22EEBA7BBEQ37175605-03E592AA-B0C2-41DA-BEEA-A621E36501A0Q37807924-74CE1764-73DB-4D34-A0E4-2F1899121766Q37982455-B05DA43F-E996-4DDB-B938-43742A312657Q38919547-EEA94DFA-09EA-4C6E-A2D8-17F4DC081140Q38990156-BAD9A67C-0110-4C34-8CD6-E841B28831EAQ39147112-ED6EDF90-3713-4E65-B4AF-B6ADE1F9F55FQ40143775-D9FF3918-05D9-4F48-934E-7C27A68BA2B0Q42855555-099AEAE2-72FA-47B3-9CD4-D33C6219910EQ43720106-D5178028-2041-49F4-96B3-789248EC3DACQ44503897-1E5FA00F-768B-4B58-9FDE-1F14A8D27439Q44747325-E893A24C-6B6A-4569-94DB-AEE693207F0DQ44792157-9AF36118-46C5-4FBD-9300-6E9204E5D1E4Q44997709-F3C2A654-DC33-4F3A-8F1F-3F00497C3414Q45063820-3B48E543-6A49-43C9-B13D-BC9A251CF54AQ45866827-5635CA7D-7C5E-4C69-938F-D2B5ABB5F40BQ45918028-D22E6A38-F10E-40D4-8614-FF4FB177A3EBQ46728497-5BD3D259-3F15-4029-9C8B-4DF9570BE929Q51803698-168D00E7-9072-45A1-A29B-4486CB364B4CQ52330622-306A6E18-D8EC-4149-880C-3BF5A45AF157
P2860
A thrombin receptor function for platelet glycoprotein Ib-IX unmasked by cleavage of glycoprotein V.
description
2001 nî lūn-bûn
@nan
2001 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
A thrombin receptor function f ...... by cleavage of glycoprotein V.
@en
A thrombin receptor function f ...... by cleavage of glycoprotein V.
@nl
type
label
A thrombin receptor function f ...... by cleavage of glycoprotein V.
@en
A thrombin receptor function f ...... by cleavage of glycoprotein V.
@nl
prefLabel
A thrombin receptor function f ...... by cleavage of glycoprotein V.
@en
A thrombin receptor function f ...... by cleavage of glycoprotein V.
@nl
P2093
P2860
P356
P1476
A thrombin receptor function f ...... by cleavage of glycoprotein V.
@en
P2093
P2860
P304
P356
10.1073/PNAS.98.4.1823
P407
P577
2001-02-01T00:00:00Z