Polycystin-1 activation of c-Jun N-terminal kinase and AP-1 is mediated by heterotrimeric G proteins. - Wikidata - wikimedia - TriplyDB

Polycystin-1 activation of c-Jun N-terminal kinase and AP-1 is mediated by heterotrimeric G proteins.

Polycystin-1 activation of c-Jun N-terminal kinase and AP-1 is mediated by heterotrimeric G proteins.

http://www.wikidata.org/entity/Q34120390

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Polycystin-1 and polycystin-2 regulate the cell cycle through the helix-loop-helix inhibitor Id2 A polycystin-2 (TRPP2) dimerization domain essential for the function of heteromeric polycystin complexes Carboxy terminal tail of polycystin-1 regulates localization of TSC2 to repress mTOR The Role of G-Protein-Coupled Receptor Proteolysis Site Cleavage of Polycystin-1 in Renal Physiology and Polycystic Kidney Disease Role of the Polycystins in Cell Migration, Polarity, and Tissue Morphogenesis Accessory proteins for heterotrimeric G-proteins in the kidney Polycystin-1 cleavage and the regulation of transcriptional pathways Mechanical stimuli induce cleavage and nuclear translocation of the polycystin-1 C terminus Systems biology approach to identify transcriptome reprogramming and candidate microRNA targets during the progression of polycystic kidney disease TAZ promotes PC2 degradation through a SCFbeta-Trcp E3 ligase complex Native polycystin 2 functions as a plasma membrane Ca2+-permeable cation channel in renal epithelia Polycystin-1 induces cell migration by regulating phosphatidylinositol 3-kinase-dependent cytoskeletal rearrangements and GSK3beta-dependent cell cell mechanical adhesion.Mutant polycystin-2 induces proliferation in primary rat tubular epithelial cells in a STAT-1/p21-independent fashion accompanied instead by alterations in expression of p57KIP2 and Cdk2.A novel mouse model reveals that polycystin-1 deficiency in ependyma and choroid plexus results in dysfunctional cilia and hydrocephalus.Receptor protein tyrosine phosphatases are novel components of a polycystin complex Polycystin-1 protein level determines activity of the Galpha12/JNK apoptosis pathway.Mechanisms of p53-mediated repression of the human polycystic kidney disease-1 promoter Implications of non-canonical G-protein signaling for the immune system Activator of G protein signaling 3 promotes epithelial cell proliferation in PKD.The cell biology of polycystic kidney disease Protein phosphatase-1α interacts with and dephosphorylates polycystin-1 MAP/ERK kinase kinase 1 (MEKK1) mediates transcriptional repression by interacting with polycystic kidney disease-1 (PKD1) promoter-bound p53 tumor suppressor protein Kidney: polycystic kidney disease.Polycystin-1 induces resistance to apoptosis through the phosphatidylinositol 3-kinase/Akt signaling pathway.Effect of PKD1 gene missense mutations on polycystin-1 membrane topogenesis.New insights into ciliary function: kidney cysts and photoreceptors.Structural model of the TRPP2/PKD1 C-terminal coiled-coil complex produced by a combined computational and experimental approach.Cilium, centrosome and cell cycle regulation in polycystic kidney disease.Inactivation of integrin-β1 prevents the development of polycystic kidney disease after the loss of polycystin-1.Conditional deletion of Pkd1 in osteocytes disrupts skeletal mechanosensing in mice.Autosomal dominant polycystic kidney disease (ADPKD, MIM 173900, PKD1 and PKD2 genes, protein products known as polycystin-1 and polycystin-2).Regulation of Polycystin-1 Function by Calmodulin Binding.G-protein signaling modulator 1 deficiency accelerates cystic disease in an orthologous mouse model of autosomal dominant polycystic kidney disease.Diagnosis, pathogenesis, and treatment prospects in cystic kidney disease.Polycystin-1 regulates skeletogenesis through stimulation of the osteoblast-specific transcription factor RUNX2-II.Infused Fc-tagged beta-glucuronidase crosses the placenta and produces clearance of storage in utero in mucopolysaccharidosis VII mice.Hyperproliferation of PKD1 cystic cells is induced by insulin-like growth factor-1 activation of the Ras/Raf signalling system.Polycystic kidney disease and renal injury repair: common pathways, fluid flow, and the function of polycystin-1.Growth of cranial synchondroses and sutures requires polycystin-1.Characterization of PKD protein-positive exosome-like vesicles.

P2860

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P2860

Polycystin-1 activation of c-Jun N-terminal kinase and AP-1 is mediated by heterotrimeric G proteins.

http://www.wikidata.org/entity/Q34120390

description

2002 nî lūn-bûn

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2002 թուականի Մարտին հրատարակուած գիտական յօդուած

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2002 թվականի մարտին հրատարակված գիտական հոդված

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2002年の論文

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2002年論文

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2002年論文

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2002年論文

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2002年論文

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2002年論文

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2002年论文

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name

Polycystin-1 activation of c-J ...... by heterotrimeric G proteins.

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Polycystin-1 activation of c-J ...... by heterotrimeric G proteins.

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Polycystin-1 activation of c-J ...... by heterotrimeric G proteins.

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type

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Polycystin-1 activation of c-J ...... by heterotrimeric G proteins.

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Polycystin-1 activation of c-J ...... by heterotrimeric G proteins.

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Polycystin-1 activation of c-J ...... by heterotrimeric G proteins.

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Polycystin-1 activation of c-J ...... by heterotrimeric G proteins.

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Polycystin-1 activation of c-J ...... by heterotrimeric G proteins.

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Polycystin-1 activation of c-J ...... by heterotrimeric G proteins.

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Journal of Biological Chemistry

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Polycystin-1 activation of c-J ...... by heterotrimeric G proteins.

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P2093

Anna-Maria Frischauf

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Brenda S Magenheimer

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Christopher A Zien

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James P Calvet

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Robin L Maser

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Stephen C Parnell

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19566-19572

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scholarly article

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10.1074/JBC.M201875200

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22

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277

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2002-03-23T00:00:00Z

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11912216

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