An unequal cross-over event within the CYP2D gene cluster generates a chimeric CYP2D7/CYP2D6 gene which is associated with the poor metabolizer phenotype

An unequal cross-over event within the CYP2D gene cluster generates a chimeric CYP2D7/CYP2D6 gene which is associated with the poor metabolizer phenotype

Item
http://www.wikidata.org/entity/Q34347560
Genetic polymorphisms of human N-acetyltransferase, cytochrome P450, glutathione-S-transferase, and epoxide hydrolase enzymes: relevance to xenobiotic metabolism and toxicity.CYP2D6: novel genomic structures and alleles.Cytochrome P450 2D6 variants in a Caucasian population: allele frequencies and phenotypic consequences.Molecular evolution of the CYP2D subfamily in primates: purifying selection on substrate recognition sites without the frequent or long-tract gene conversionPolymorphism of human cytochrome P450 2D6 and its clinical significance: Part I.Complexities of CYP2D6 gene analysis and interpretation.Identification of Novel CYP2D7-2D6 Hybrids: Non-Functional and Functional Variants.Development of a tetraplex PCR assay for CYP2D6 genotyping in degraded DNA samples.CYP2D7-2D6 hybrid tandems: identification of novel CYP2D6 duplication arrangements and implications for phenotype prediction.The CYP2D6 gene locus in South African Coloureds: unique allele distributions, novel alleles and gene arrangements.Cytochrome P4502D6 (CYP2D6) gene locus heterogeneity: characterization of gene duplication events.
P2860

An unequal cross-over event within the CYP2D gene cluster generates a chimeric CYP2D7/CYP2D6 gene which is associated with the poor metabolizer phenotype

Item
http://www.wikidata.org/entity/Q34347560
description
1995 nî lūn-bûn
@nan
1995 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
An unequal cross-over event wi ...... the poor metabolizer phenotype
@ast
An unequal cross-over event wi ...... the poor metabolizer phenotype
@en
An unequal cross-over event wi ...... the poor metabolizer phenotype
@nl
type
label
An unequal cross-over event wi ...... the poor metabolizer phenotype
@ast
An unequal cross-over event wi ...... the poor metabolizer phenotype
@en
An unequal cross-over event wi ...... the poor metabolizer phenotype
@nl
prefLabel
An unequal cross-over event wi ...... the poor metabolizer phenotype
@ast
An unequal cross-over event wi ...... the poor metabolizer phenotype
@en
An unequal cross-over event wi ...... the poor metabolizer phenotype
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P932
P356
P1433
P1476
An unequal cross-over event wi ...... the poor metabolizer phenotype
@en
P2093
P2860
P304
P31
P356
10.1111/J.1365-2125.1995.TB04558.X
P407
P433
P478
P577
P5875
P698
P932