Cytochrome P4502D6 (CYP2D6) gene locus heterogeneity: characterization of gene duplication events.
about
A novel simple method for determining CYP2D6 gene copy number and identifying allele(s) with duplication/multiplicationLong-Read Single Molecule Real-Time Full Gene Sequencing of Cytochrome P450-2D6.Drug-metabolizing enzyme genotypes and aggressive behavior treatment response in hospitalized pediatric psychiatric patients.CYP2D6: novel genomic structures and alleles.Genetic polymorphisms and drug interactions modulating CYP2D6 and CYP3A activities have a major effect on oxycodone analgesic efficacy and safetySerotonin pathway polymorphisms and the treatment of major depressive disorder and anxiety disorders.Introduction of the AmpliChip CYP450 Test to a South African cohort: a platform comparative prospective cohort studyPredictors of risperidone and 9-hydroxyrisperidone serum concentration in children and adolescentsSNP genotyping using TaqMan technology: the CYP2D6*17 assay conundrum.Current State and Future Prospects of Direct-to-Consumer PharmacogeneticsCYP2D6 Haplotype Determination Using Long Range Allele-Specific Amplification: Resolution of a Complex Genotype and a Discordant Genotype Involving the CYP2D6*59 Allele.Characterization of 137 Genomic DNA Reference Materials for 28 Pharmacogenetic Genes: A GeT-RM Collaborative ProjectCYP2D7 Sequence Variation Interferes with TaqMan CYP2D6 (*) 15 and (*) 35 Genotyping.Risperidone-associated adverse drug reactions and CYP2D6 polymorphisms in a South African cohort.Evaluation of a [13C]-dextromethorphan breath test to assess CYP2D6 phenotype.Single dose, CYP2D6 genotype-stratified pharmacokinetic study of atomoxetine in children with ADHDCYP2D6 polymorphism: implications for antipsychotic drug response, schizophrenia and personality traits.Characterization of Atomoxetine Biotransformation and Implications for Development of PBPK Models for Dose Individualization in Children.Cytochrome P450 2D6 polymorphisms and predicted opioid metabolism in African American children with sickle cell disease.PhRMA white paper on ADME pharmacogenomics.Common CYP2D6 polymorphisms affecting alternative splicing and transcription: long-range haplotypes with two regulatory variants modulate CYP2D6 activity.Implementation of CYP2D6 genotyping in psychiatry.Pharmacogenetic considerations in the treatment of psychiatric disorders.Pharmacogenetics of antidepressant drugs: current clinical practice and future directions.Pharmacogenomics of opioids and perioperative pain management.Complexities of CYP2D6 gene analysis and interpretation.Pediatric perspective on pharmacogenomics.Interethnic variability of CYP2D6 alleles and of predicted and measured metabolic phenotypes across world populations.Impact of physiological, pathological and environmental factors on the expression and activity of human cytochrome P450 2D6 and implications in precision medicine.Association between CYP2D6 Genotypes and the Risk of Antidepressant Discontinuation, Dosage Modification and the Occurrence of Maternal Depression during Pregnancy.Flexible and Scalable Full-Length CYP2D6 Long Amplicon PacBio Sequencing.Identification of Novel CYP2D7-2D6 Hybrids: Non-Functional and Functional Variants.Polymorphisms in CYP2D6 may predict methamphetamine related heart failure.CYP2D6, SULT1A1 and UGT2B17 copy number variation: quantitative detection by multiplex PCR.CYP2D6 and pharmacogenomics: where does future research need to focus? Part 1: technical aspects.CYP2D6 genotyping for psychiatric patients treated with risperidone: considerations for cost-effectiveness studies.Characterization of the CYP2D6 gene locus and metabolic activity in Indo- and Afro-Trinidadians: discovery of novel allelic variants.CYP2D7-2D6 hybrid tandems: identification of novel CYP2D6 duplication arrangements and implications for phenotype prediction.Constellation: a tool for rapid, automated phenotype assignment of a highly polymorphic pharmacogene, CYP2D6, from whole-genome sequences.Use of RNA-seq to determine variation in canine cytochrome P450 mRNA expression between blood, liver, lung, kidney and duodenum in healthy beagles.
P2860
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P2860
Cytochrome P4502D6 (CYP2D6) gene locus heterogeneity: characterization of gene duplication events.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh-hant
name
Cytochrome P4502D6 (CYP2D6) ge ...... on of gene duplication events.
@en
Cytochrome P4502D6
@nl
type
label
Cytochrome P4502D6 (CYP2D6) ge ...... on of gene duplication events.
@en
Cytochrome P4502D6
@nl
prefLabel
Cytochrome P4502D6 (CYP2D6) ge ...... on of gene duplication events.
@en
Cytochrome P4502D6
@nl
P2093
P356
P1476
Cytochrome P4502D6 (CYP2D6) ge ...... ion of gene duplication events
@en
P2093
Alander SW
Brousseau DC
Dianne Bradford L
Divakaran K
Johnson JA
McCarver DG
Ndjountché L
Steven Leeder J
Wayne Riggs K
P304
P356
10.1038/SJ.CLPT.6100033
P407
P577
2007-02-01T00:00:00Z