DJ-1 acts in parallel to the PINK1/parkin pathway to control mitochondrial function and autophagy. - Wikidata - wikimedia - TriplyDB

DJ-1 acts in parallel to the PINK1/parkin pathway to control mitochondrial function and autophagy.

DJ-1 acts in parallel to the PINK1/parkin pathway to control mitochondrial function and autophagy.

http://www.wikidata.org/entity/Q34399382

about

Genetic perspective on the role of the autophagy-lysosome pathway in Parkinson disease The mitochondrial intramembrane protease PARL cleaves human Pink1 to regulate Pink1 trafficking DJ-1 interacts with RACK1 and protects neurons from oxidative-stress-induced apoptosis The role of oxidative stress in Parkinson's disease Inactivation of Pink1 gene in vivo sensitizes dopamine-producing neurons to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and can be rescued by autosomal recessive Parkinson disease genes, Parkin or DJ-1 Human DJ-1 and its homologs are novel glyoxalases Structure and Function of Parkin, PINK1, and DJ-1, the Three Musketeers of Neuroprotection Autophagy, mitochondria and oxidative stress: cross-talk and redox signalling Mutant LRRK2 elicits calcium imbalance and depletion of dendritic mitochondria in neurons Mitochondrial dysfunction in ataxia-telangiectasia Mitochondrial dysfunction in Parkinson's disease Activation Mechanism of LRRK2 and Its Cellular Functions in Parkinson's Disease Parkinson's disease proteins: Novel mitochondrial targets for cardioprotection Mitochondria: A Therapeutic Target for Parkinson's Disease?Deconvoluting the complexity of autophagy and Parkinson's disease for potential therapeutic purpose Electron Transport Disturbances and Neurodegeneration: From Albert Szent-Györgyi's Concept (Szeged) till Novel Approaches to Boost Mitochondrial Bioenergetics Cellular models to investigate biochemical pathways in Parkinson's disease Mitochondria and the autophagy-inflammation-cell death axis in organismal aging Emerging functional cross-talk between the Keap1-Nrf2 system and mitochondria Glutathione: new roles in redox signaling for an old antioxidant Mitochondrial dynamics and mitophagy in Parkinson's disease: disordered cellular power plant becomes a big deal in a major movement disorder Ageing and Parkinson's disease: why is advancing age the biggest risk factor?The role of autophagy in Parkinson's disease Oxidative Stress in Caenorhabditis elegans: Protective Effects of Spartin Oxidative stress in Alzheimer's and Parkinson's diseases: insights from the yeast Saccharomyces cerevisiae Dysregulation of autophagy and mitochondrial function in Parkinson's disease LRRK2 at the interface of autophagosomes, endosomes and lysosomes Serotonin 1A Receptors on Astrocytes as a Potential Target for the Treatment of Parkinson's Disease Anti-Oxidants in Parkinson's Disease Therapy: A Critical Point of View Autophagosome dynamics in neurodegeneration at a glance ATP13A2 regulates mitochondrial bioenergetics through macroautophagy Evidence for a common biological pathway linking three Parkinson's disease-causing genes: parkin, PINK1 and DJ-1 Mitochondrial defects and oxidative stress in Alzheimer disease and Parkinson disease The p.L302P mutation in the lysosomal enzyme gene SMPD1 is a risk factor for Parkinson disease Mitophagy mechanisms and role in human diseases Beyond mitophagy: cytosolic PINK1 as a messenger of mitochondrial health DJ-1 knock-down impairs astrocyte mitochondrial function.Identification of glutathione (GSH)-independent glyoxalase III from Schizosaccharomyces pombe.Redox regulation of antioxidants, autophagy, and the response to stress: implications for electrophile therapeutics.Mitochondrial disorders and the eye.

P2860

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P2860

DJ-1 acts in parallel to the PINK1/parkin pathway to control mitochondrial function and autophagy.

http://www.wikidata.org/entity/Q34399382

description

2010 nî lūn-bûn

@nan

2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

DJ-1 acts in parallel to the P ...... ndrial function and autophagy.

@ast

DJ-1 acts in parallel to the P ...... ndrial function and autophagy.

@en

DJ-1 acts in parallel to the P ...... ndrial function and autophagy.

@nl

type

label

DJ-1 acts in parallel to the P ...... ndrial function and autophagy.

@ast

DJ-1 acts in parallel to the P ...... ndrial function and autophagy.

@en

DJ-1 acts in parallel to the P ...... ndrial function and autophagy.

@nl

prefLabel

DJ-1 acts in parallel to the P ...... ndrial function and autophagy.

@ast

DJ-1 acts in parallel to the P ...... ndrial function and autophagy.

@en

DJ-1 acts in parallel to the P ...... ndrial function and autophagy.

@nl

P1433

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P2860

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P932

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P1433

Human Molecular Genetics

P1476

DJ-1 acts in parallel to the P ...... ndrial function and autophagy.

@en

P2093

Alexandra Beilina

http://www.w3.org/2001/XMLSchema#string

Anna Sandebring

http://www.w3.org/2001/XMLSchema#string

David Miller

http://www.w3.org/2001/XMLSchema#string

Dragan Maric

http://www.w3.org/2001/XMLSchema#string

Jeff Blackinton

http://www.w3.org/2001/XMLSchema#string

Kelly Jean Thomas

http://www.w3.org/2001/XMLSchema#string

Marcel van der Brug

http://www.w3.org/2001/XMLSchema#string

Melissa K McCoy

http://www.w3.org/2001/XMLSchema#string

P2860

PINK1 is selectively stabilized on impaired mitochondria to activate Parkin

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1

PINK1 is recruited to mitochondria with parkin and associates with LC3 in mitophagy

Mutations in PTEN-induced putative kinase 1 associated with recessive parkinsonism have differential effects on protein stability

Mitochondrial localization of the Parkinson's disease related protein DJ-1: implications for pathogenesis

DJ-1 has a role in antioxidative stress to prevent cell death

Parkin, PINK1, and DJ-1 form a ubiquitin E3 ligase complex promoting unfolded protein degradation

RNA binding activity of the recessive parkinsonism protein DJ-1 supports involvement in multiple cellular pathways

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

P304

40-50

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scholarly article

P356

10.1093/HMG/DDQ430

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P433

1

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P478

20

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P50

Angel Cedazo-Minguez

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2010-10-11T00:00:00Z

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P5875

47403494

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20940149

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P921

P932

3000675

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