Anti-tumor activity of splice-switching oligonucleotides. - Wikidata - wikimedia - TriplyDB

Anti-tumor activity of splice-switching oligonucleotides.

Anti-tumor activity of splice-switching oligonucleotides.

http://www.wikidata.org/entity/Q34401490

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The transcription factor FBI-1 inhibits SAM68-mediated BCL-X alternative splicing and apoptosis The RNA helicase A in malignant transformation Splicing Regulation: A Molecular Device to Enhance Cancer Cell Adaptation SAM68: Signal Transduction and RNA Metabolism in Human Cancer Potential molecular targeting of splice variants for cancer treatment Long non-coding RNA INXS is a critical mediator of BCL-XS induced apoptosis Silencing disease genes in the laboratory and the clinic Alternative splicing promotes tumour aggressiveness and drug resistance in African American prostate cancer.The splicing factor RBM4 controls apoptosis, proliferation, and migration to suppress tumor progression.Antisense Modulation of RNA Processing as a Therapeutic Approach in Cancer Therapy.Characterization of biomolecular nanoconjugates by high-throughput delivery and spectroscopic difference.High-throughput screening identifies small molecules that enhance the pharmacological effects of oligonucleotides.Antitumorigenic potential of STAT3 alternative splicing modulation Group VIA Phospholipase A2 (iPLA2β) Modulates Bcl-x 5'-Splice Site Selection and Suppresses Anti-apoptotic Bcl-x(L) in β-Cells.mRNA transcript diversity creates new opportunities for pharmacological intervention.The Proto-oncogene PKCι regulates the alternative splicing of Bcl-x pre-mRNA.The Splicing Efficiency of Activating HRAS Mutations Can Determine Costello Syndrome Phenotype and Frequency in Cancer Mcl-1 involvement in mitochondrial dynamics is associated with apoptotic cell death Tuning of alternative splicing--switch from proto-oncogene to tumor suppressor The small molecule Retro-1 enhances the pharmacological actions of antisense and splice switching oligonucleotides.Targeting RNA splicing for disease therapy.Directing HER4 mRNA expression towards the CYT2 isoform by antisense oligonucleotide decreases growth of breast cancer cells in vitro and in vivo.Clinical Significance of HER-2 Splice Variants in Breast Cancer Progression and Drug Resistance.Modulation of Bcl-x Alternative Splicing Induces Apoptosis of Human Hepatic Stellate Cells.Induction of antagonistic soluble decoy receptor tyrosine kinases by intronic polyA activation.Splice-switching antisense oligonucleotides as therapeutic drugs Oncogenic alternative splicing switches: role in cancer progression and prospects for therapy.Lipid nanoparticles for cancer therapy: state of the art and future prospects.Alternative splicing programs in prostate cancer.Pre-mRNA splicing in cancer: the relevance in oncogenesis, treatment and drug resistance.BCLAF1 and its splicing regulator SRSF10 regulate the tumorigenic potential of colon cancer cells.Aptamer-mediated delivery of splice-switching oligonucleotides to the nuclei of cancer cells.Dendritic nanoconjugates for intracellular delivery of neutral oligonucleotides A high-throughput screening assay for the functional delivery of splice-switching oligonucleotides in human melanoma cells.Direct oligonucleotide-photosensitizer conjugates for photochemical delivery of antisense oligonucleotides.The CRISPR/Cas system inhibited the pro-oncogenic effects of alternatively spliced fibronectin extra domain A via editing the genome in salivary adenoid cystic carcinoma cells.Regulation of BCL-X splicing reveals a role for the polypyrimidine tract binding protein (PTBP1/hnRNP I) in alternative 5' splice site selection.Alternative splicing and cell survival: from tissue homeostasis to disease.Albumin-based nanoconjugates for targeted delivery of therapeutic oligonucleotides Targeting Splicing in the Treatment of Human Disease

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Anti-tumor activity of splice-switching oligonucleotides.

http://www.wikidata.org/entity/Q34401490

description

2010 nî lūn-bûn

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2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի օգոստոսին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Anti-tumor activity of splice-switching oligonucleotides.

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Anti-tumor activity of splice-switching oligonucleotides.

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Anti-tumor activity of splice-switching oligonucleotides.

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type

label

Anti-tumor activity of splice-switching oligonucleotides.

@ast

Anti-tumor activity of splice-switching oligonucleotides.

@en

Anti-tumor activity of splice-switching oligonucleotides.

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prefLabel

Anti-tumor activity of splice-switching oligonucleotides.

@ast

Anti-tumor activity of splice-switching oligonucleotides.

@en

Anti-tumor activity of splice-switching oligonucleotides.

@nl

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Anti-tumor activity of splice-switching oligonucleotides.

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Angela Yang

http://www.w3.org/2001/XMLSchema#string

John A Bauman

http://www.w3.org/2001/XMLSchema#string

Leaf Huang

http://www.w3.org/2001/XMLSchema#string

P2860

bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death

Nuclear antisense effects of neutral, anionic and cationic oligonucleotide analogs

Restoration of correct splicing in thalassemic pre-mRNA by antisense oligonucleotides

Local restoration of dystrophin expression with the morpholino oligomer AVI-4658 in Duchenne muscular dystrophy: a single-blind, placebo-controlled, dose-escalation, proof-of-concept study

Alternative isoform regulation in human tissue transcriptomes

An inhibitor of Bcl-2 family proteins induces regression of solid tumours

RNA and disease

Cationic PMMA nanoparticles bind and deliver antisense oligoribonucleotides allowing restoration of dystrophin expression in the mdx mouse

Are splicing mutations the most frequent cause of hereditary disease?

Repair of thalassemic human beta-globin mRNA in mammalian cells by antisense oligonucleotides

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