Inhibitor of fatty acid amide hydrolase normalizes cardiovascular function in hypertension without adverse metabolic effects
about
Chemical probes of endocannabinoid metabolismTriphasic blood pressure responses to cannabinoids: do we understand the mechanism?Amygdala FAAH and anandamide: mediating protection and recovery from stressFluoxetine Facilitates Fear Extinction Through Amygdala EndocannabinoidsInhibitors of Fatty Acid Amide Hydrolase and Monoacylglycerol Lipase: New Targets for Future AntidepressantsInhibition of FAAH and activation of PPAR: new approaches to the treatment of cognitive dysfunction and drug addictionElevating endocannabinoid levels: pharmacological strategies and potential therapeutic applicationsApproximating protein flexibility through dynamic pharmacophore models: application to fatty acid amide hydrolase (FAAH)Fatty-acid-binding protein inhibition produces analgesic effects through peripheral and central mechanisms.Activation of the Nlrp3 inflammasome in infiltrating macrophages by endocannabinoids mediates beta cell loss in type 2 diabetes.Peripheral cannabinoid-1 receptor inverse agonism reduces obesity by reversing leptin resistance.Sulfonyl fluoride inhibitors of fatty acid amide hydrolase.Phytoestrogens enhance the vascular actions of the endocannabinoid anandamide in mesenteric beds of female ratsInhibiting fatty acid amide hydrolase normalizes endotoxin-induced enhanced gastrointestinal motility in mice.The novel, orally available and peripherally restricted selective cannabinoid CB2 receptor agonist LEI-101 prevents cisplatin-induced nephrotoxicity.Convergent translational evidence of a role for anandamide in amygdala-mediated fear extinction, threat processing and stress-reactivityThe endocannabinoid 2-arachidonoylglycerol mediates D1 and D2 receptor cooperative enhancement of rat nucleus accumbens core neuron firing.Effects of fatty acid amide hydrolase (FAAH) inhibitors on working memory in rats.Modulating the endocannabinoid system in human health and disease--successes and failuresHybrid inhibitor of peripheral cannabinoid-1 receptors and inducible nitric oxide synthase mitigates liver fibrosisMonounsaturated fatty acids generated via stearoyl CoA desaturase-1 are endogenous inhibitors of fatty acid amide hydrolase.Investigational drugs under development for the treatment of PTSD.Sulfonyl fluorides as privileged warheads in chemical biologyCB1 receptor activation in the rat paraventricular nucleus induces bi-directional cardiovascular effects via modification of glutamatergic and GABAergic neurotransmission.Redox system and phospholipid metabolism in the kidney of hypertensive rats after FAAH inhibitor URB597 administration.Chronic inhibition of fatty acid amide hydrolase by URB597 produces differential effects on cardiac performance in normotensive and hypertensive rats.Anandamide and endocannabinoid system: an attractive therapeutic approach for cardiovascular disease.The Effect of Long-Term Administration of Fatty Acid Amide Hydrolase Inhibitor URB597 on Oxidative Metabolism in the Heart of Rats with Primary and Secondary Hypertension
P2860
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P2860
Inhibitor of fatty acid amide hydrolase normalizes cardiovascular function in hypertension without adverse metabolic effects
description
2010 nî lūn-bûn
@nan
2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Inhibitor of fatty acid amide ...... hout adverse metabolic effects
@ast
Inhibitor of fatty acid amide ...... hout adverse metabolic effects
@en
Inhibitor of fatty acid amide ...... hout adverse metabolic effects
@nl
type
label
Inhibitor of fatty acid amide ...... hout adverse metabolic effects
@ast
Inhibitor of fatty acid amide ...... hout adverse metabolic effects
@en
Inhibitor of fatty acid amide ...... hout adverse metabolic effects
@nl
prefLabel
Inhibitor of fatty acid amide ...... hout adverse metabolic effects
@ast
Inhibitor of fatty acid amide ...... hout adverse metabolic effects
@en
Inhibitor of fatty acid amide ...... hout adverse metabolic effects
@nl
P2093
P2860
P50
P1476
Inhibitor of fatty acid amide ...... hout adverse metabolic effects
@en
P2093
Bani Mukhopadhyay
George Kunos
Grzegorz Godlewski
Jacqueline L Blankman
Joseph Tam
Judith Harvey-White
László Offertáler
Shakiru O Alapafuja
Spyros P Nikas
P2860
P304
P356
10.1016/J.CHEMBIOL.2010.08.013
P577
2010-11-01T00:00:00Z