Cyclophilin A and TRIM5alpha independently regulate human immunodeficiency virus type 1 infectivity in human cells
about
TRIM5 is an innate immune sensor for the retrovirus capsid latticeInhibition of human immunodeficiency virus type 1 replication in human cells by Debio-025, a novel cyclophilin binding agentCross-Species Virus Transmission and the Emergence of New Epidemic DiseasesHepatitis C Virus NS5A Protein Is a Substrate for the Peptidyl-prolyl cis/trans Isomerase Activity of Cyclophilins A and BThe three-dimensional structure of two redox states of cyclophilin A from Schistosoma mansoni. Evidence for redox regulation of peptidyl-prolyl cis-trans isomerase activityRestriction of HIV-1 replication in monocytes is abolished by Vpx of SIVsmmPBjGene expression analysis of a panel of cell lines that differentially restrict HIV-1 CA mutants infection in a cyclophilin a-dependent mannerLv4 Is a Capsid-Specific Antiviral Activity in Human Blood Cells That Restricts Viruses of the SIVMAC/SIVSM/HIV-2 Lineage Prior to IntegrationEvolution of a TRIM5-CypA splice isoform in old world monkeysRegulatory polymorphisms in the cyclophilin A gene, PPIA, accelerate progression to AIDS.Interfering residues narrow the spectrum of MLV restriction by human TRIM5alpha.FIV Gag: virus assembly and host-cell interactions.Cyclosporine blocks incorporation of HIV-1 envelope glycoprotein into virions.Expression patterns and action analysis of genes associated with hepatitis virus infection during rat liver regeneration.Rapamycin relieves lentiviral vector transduction resistance in human and mouse hematopoietic stem cells.A TRIM5alpha exon 2 polymorphism is associated with protection from HIV-1 infection in the Pumwani sex worker cohort.Multiple sites in the N-terminal half of simian immunodeficiency virus capsid protein contribute to evasion from rhesus monkey TRIM5α-mediated restriction.The carboxyl-terminus of human immunodeficiency virus type 2 circulating recombinant form 01_AB capsid protein affects sensitivity to human TRIM5α.Delaying reverse transcription does not increase sensitivity of HIV-1 to human TRIM5α.Homology-based identification of capsid determinants that protect HIV1 from human TRIM5α restrictionModulation of TRIM5alpha activity in human cells by alternatively spliced TRIM5 isoforms.Role of TRIM5α RING domain E3 ubiquitin ligase activity in capsid disassembly, reverse transcription blockade, and restriction of simian immunodeficiency virus.Cyclophilin A, TRIM5, and resistance to human immunodeficiency virus type 1 infectionTRIM5 structure, HIV-1 capsid recognition, and innate immune signalingVif counteracts a cyclophilin A-imposed inhibition of simian immunodeficiency viruses in human cells.Host factors influencing susceptibility to HIV infection and AIDS progression.Cell factors stimulate human immunodeficiency virus type 1 reverse transcription in vitroRelief of preintegration inhibition and characterization of additional blocks for HIV replication in primary mouse T cells.Identification of HIV inhibitors guided by free energy perturbation calculations.Innate immune sensing of HIV-1 by dendritic cells.The control of viral infection by tripartite motif proteins and cyclophilin A.Correlation of naturally occurring HIV-1 resistance to DEB025 with capsid amino acid polymorphismsHeterogeneous susceptibility of circulating SIV isolate capsids to HIV-interacting factorsModulation of HIV-1 infectivity and cyclophilin A-dependence by Gag sequence and target cell typePressure from TRIM5α contributes to control of HIV-1 replication by individuals expressing protective HLA-B alleles.An invariant surface patch on the TRIM5alpha PRYSPRY domain is required for retroviral restriction but dispensable for capsid binding.Potent inhibition of HIV-1 by TRIM5-cyclophilin fusion proteins engineered from human componentsHuman cellular restriction factors that target HIV-1 replication.Cyclophilin A promotes HIV-1 reverse transcription but its effect on transduction correlates best with its effect on nuclear entry of viral cDNA.Gene therapy strategies to exploit TRIM derived restriction factors against HIV-1.
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P2860
Cyclophilin A and TRIM5alpha independently regulate human immunodeficiency virus type 1 infectivity in human cells
description
2006 nî lūn-bûn
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2006 թուականի Մարտին հրատարակուած գիտական յօդուած
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2006 թվականի մարտին հրատարակված գիտական հոդված
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2006年の論文
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2006年論文
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2006年論文
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2006年論文
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2006年論文
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2006年論文
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2006年论文
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name
Cyclophilin A and TRIM5alpha i ...... e 1 infectivity in human cells
@ast
Cyclophilin A and TRIM5alpha i ...... e 1 infectivity in human cells
@en
Cyclophilin A and TRIM5alpha i ...... e 1 infectivity in human cells
@nl
type
label
Cyclophilin A and TRIM5alpha i ...... e 1 infectivity in human cells
@ast
Cyclophilin A and TRIM5alpha i ...... e 1 infectivity in human cells
@en
Cyclophilin A and TRIM5alpha i ...... e 1 infectivity in human cells
@nl
prefLabel
Cyclophilin A and TRIM5alpha i ...... e 1 infectivity in human cells
@ast
Cyclophilin A and TRIM5alpha i ...... e 1 infectivity in human cells
@en
Cyclophilin A and TRIM5alpha i ...... e 1 infectivity in human cells
@nl
P2860
P1433
P1476
Cyclophilin A and TRIM5alpha i ...... e 1 infectivity in human cells
@en
P2093
Elena Sokolskaja
Lionel Berthoux
P2860
P304
P356
10.1128/JVI.80.6.2855-2862.2006
P407
P50
P577
2006-03-01T00:00:00Z