WNK3 bypasses the tonicity requirement for K-Cl cotransporter activation via a phosphatase-dependent pathway - Wikidata - wikimedia - TriplyDB

WNK3 bypasses the tonicity requirement for K-Cl cotransporter activation via a phosphatase-dependent pathway

WNK3 bypasses the tonicity requirement for K-Cl cotransporter activation via a phosphatase-dependent pathway

http://www.wikidata.org/entity/Q34478816

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Similar effects of all WNK3 variants on SLC12 cotransporters WNK3 positively regulates epithelial calcium channels TRPV5 and TRPV6 via a kinase-dependent pathway WNK2 kinase is a novel regulator of essential neuronal cation-chloride cotransporters The WNK-regulated SPAK/OSR1 kinases directly phosphorylate and inhibit the K+-Cl- co-transporters SLC26A9 is a Cl(-) channel regulated by the WNK kinases The thiazide-sensitive Na+-Cl- cotransporter: molecular biology, functional properties, and regulation by WNKs WNK3 and WNK4 amino-terminal domain defines their effect on the renal Na+-Cl- cotransporter Renal and brain isoforms of WNK3 have opposite effects on NCCT expression WNK1 and OSR1 regulate the Na+, K+, 2Cl- cotransporter in HeLa cells Expanding Spectrum of Sodium Potassium Chloride Co-transporters in the Pathophysiology of Diseases K-Cl cotransporters, cell volume homeostasis, and neurological disease Modulation of neuronal activity by phosphorylation of the K-Cl cotransporter KCC2 Current view on the functional regulation of the neuronal K(+)-Cl(-) cotransporter KCC2 Identification of the WNK-SPAK/OSR1 signaling pathway in rodent and human lenses Sites of regulated phosphorylation that control K-Cl cotransporter activity Cell-type specific distribution of chloride transporters in the rat suprachiasmatic nucleus.Molecular components of signal amplification in olfactory sensory cilia.Opposite temperature effect on transport activity of KCC2/KCC4 and N(K)CCs in HEK-293 cells Regulation of with-no-lysine kinase signaling by Kelch-like proteins.LINGO-1 receptor promotes neuronal apoptosis by inhibiting WNK3 kinase activity.Altered expression of regulators of the cortical chloride transporters NKCC1 and KCC2 in schizophrenia.The WNKs: atypical protein kinases with pleiotropic actions.WNK4-mediated regulation of renal ion transport proteins.Cation-chloride cotransporters in neuronal development, plasticity and disease Role of an apical K,Cl cotransporter in urine formation by renal tubules of the yellow fever mosquito (Aedes aegypti).Aldosterone modulates thiazide-sensitive sodium chloride cotransporter abundance via DUSP6-mediated ERK1/2 signaling pathway.Potassium excretion during antinatriuresis: perspective from a distal nephron model.Inhibition of WNK3 Kinase Signaling Reduces Brain Damage and Accelerates Neurological Recovery After Stroke.A minor role of WNK3 in regulating phosphorylation of renal NKCC2 and NCC co-transporters in vivo Regulation of NKCC2 by a chloride-sensing mechanism involving the WNK3 and SPAK kinases.Limitations of Current GABA Agonists in Neonatal Seizures: Toward GABA Modulation Via the Targeting of Neuronal Cl(-) Transport.GABA(A) receptors in normal development and seizures: friends or foes?Hypertension: the missing WNKs.Endocannabinoid signaling enhances visual responses through modulation of intracellular chloride levels in retinal ganglion cells.Molecular evidence for a role for K(+)-Cl(-) cotransporters in the kidney.Phosphoregulation of the Na-K-2Cl and K-Cl cotransporters by the WNK kinases.Cell volume homeostatic mechanisms: effectors and signalling pathways.Aldosterone paradox: differential regulation of ion transport in distal nephron.WNK3 is a putative chloride-sensing kinase.The WNK-SPAK/OSR1 pathway: master regulator of cation-chloride cotransporters.

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P2860

WNK3 bypasses the tonicity requirement for K-Cl cotransporter activation via a phosphatase-dependent pathway

http://www.wikidata.org/entity/Q34478816

description

2006 nî lūn-bûn

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2006 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2006年の論文

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2006年論文

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name

WNK3 bypasses the tonicity req ...... phosphatase-dependent pathway

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WNK3 bypasses the tonicity req ...... phosphatase-dependent pathway

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WNK3 bypasses the tonicity req ...... phosphatase-dependent pathway

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type

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WNK3 bypasses the tonicity req ...... phosphatase-dependent pathway

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WNK3 bypasses the tonicity req ...... phosphatase-dependent pathway

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WNK3 bypasses the tonicity req ...... phosphatase-dependent pathway

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WNK3 bypasses the tonicity req ...... phosphatase-dependent pathway

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WNK3 bypasses the tonicity req ...... phosphatase-dependent pathway

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WNK3 bypasses the tonicity req ...... phosphatase-dependent pathway

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Proceedings of the National Academy of Sciences of the United States of America

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WNK3 bypasses the tonicity req ...... phosphatase-dependent pathway

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David B Mount

http://www.w3.org/2001/XMLSchema#string

Jesse Rinehart

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Kristopher T Kahle

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Norma A Bobadilla

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Norma Vázquez

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Paola de Los Heros

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Pedro San Cristobal

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Richard P Lifton

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Steven C Hebert

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P2860

Cloning and characterization of KCC3 and KCC4, new members of the cation-chloride cotransporter gene family

WNK3 kinase is a positive regulator of NKCC2 and NCC, renal cation-Cl- cotransporters required for normal blood pressure homeostasis

Molecular, functional, and genomic characterization of human KCC2, the neuronal K-Cl cotransporter

NH2-terminal heterogeneity in the KCC3 K+-Cl- cotransporter

Molecular pathogenesis of inherited hypertension with hyperkalemia: the Na-Cl cotransporter is inhibited by wild-type but not mutant WNK4

The Na-K-Cl cotransporter of secretory epithelia

Protein phosphatase 1--targeted in many directions

Molecular physiology of cation-coupled Cl- cotransport: the SLC12 family

Regulation of WNK1 by an autoinhibitory domain and autophosphorylation

Human hypertension caused by mutations in WNK kinases

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