Discovery of a novel pharmacological and structural class of gamma secretase modulators derived from the extract of Actaea racemosa.

Discovery of a novel pharmacological and structural class of gamma secretase modulators derived from the extract of Actaea racemosa.

Item
http://www.wikidata.org/entity/Q34498158
Targeting the γ-/β-secretase interaction reduces β-amyloid generation and ameliorates Alzheimer's disease-related pathogenesisNew anti-angiogenic leading structure discovered in the fruit of Cimicifuga yunnanensisThe FDA-approved natural product dihydroergocristine reduces the production of the Alzheimer's disease amyloid-β peptidesEfficacy of SPI-1865, a novel gamma-secretase modulator, in multiple rodent models.Matching the power of high throughput screening to the chemical diversity of natural productsDevelopment and mechanism of γ-secretase modulators for Alzheimer's disease.Novel γ-secretase modulators for the treatment of Alzheimer's disease: a review focusing on patents from 2010 to 2012.Current pharmacotherapy and putative disease-modifying therapy for Alzheimer's disease.The structural modification of natural products for novel drug discovery.Initial Optimization of a New Series of γ-Secretase Modulators Derived from a Triterpene GlycosideNatural Product and Natural Product-Derived Gamma Secretase Modulators from Actaea Racemosa Extracts.γ-Secretase Modulators: Can We Combine Potency with Safety?Modulation of gamma-secretase for the treatment of Alzheimer's disease.Black cohosh improves objective sleep in postmenopausal women with sleep disturbance.Structural and Chemical Biology of Presenilin Complexes.
P2860

Discovery of a novel pharmacological and structural class of gamma secretase modulators derived from the extract of Actaea racemosa.

Item
http://www.wikidata.org/entity/Q34498158
description
2012 nî lūn-bûn
@nan
2012 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2012年の論文
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2012年論文
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2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
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name
Discovery of a novel pharmacol ...... he extract of Actaea racemosa.
@ast
Discovery of a novel pharmacol ...... he extract of Actaea racemosa.
@en
Discovery of a novel pharmacol ...... he extract of Actaea racemosa.
@nl
type
label
Discovery of a novel pharmacol ...... he extract of Actaea racemosa.
@ast
Discovery of a novel pharmacol ...... he extract of Actaea racemosa.
@en
Discovery of a novel pharmacol ...... he extract of Actaea racemosa.
@nl
prefLabel
Discovery of a novel pharmacol ...... he extract of Actaea racemosa.
@ast
Discovery of a novel pharmacol ...... he extract of Actaea racemosa.
@en
Discovery of a novel pharmacol ...... he extract of Actaea racemosa.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P5875
P698
P921
P932
P356
P1433
P1476
Discovery of a novel pharmacol ...... he extract of Actaea racemosa.
@en
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P5875
P698
P921
P932