Regulation of cyp3a gene transcription by the pregnane x receptor.
about
The biological actions of dehydroepiandrosterone involves multiple receptorsThe evolution of drug-activated nuclear receptors: one ancestral gene diverged into two xenosensor genes in mammalsTandem machine learning for the identification of genes regulated by transcription factors.Japanese-US common-arm analysis of paclitaxel plus carboplatin in advanced non-small-cell lung cancer: a model for assessing population-related pharmacogenomics.Impact of the herbal medicine Sophora flavescens on the oral pharmacokinetics of indinavir in rats: the involvement of CYP3A and P-glycoproteinPAS kinase is required for normal cellular energy balancePregnane X receptor and natural products: beyond drug-drug interactionsGenetic variability in CYP3A5 and its possible consequences.Functional evolution of the vitamin D and pregnane X receptors.Active nuclear receptors exhibit highly correlated AF-2 domain motionsPharmacokinetic interactions of drugs with St John's wort.Activation of the steroid and xenobiotic receptor, SXR, induces apoptosis in breast cancer cellsIdentification of clinically used drugs that activate pregnane X receptorsSt. John's Wort Has Metabolically Favorable Effects on Adipocytes In Vivo.Alpha-Tocopherol Transfer Protein (alpha-TTP): Insights from Alpha-Tocopherol Transfer Protein Knockout Mice.Development of a common carp (Cyprinus carpio) pregnane X receptor (cPXR) transactivation reporter assay and its activation by azole fungicides and pharmaceutical chemicals.Potential of an in vitro toolbox combined with exposure data as a first step for the risk assessment of dietary chemical contaminants.The far and distal enhancers in the CYP3A4 gene co-ordinate the proximal promoter in responding similarly to the pregnane X receptor but differentially to hepatocyte nuclear factor-4alphaDexamethasone transcriptionally increases the expression of the pregnane X receptor and synergistically enhances pyrethroid esfenvalerate in the induction of cytochrome P450 3A23.Regulation of a xenobiotic sulfonation cascade by nuclear pregnane X receptor (PXR).Herbal modulation of P-glycoprotein.The mycoestrogen zearalenone induces CYP3A through activation of the pregnane X receptor.The Chinese herbal medicine Sophora flavescens activates pregnane X receptorIdentification of bile acid precursors as endogenous ligands for the nuclear xenobiotic pregnane X receptor.St. John's Wort inhibits adipocyte differentiation and induces insulin resistance in adipocytes.Cytochrome P450 and xenobiotic receptor humanized mice.Nuclear receptors. I. Nuclear receptors and bile acid homeostasis.Rifampicin induction of CYP3A4 requires pregnane X receptor cross talk with hepatocyte nuclear factor 4alpha and coactivators, and suppression of small heterodimer partner gene expression.Role of pregnane X receptor and aryl hydrocarbon receptor in transcriptional regulation of pxr, CYP2, and CYP3 genes in developing zebrafish.Targeting the pregnane X receptor in liver injury.Identification of genes controlled by the pregnane X receptor by microarray analysis of mRNAs from pregnenolone 16alpha-carbonitrile-treated rats.Drug-activated nuclear receptors CAR and PXR.Phenytoin induction of the cyp2c37 gene is mediated by the constitutive androstane receptor.Identification of promoter polymorphisms in the cytochrome P450 CYP6AY1 linked with insecticide resistance in the brown planthopper, Nilaparvata lugens.α-Tocopherol injections in rats up-regulate hepatic ABC transporters, but not cytochrome P450 enzymesIntrinsic sexually dimorphic expression of the principal human CYP3A4 correlated with suboptimal activation of GH/glucocorticoid-dependent transcriptional pathways in men.Intronic polymorphism in CYP3A4 affects hepatic expression and response to statin drugsOntogeny of rdh9 (Crad3) expression: ablation causes changes in retinoid and steroid metabolizing enzymes, but RXR and androgen signaling seem normalSt. John's Wort inhibits insulin signaling in murine and human adipocytes.CYP3A5 phenotype-genotype correlations in a British population.
P2860
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P2860
Regulation of cyp3a gene transcription by the pregnane x receptor.
description
2002 nî lūn-bûn
@nan
2002 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Regulation of cyp3a gene transcription by the pregnane x receptor.
@ast
Regulation of cyp3a gene transcription by the pregnane x receptor.
@en
Regulation of cyp3a gene transcription by the pregnane x receptor.
@nl
type
label
Regulation of cyp3a gene transcription by the pregnane x receptor.
@ast
Regulation of cyp3a gene transcription by the pregnane x receptor.
@en
Regulation of cyp3a gene transcription by the pregnane x receptor.
@nl
prefLabel
Regulation of cyp3a gene transcription by the pregnane x receptor.
@ast
Regulation of cyp3a gene transcription by the pregnane x receptor.
@en
Regulation of cyp3a gene transcription by the pregnane x receptor.
@nl
P1476
Regulation of cyp3a gene transcription by the pregnane x receptor.
@en
P2093
Bryan Goodwin
Steven A Kliewer
P356
10.1146/ANNUREV.PHARMTOX.42.111901.111051
P577
2002-01-01T00:00:00Z