The Chk1-mediated S-phase checkpoint targets initiation factor Cdc45 via a Cdc25A/Cdk2-independent mechanism. - Wikidata - wikimedia - TriplyDB

The Chk1-mediated S-phase checkpoint targets initiation factor Cdc45 via a Cdc25A/Cdk2-independent mechanism.

The Chk1-mediated S-phase checkpoint targets initiation factor Cdc45 via a Cdc25A/Cdk2-independent mechanism.

http://www.wikidata.org/entity/Q34557750

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Multiple ATR-Chk1 pathway proteins preferentially associate with checkpoint-inducing DNA substrates Cell cycle-dependent formation of Cdc45-Claspin complexes in human cells is compromized by UV-mediated DNA damage Characterization of functional domains in human Claspin Cdc7-Dbf4 and the human S checkpoint response to UVC The human Tim/Tipin complex coordinates an Intra-S checkpoint response to UV that slows replication fork displacement Checkpoint kinase 1 in DNA damage response and cell cycle regulation Roles of Chk1 in cell biology and cancer therapy A novel DNA damage response: rapid degradation of the p12 subunit of dna polymerase delta ATM and ATR activities maintain replication fork integrity during SV40 chromatin replication.Global regulation of genome duplication in eukaryotes: an overview from the epifluorescence microscope.New insights into checkpoint kinase 1 in the DNA damage response signaling network.Cell cycle-dependent mobility of Cdc45 determined in vivo by fluorescence correlation spectroscopy.PPARalpha-dependent activation of cell cycle control and DNA repair genes in hepatic nonparenchymal cells.Replication fork stalling and checkpoint activation by a PKD1 locus mirror repeat polypurine-polypyrimidine (Pu-Py) tract.Replication licensing promotes cyclin D1 expression and G1 progression in untransformed human cells.Replication licensing and the DNA damage checkpoint.The role of Dbf4/Drf1-dependent kinase Cdc7 in DNA-damage checkpoint control.Reduced expression of GINS complex members induces hallmarks of pre-malignancy in primary untransformed human cells The fork and the kinase: a DNA replication tale from a CHK1 perspective.BRCA1 is required for postreplication repair after UV-induced DNA damage Dbf4 is direct downstream target of ataxia telangiectasia mutated (ATM) and ataxia telangiectasia and Rad3-related (ATR) protein to regulate intra-S-phase checkpoint.c-Jun N-terminal kinase-mediated Rad18 phosphorylation facilitates Polη recruitment to stalled replication forks Human CST abundance determines recovery from diverse forms of DNA damage and replication stress.Effective intra-S checkpoint responses to UVC in primary human melanocytes and melanoma cell lines Cell cycle stage-specific roles of Rad18 in tolerance and repair of oxidative DNA damage Integrating S-phase checkpoint signaling with trans-lesion synthesis of bulky DNA adducts.Replication origins: determinants or consequences of nuclear organization?A neomorphic cancer cell-specific role of MAGE-A4 in trans-lesion synthesis.A novel interplay between the Fanconi anemia core complex and ATR-ATRIP kinase during DNA cross-link repair.The human intra-S checkpoint response to UVC-induced DNA damage.Differential host cell gene expression and regulation of cell cycle progression by nonstructural protein 11 of porcine reproductive and respiratory syndrome virus Combined inhibition of Wee1 and Chk1 gives synergistic DNA damage in S-phase due to distinct regulation of CDK activity and CDC45 loading.ATR: a master conductor of cellular responses to DNA replication stress.Genetic variation and DNA replication timing, or why is there late replicating DNA?Eukaryotic DNA damage checkpoint activation in response to double-strand breaks.Ubiquitin Protein Ligase Ring2 Is Involved in S-phase Checkpoint and DNA Damage in Cells Exposed to Benzo[a]pyrene.Multiple pathways can bypass the essential role of fission yeast Hsk1 kinase in DNA replication initiation.Impact of Age and Insulin-Like Growth Factor-1 on DNA Damage Responses in UV-Irradiated Human Skin.A conserved proliferating cell nuclear antigen-interacting protein sequence in Chk1 is required for checkpoint function Rad18 E3 ubiquitin ligase activity mediates Fanconi anemia pathway activation and cell survival following DNA Topoisomerase 1 inhibition.

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The Chk1-mediated S-phase checkpoint targets initiation factor Cdc45 via a Cdc25A/Cdk2-independent mechanism.

http://www.wikidata.org/entity/Q34557750

description

2006 nî lūn-bûn

@nan

2006 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2006 թվականի օգոստոսին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年论文

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name

The Chk1-mediated S-phase chec ...... 5A/Cdk2-independent mechanism.

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The Chk1-mediated S-phase chec ...... 5A/Cdk2-independent mechanism.

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The Chk1-mediated S-phase chec ...... 5A/Cdk2-independent mechanism.

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The Chk1-mediated S-phase chec ...... 5A/Cdk2-independent mechanism.

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The Chk1-mediated S-phase chec ...... 5A/Cdk2-independent mechanism.

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The Chk1-mediated S-phase chec ...... 5A/Cdk2-independent mechanism.

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The Chk1-mediated S-phase chec ...... 5A/Cdk2-independent mechanism.

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The Chk1-mediated S-phase chec ...... 5A/Cdk2-independent mechanism.

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The Chk1-mediated S-phase chec ...... 5A/Cdk2-independent mechanism.

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P1433

Journal of Biological Chemistry

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The Chk1-mediated S-phase chec ...... 5A/Cdk2-independent mechanism.

@en

P2093

Cyrus Vaziri

http://www.w3.org/2001/XMLSchema#string

Damien M Slater

http://www.w3.org/2001/XMLSchema#string

Heinz-Peter Nasheuer

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Laura R Barkley

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Mark G Alexandrow

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Peijun Liu

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Tovah Day

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Xiaohui Bi

http://www.w3.org/2001/XMLSchema#string

P2860

Human CDC45 protein binds to minichromosome maintenance 7 protein and the p70 subunit of DNA polymerase alpha

The human homolog of Saccharomyces cerevisiae Mcm10 interacts with replication factors and dissociates from nuclease-resistant nuclear structures in G(2) phase

The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis

Critical role for mouse Hus1 in an S-phase DNA damage cell cycle checkpoint

A second human Dbf4/ASK-related protein, Drf1/ASKL1, is required for efficient progression of S and M phases

Negative regulation of DNA replication by the retinoblastoma protein is mediated by its association with MCM7.

Disruption of the checkpoint kinase 1/cell division cycle 25A pathway abrogates ionizing radiation-induced S and G2 checkpoints.

Rad18 regulates DNA polymerase kappa and is required for recovery from S-phase checkpoint-mediated arrest

A requirement for MCM7 and Cdc45 in chromosome unwinding during eukaryotic DNA replication

The DNA damage response: putting checkpoints in perspective

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30631-30644

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scholarly article

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10.1074/JBC.M602982200

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P407

P433

41

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P478

281

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P577

2006-08-15T00:00:00Z

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6875657

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P698

16912045

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