Handicapped retroviral vectors efficiently transduce foreign genes into hematopoietic stem cells.
about
The use of retroviral vectors for gene therapy-what are the risks? A review of retroviral pathogenesis and its relevance to retroviral vector-mediated gene deliveryTransplantable myeloproliferative disease induced in mice by an interleukin 6 retrovirus.Development of a self-inactivating lentivirus vector.Self-inactivating lentivirus vector for safe and efficient in vivo gene delivery.Improved gene expression upon transfer of the adenosine deaminase minigene outside the transcriptional unit of a retroviral vector.Clonal contributions of small numbers of retrovirally marked hematopoietic stem cells engrafted in unirradiated neonatal W/Wv miceRhesus monkey placental transgene expression after lentiviral gene transfer into preimplantation embryos.Analysis of mammalian cell genetic regulation in situ by using retrovirus-derived "portable exons" carrying the Escherichia coli lacZ gene.A versatile and potentially general approach to the targeting of specific cell types by retroviruses: application to the infection of human cells by means of major histocompatibility complex class I and class II antigens by mouse ecotropic murine leInhibition of histone deacetylation in 293GPG packaging cell line improves the production of self-inactivating MLV-derived retroviral vectorsAn improved retroviral vector for gene transfer into undifferentiated cellsThe FIP1L1-PDGFRA fusion gene cooperates with IL-5 to induce murine hypereosinophilic syndrome (HES)/chronic eosinophilic leukemia (CEL)-like disease.Progenitor cell hyperplasia with rare development of myeloid leukemia in interleukin 11 bone marrow chimeras.Stable gammaretroviral vector expression during embryonic stem cell-derived in vitro hematopoietic development.Reducing the genotoxic potential of retroviral vectors.Improvement of avian leukosis virus (ALV)-based retrovirus vectors by using different cis-acting sequences from ALVsMock retroviral infection alters the developmental potential of murine bone marrow stem cells.A model for spontaneous B-lineage lymphomas in IgHmu-HOX11 transgenic mice.Expression of human adenosine deaminase in murine hematopoietic cells.Combinatorial incorporation of enhancer-blocking components of the chicken beta-globin 5'HS4 and human T-cell receptor alpha/delta BEAD-1 insulators in self-inactivating retroviral vectors reduces their genotoxic potential.Correction of murine hemophilia A following nonmyeloablative transplantation of hematopoietic stem cells engineered to encode an enhanced human factor VIII variant using a safety-augmented retroviral vector.Thrombopoietic potential and serial repopulating ability of murine hematopoietic stem cells constitutively expressing interleukin 11.A conditional self-inactivating retrovirus vector that uses a tetracycline-responsive expression system.Improved self-inactivating retroviral vectors derived from spleen necrosis virus.Promoter interactions in retrovirus vectors introduced into fibroblasts and embryonic stem cells.Expression of retrovirally transduced IL-1 alpha in IL-6-dependent B cells: a murine model of aggressive multiple myeloma.Influence of insulators on transgene expression from integrating and non-integrating lentiviral vectors.An improved retroviral vector for assaying promoter activity. Analysis of promoter interference in pIP211 vector.Factor VIII delivered by haematopoietic stem cell-derived B cells corrects the phenotype of haemophilia A mice.
P2860
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P2860
Handicapped retroviral vectors efficiently transduce foreign genes into hematopoietic stem cells.
description
1987 nî lūn-bûn
@nan
1987 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1987 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1987年の論文
@ja
1987年論文
@yue
1987年論文
@zh-hant
1987年論文
@zh-hk
1987年論文
@zh-mo
1987年論文
@zh-tw
1987年论文
@wuu
name
Handicapped retroviral vectors ...... into hematopoietic stem cells.
@ast
Handicapped retroviral vectors ...... into hematopoietic stem cells.
@en
Handicapped retroviral vectors ...... into hematopoietic stem cells.
@nl
type
label
Handicapped retroviral vectors ...... into hematopoietic stem cells.
@ast
Handicapped retroviral vectors ...... into hematopoietic stem cells.
@en
Handicapped retroviral vectors ...... into hematopoietic stem cells.
@nl
prefLabel
Handicapped retroviral vectors ...... into hematopoietic stem cells.
@ast
Handicapped retroviral vectors ...... into hematopoietic stem cells.
@en
Handicapped retroviral vectors ...... into hematopoietic stem cells.
@nl
P2093
P2860
P356
P1476
Handicapped retroviral vectors ...... into hematopoietic stem cells.
@en
P2093
P2860
P304
P356
10.1073/PNAS.84.8.2406
P407
P577
1987-04-01T00:00:00Z