Morpholino, siRNA, and S-DNA compared: impact of structure and mechanism of action on off-target effects and sequence specificity.
about
Mammalian MagT1 and TUSC3 are required for cellular magnesium uptake and vertebrate embryonic developmentRediscovering the chick embryo as a model to study retinal developmentProteolysis of proBDNF is a key regulator in the formation of memoryRegulation of Emx2 expression by antisense transcripts in murine cortico-cerebral precursorsSilencing disease genes in the laboratory and the clinicAdvancements in zebrafish applications for 21st century toxicology.In vivo modeling of the morbid human genome using Danio rerioCytoplasmic polyadenylation and cytoplasmic polyadenylation element-dependent mRNA regulation are involved in Xenopus retinal axon development.Positional RNA-Seq identifies candidate genes for phenotypic engineering of sexual traits.Dual suppression of hemangiogenesis and lymphangiogenesis by splice-shifting morpholinos targeting vascular endothelial growth factor receptor 2 (KDR)Selective down-regulation of nuclear poly(ADP-ribose) glycohydrolase.Cell penetrating peptides in the delivery of biopharmaceuticals.Nanoparticle-mediated systemic delivery of siRNA for treatment of cancers and viral infections.Vascular Endothelial Growth Factor Receptor 1 morpholino increases graft survival in a murine penetrating keratoplasty model.Gene knockdowns in adult animals: PPMOs and vivo-morpholinos.Transient inhibition of transforming growth factor-beta1 in human diabetic CD34+ cells enhances vascular reparative functions.Synthesis of Morpholino Monomers, Chlorophosphoramidate Monomers, and Solid-Phase Synthesis of Short Morpholino Oligomers.Comparison of epigenetic mediator expression and function in mouse and human embryonic blastomeresKnockdown of mitogen-activated protein kinase (MAPK) signalling in the midgut of Anopheles stephensi mosquitoes using antisense morpholinos.Moderate hyperbilirubinemia improves renal hemodynamics in ANG II-dependent hypertensionStructure and stability of the complex formed by oligonucleotides.Photocaged morpholino oligomers for the light-regulation of gene function in zebrafish and Xenopus embryos.Phosphorodiamidate morpholino oligomers suppress mutant huntingtin expression and attenuate neurotoxicity.Fundamental role for the KCNE4 ancillary subunit in Kv7.4 regulation of arterial tone.Evidence for the requirement of 14-3-3eta (YWHAH) in meiotic spindle assembly during mouse oocyte maturation.Zebrafish guanylate cyclase type 3 signaling in cone photoreceptors.Xenopus: An emerging model for studying congenital heart disease.Reverse genetic screening reveals poor correlation between morpholino-induced and mutant phenotypes in zebrafish.Drug-Free Macromolecular Therapeutics--A New Paradigm in Polymeric NanomedicinesVascular endothelial growth factor receptor 1 morpholino decreases angiogenesis in a murine corneal suture model.E2F8 as a Novel Therapeutic Target for Lung CancerZEBRAFISH AS AN IN VIVO MODEL FOR SUSTAINABLE CHEMICAL DESIGN.Modulation of the biliary expression of arylalkylamine N-acetyltransferase alters the autocrine proliferative responses of cholangiocytes in rats.The necessity for in vivo functional analysis in human medical genetics.Design and analysis of effects of triplet repeat oligonucleotides in cell models for myotonic dystrophyMorpholino injection in Xenopus.Enzymatic mechanism of human apurinic/apyrimidinic endonuclease against a THF AP site model substrate.Zebrafish stem/progenitor factor msi2b exhibits two phases of activity mediated by different splice variants.Loss-of-function genetic tools for animal models: cross-species and cross-platform differences.Potential therapeutic applications of antisense morpholino oligonucleotides in modulation of splicing in primary immunodeficiency diseases
P2860
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P2860
Morpholino, siRNA, and S-DNA compared: impact of structure and mechanism of action on off-target effects and sequence specificity.
description
2007 nî lūn-bûn
@nan
2007 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Morpholino, siRNA, and S-DNA c ...... ects and sequence specificity.
@ast
Morpholino, siRNA, and S-DNA c ...... ects and sequence specificity.
@en
Morpholino, siRNA, and S-DNA c ...... ects and sequence specificity.
@nl
type
label
Morpholino, siRNA, and S-DNA c ...... ects and sequence specificity.
@ast
Morpholino, siRNA, and S-DNA c ...... ects and sequence specificity.
@en
Morpholino, siRNA, and S-DNA c ...... ects and sequence specificity.
@nl
prefLabel
Morpholino, siRNA, and S-DNA c ...... ects and sequence specificity.
@ast
Morpholino, siRNA, and S-DNA c ...... ects and sequence specificity.
@en
Morpholino, siRNA, and S-DNA c ...... ects and sequence specificity.
@nl
P1476
Morpholino, siRNA, and S-DNA c ...... ects and sequence specificity.
@en
P2093
James E Summerton
P304
P356
10.2174/156802607780487740
P577
2007-01-01T00:00:00Z