Identification of novel small-molecule inducers of fetal hemoglobin using pharmacophore and 'PSEUDO' receptor models.

Identification of novel small-molecule inducers of fetal hemoglobin using pharmacophore and 'PSEUDO' receptor models.

Item
http://www.wikidata.org/entity/Q34678844
Novel Inducers of Fetal Globin Identified through High Throughput Screening (HTS) Are Active In Vivo in Anemic Baboons and Transgenic MiceUltra-High-Throughput Structure-Based Virtual Screening for Small-Molecule Inhibitors of Protein-Protein Interactions.Novel therapeutic candidates, identified by molecular modeling, induce γ-globin gene expression in vivo.Erythroid Kruppel-like factor (EKLF) is recruited to the gamma-globin gene promoter as a co-activator and is required for gamma-globin gene induction by short-chain fatty acid derivativesShort-chain fatty acids induce gamma-globin gene expression by displacement of a HDAC3-NCoR repressor complex.Butyrate histone deacetylase inhibitors.Fetal globin gene inducers: novel agents and new potential.Therapeutic fetal-globin inducers reduce transcriptional repression in hemoglobinopathy erythroid progenitors through distinct mechanisms.Bioprotective carnitinoids: lipoic acid, butyrate, and mitochondria-targeting to treat radiation injury: mitochondrial drugs come of age.Controllable Mono-/Dialkenylation of Benzyl Thioethers through Rh-Catalyzed Aryl C-H Activation.
P2860

Identification of novel small-molecule inducers of fetal hemoglobin using pharmacophore and 'PSEUDO' receptor models.

Item
http://www.wikidata.org/entity/Q34678844
description
2006 nî lūn-bûn
@nan
2006 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Identification of novel small- ...... and 'PSEUDO' receptor models.
@ast
Identification of novel small- ...... and 'PSEUDO' receptor models.
@en
Identification of novel small- ...... and 'PSEUDO' receptor models.
@nl
type
label
Identification of novel small- ...... and 'PSEUDO' receptor models.
@ast
Identification of novel small- ...... and 'PSEUDO' receptor models.
@en
Identification of novel small- ...... and 'PSEUDO' receptor models.
@nl
prefLabel
Identification of novel small- ...... and 'PSEUDO' receptor models.
@ast
Identification of novel small- ...... and 'PSEUDO' receptor models.
@en
Identification of novel small- ...... and 'PSEUDO' receptor models.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P577
P5875
P698
P932
P356
P1433
P1476
Identification of novel small- ...... and 'PSEUDO' receptor models.
@en
P2093
P2860
P304
P31
P356
10.1111/J.1747-0285.2006.00386.X
P433
P478
P577
P5875
P698
P932