Activation of mTOR ameliorates fragile X premutation rCGG repeat-mediated neurodegeneration - Wikidata - wikimedia - TriplyDB

Activation of mTOR ameliorates fragile X premutation rCGG repeat-mediated neurodegeneration

Activation of mTOR ameliorates fragile X premutation rCGG repeat-mediated neurodegeneration

http://www.wikidata.org/entity/Q34693311

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Use of model systems to understand the etiology of fragile X-associated primary ovarian insufficiency (FXPOI)Fragile X-Associated Tremor/Ataxia Syndrome: From Molecular Pathogenesis to Development of Therapeutics.RAN translation at CGG repeats induces ubiquitin proteasome system impairment in models of fragile X-associated tremor ataxia syndrome Selective rescue of heightened anxiety but not gait ataxia in a premutation 90CGG mouse model of Fragile X-associated tremor/ataxia syndrome.Bone fracture in a rat femoral fracture model is associated with the activation of autophagy.Inhibition of transglutaminase exacerbates polyglutamine-induced neurotoxicity by increasing the aggregation of mutant ataxin-3 in an SCA3 Drosophila model.Of Men and Mice: Modeling the Fragile X Syndrome.

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Activation of mTOR ameliorates fragile X premutation rCGG repeat-mediated neurodegeneration

http://www.wikidata.org/entity/Q34693311

description

2013 nî lūn-bûn

@nan

2013 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2013 թվականի ապրիլին հրատարակված գիտական հոդված

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年论文

@wuu

name

Activation of mTOR ameliorates ...... eat-mediated neurodegeneration

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Activation of mTOR ameliorates ...... eat-mediated neurodegeneration

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Activation of mTOR ameliorates ...... eat-mediated neurodegeneration

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type

label

Activation of mTOR ameliorates ...... eat-mediated neurodegeneration

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Activation of mTOR ameliorates ...... eat-mediated neurodegeneration

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Activation of mTOR ameliorates ...... eat-mediated neurodegeneration

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prefLabel

Activation of mTOR ameliorates ...... eat-mediated neurodegeneration

@ast

Activation of mTOR ameliorates ...... eat-mediated neurodegeneration

@en

Activation of mTOR ameliorates ...... eat-mediated neurodegeneration

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Activation of mTOR ameliorates ...... eat-mediated neurodegeneration

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Chengyuan Tang

http://www.w3.org/2001/XMLSchema#string

Hua He

http://www.w3.org/2001/XMLSchema#string

Ranhui Duan

http://www.w3.org/2001/XMLSchema#string

P2860

Inhibition of mTOR by rapamycin abolishes cognitive deficits and reduces amyloid-beta levels in a mouse model of Alzheimer's disease

Mammalian target of rapamycin up-regulation of pyruvate kinase isoenzyme type M2 is critical for aerobic glycolysis and tumor growth

Molecular interplay between mammalian target of rapamycin (mTOR), amyloid-beta, and Tau: effects on cognitive impairments.

Rapamycin fed late in life extends lifespan in genetically heterogeneous mice

mTOR is essential for the proteotoxic stress response, HSF1 activation and heat shock protein synthesis

Fighting neurodegeneration with rapamycin: mechanistic insights

Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease

HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS

The FMR1 CGG repeat mouse displays ubiquitin-positive intranuclear neuronal inclusions; implications for the cerebellar tremor/ataxia syndrome

Activation of the mammalian target of rapamycin (mTOR) is essential for oligodendrocyte differentiation

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