Agonist-occupied A3 adenosine receptors exist within heterogeneous complexes in membrane microdomains of individual living cells.
about
Fluorescent approaches for understanding interactions of ligands with G protein coupled receptorsRecent developments in adenosine receptor ligands and their potential as novel drugsNew perspectives in signaling mediated by receptors coupled to stimulatory G protein: the emerging significance of cAMP efflux and extracellular cAMP-adenosine pathwayFluorescence correlation spectroscopy, combined with bimolecular fluorescence complementation, reveals the effects of β-arrestin complexes and endocytic targeting on the membrane mobility of neuropeptide Y receptorsFragment screening at adenosine-A(3) receptors in living cells using a fluorescence-based binding assay.Pharmacology under the microscope: the use of fluorescence correlation spectroscopy to determine the properties of ligand-receptor complexes.Antagonist selective modulation of adenosine A1 and A3 receptor pharmacology by the food dye Brilliant Black BN: evidence for allosteric interactionsFunctionalized congener approach to the design of ligands for G protein-coupled receptors (GPCRs).The effect of allosteric modulators on the kinetics of agonist-G protein-coupled receptor interactions in single living cells.Enhanced potency of nucleotide-dendrimer conjugates as agonists of the P2Y14 receptor: multivalent effect in G protein-coupled receptor recognition.Functionalized congeners of A3 adenosine receptor-selective nucleosides containing a bicyclo[3.1.0]hexane ring system.Allosteric interactions across native adenosine-A3 receptor homodimers: quantification using single-cell ligand-binding kinetics.Novel fluorescent antagonist as a molecular probe in A(3) adenosine receptor binding assays using flow cytometry.Medicinal chemistry of the A3 adenosine receptor: agonists, antagonists, and receptor engineering.Lighting up G protein-coupled purinergic receptors with engineered fluorescent ligands.Fluorescent ligands for adenosine receptors.Characterization by flow cytometry of fluorescent, selective agonist probes of the A(3) adenosine receptor.Enhanced A3 adenosine receptor selectivity of multivalent nucleoside-dendrimer conjugates.Adenosine receptors and membrane microdomainsInsights into GPCR pharmacology from the measurement of changes in intracellular cyclic AMP; advantages and pitfalls of differing methodologies.Biophysical Detection of Diversity and Bias in GPCR Function.Revealing G-protein-coupled receptor oligomerization at the single-molecule level through a nanoscopic lens: methods, dynamics and biological function.Synthesis and characterization of high-affinity 4,4-difluoro-4-bora-3a,4a-diaza-s-indacene-labeled fluorescent ligands for human β-adrenoceptors.The use of fluorescence correlation spectroscopy to characterize the molecular mobility of fluorescently labelled G protein-coupled receptors.Investigation of GPCR allosterism and dimerization in single living cells using fluorescent ligands.Influence of fluorophore and linker composition on the pharmacology of fluorescent adenosine A1 receptor ligands.A novel fluorescent histamine H(1) receptor antagonist demonstrates the advantage of using fluorescence correlation spectroscopy to study the binding of lipophilic ligands.Kinetic analysis of antagonist-occupied adenosine-A3 receptors within membrane microdomains of individual cells provides evidence of receptor dimerization and allosterism.Synthesis of BODIPY derivatives substituted with various bioconjugatable linker groups: a construction kit for fluorescent labeling of receptor ligands.A monoclonal antibody raised against a thermo-stabilised β1-adrenoceptor interacts with extracellular loop 2 and acts as a negative allosteric modulator of a sub-set of β1-adrenoceptors expressed in stable cell lines.
P2860
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P2860
Agonist-occupied A3 adenosine receptors exist within heterogeneous complexes in membrane microdomains of individual living cells.
description
2007 nî lūn-bûn
@nan
2007 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Agonist-occupied A3 adenosine ...... ns of individual living cells.
@ast
Agonist-occupied A3 adenosine ...... ns of individual living cells.
@en
Agonist-occupied A3 adenosine ...... ns of individual living cells.
@nl
type
label
Agonist-occupied A3 adenosine ...... ns of individual living cells.
@ast
Agonist-occupied A3 adenosine ...... ns of individual living cells.
@en
Agonist-occupied A3 adenosine ...... ns of individual living cells.
@nl
prefLabel
Agonist-occupied A3 adenosine ...... ns of individual living cells.
@ast
Agonist-occupied A3 adenosine ...... ns of individual living cells.
@en
Agonist-occupied A3 adenosine ...... ns of individual living cells.
@nl
P50
P356
P1433
P1476
Agonist-occupied A3 adenosine ...... ins of individual living cells
@en
P2093
Cordeaux Y
P304
P356
10.1096/FJ.07-8180COM
P407
P577
2007-10-24T00:00:00Z