Cannabinoids inhibit insulin receptor signaling in pancreatic β-cells.
about
Human β-cell proliferation and intracellular signaling: part 3Endocannabinoid regulation of β-cell functions: implications for glycaemic control and diabetesAdaptive cellular stress pathways as therapeutic targets of dietary phytochemicals: focus on the nervous systemCannabinoids, eating behaviour, and energy homeostasis.Activation of the Nlrp3 inflammasome in infiltrating macrophages by endocannabinoids mediates beta cell loss in type 2 diabetes.Cannabinoid receptor 1 gene polymorphisms and nonalcoholic Fatty liver disease in women with polycystic ovary syndrome and in healthy controlsNew insights on the role of the endocannabinoid system in the regulation of energy balance.Effects of CB1 receptor blockade on monosodium glutamate induced hypometabolic and hypothalamic obesity in rats.Gαi/o-coupled receptor signaling restricts pancreatic β-cell expansionTo be or not to be--obese.High-fat diet-induced insulin resistance does not increase plasma anandamide levels or potentiate anandamide insulinotropic effect in isolated canine isletsCannabinoid 1 receptor promotes cardiac dysfunction, oxidative stress, inflammation, and fibrosis in diabetic cardiomyopathyThe cannabinoid CB1 receptor and mTORC1 signalling pathways interact to modulate glucose homeostasis in mice.RNA-binding protein HuD controls insulin translationStructural Basis of Species-Dependent Differential Affinity of 6-Alkoxy-5-Aryl-3-Pyridinecarboxamide Cannabinoid-1 Receptor Antagonists.The endocannabinoid system and plant-derived cannabinoids in diabetes and diabetic complicationsCannabinoids Regulate Bcl-2 and Cyclin D2 Expression in Pancreatic β Cells.Blockade of β-cell K(ATP) channels by the endocannabinoid, 2-arachidonoylglycerol.Short term voluntary overfeeding disrupts brain insulin control of adipose tissue lipolysisHepatic cannabinoid receptor-1 mediates diet-induced insulin resistance via inhibition of insulin signaling and clearance in mice.Controlled downregulation of the cannabinoid CB1 receptor provides a promising approach for the treatment of obesity and obesity-derived type 2 diabetes.GIT2 Acts as a Systems-Level Coordinator of Neurometabolic Activity and Pathophysiological Aging.Cannabinoids induce pancreatic β-cell death by directly inhibiting insulin receptor activation.Pancreas++: automated quantification of pancreatic islet cells in microscopy images.Blockade of cannabinoid 1 receptor improves GLP-1R mediated insulin secretion in mice.Prolonged activation of human islet cannabinoid receptors in vitro induces adaptation but not dysfunction.Human CB1 Receptor Isoforms, present in Hepatocytes and β-cells, are Involved in Regulating MetabolismModulation of β-cell function: a translational journey from the bench to the bedside.Endocannabinoids and energy homeostasis: an update.PDE5 Inhibitor Tadalafil and Hydroxychloroquine Cotreatment Provides Synergistic Protection against Type 2 Diabetes and Myocardial Infarction in Mice.Cannabinoid 1 G protein-coupled receptor (periphero-)neutral antagonists: emerging therapeutics for treating obesity-driven metabolic disease and reducing cardiovascular risk.LH-21 and abnormal cannabidiol improve β-cell function in isolated human and mouse islets through GPR55-dependent and -independent signalling.Incretin secretion in humans is under the influence of cannabinoid receptors.Blockade of cannabinoid 1 receptor improves glucose responsiveness in pancreatic beta cells.Absence of cannabinoid 1 receptor in beta cells protects against high-fat/high-sugar diet-induced beta cell dysfunction and inflammation in murine islets.Targeted proteomics of cannabinoid receptor CB1 and the CB1b isoform.Anandamide Effects in a Streptozotocin-Induced Alzheimer's Disease-Like Sporadic Dementia in RatsGlucose Controls the Expression of Polypyrimidine Tract-Binding Protein 1 via the Insulin Receptor Signaling Pathway in Pancreatic β Cells
P2860
Q26821954-EA5E5CB0-57AC-4BB3-BC8C-F7A953B2D564Q28078897-B2A5681C-6EC4-4492-B75C-3092B9EA56C3Q28389419-6C114685-1C7B-4AC9-BA0C-FF544D51DA7AQ30357350-CC20FFA6-8BCD-48DA-99BB-D3C971CD3C92Q33731729-88401684-B252-434F-A0B6-6C41963DADB4Q34022349-A74FFC48-0712-49B3-9C54-55C50E4F2C71Q34494301-5D8145C1-D6BE-4D91-A3CA-EBFCCCA1DEAAQ34650930-32E70D76-800E-4862-8469-BF447D7EA42CQ35157007-5428D47D-69B5-435E-B66F-C44C4D2E2B22Q35223056-3FBB6006-5377-40A3-84AD-F303B47681F5Q35347646-FC286082-6722-4B47-BE3A-D70D4487AB5FQ35766956-070C09C0-9540-4156-BF35-B3F0CF1EAD0FQ35840211-ADE21B94-7FBC-47E5-8901-EC8D476376D3Q35869792-87925CCA-5661-40CC-8D29-3FE9D4389ACDQ35897867-BF75A838-5A29-40D8-B3ED-CE6EBFF04970Q35951992-88DE9151-9884-4D9B-B8DE-EECEE48EBF42Q35953952-38BA4F69-27EB-4121-9A87-88640F1EEAFEQ36160251-48C087C7-5181-47D8-BEAA-281EC16C7540Q36294800-BF1DBE54-1216-40C0-9FC2-E0E707BBEF10Q36351511-DF60C442-B62C-4121-A7A3-80A0E0E74E05Q36373581-57B4AB99-B1EC-4CAF-A6D9-167534D77481Q36471894-18E4F686-1839-4E83-9048-5DA35CA36D65Q36473356-67A16C5B-5C66-43E5-BC23-ABB18E12B2BAQ36503542-0833D59F-5D7E-4209-BC92-4AD8FC761941Q36578199-AEA67A0F-8DC8-4B9B-809F-25426F568B51Q36799355-51089B37-5267-4136-B23C-A82BD0CFC061Q37264554-FF9F4406-A248-47A3-99FD-50BE91D862D1Q38038661-7825F3B5-5723-466B-8542-59271580FD52Q38206159-F5E07EB9-0236-4D7C-82B5-1618CBCD214BQ41913523-EC1EAA13-3A87-4161-B2A0-945D3C6300FAQ45288843-333E9DF0-91A4-41D3-9FEC-E6123050FBDBQ48178388-5B96B729-C572-4D12-823A-D8823998F951Q48215464-9D813F89-369D-4EE6-AA11-E9F3DFD1EDEAQ50068640-C24A449E-6F03-4DD1-B160-4C6CEB86E232Q51246185-AB6B1AEC-70DE-4CB4-99E5-8CFD0A7322DAQ51735248-505637E7-8A8F-4CDD-ADFF-4F08D68F5FD0Q58552816-7114ACA5-77DE-4489-89A7-A62192E19F6EQ58778548-8D95606F-CF48-4737-8A23-231F7B44ADB6
P2860
Cannabinoids inhibit insulin receptor signaling in pancreatic β-cells.
description
2011 nî lūn-bûn
@nan
2011 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Cannabinoids inhibit insulin receptor signaling in pancreatic β-cells.
@ast
Cannabinoids inhibit insulin receptor signaling in pancreatic β-cells.
@en
Cannabinoids inhibit insulin receptor signaling in pancreatic β-cells.
@nl
type
label
Cannabinoids inhibit insulin receptor signaling in pancreatic β-cells.
@ast
Cannabinoids inhibit insulin receptor signaling in pancreatic β-cells.
@en
Cannabinoids inhibit insulin receptor signaling in pancreatic β-cells.
@nl
prefLabel
Cannabinoids inhibit insulin receptor signaling in pancreatic β-cells.
@ast
Cannabinoids inhibit insulin receptor signaling in pancreatic β-cells.
@en
Cannabinoids inhibit insulin receptor signaling in pancreatic β-cells.
@nl
P2093
P2860
P921
P356
P1433
P1476
Cannabinoids inhibit insulin receptor signaling in pancreatic β-cells.
@en
P2093
Bronwen Martin
Eun Kyung Lee
Hee Seung Kim
Joshua K Napora
Máire E Doyle
Olga D Carlson
Qizong Lao
Rohit N Kulkarni
Ruin Moaddel
Sam Thomas
P2860
P304
P356
10.2337/DB10-1550
P407
P577
2011-02-23T00:00:00Z