Determinants of microRNA processing inhibition by the developmentally regulated RNA-binding protein Lin28. - Wikidata - wikimedia - TriplyDB

Determinants of microRNA processing inhibition by the developmentally regulated RNA-binding protein Lin28.

Determinants of microRNA processing inhibition by the developmentally regulated RNA-binding protein Lin28.

http://www.wikidata.org/entity/Q34786272

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The tumor suppressors p53, p63, and p73 are regulators of microRNA processing complex Mammalian DIS3L2 exoribonuclease targets the uridylated precursors of let-7 miRNAs LIN-28 and the poly(U) polymerase PUP-2 regulate let-7 microRNA processing in Caenorhabditis elegans Double-negative feedback loop between reprogramming factor LIN28 and microRNA let-7 regulates aldehyde dehydrogenase 1-positive cancer stem cells The Lin28/let-7 axis regulates glucose metabolism miRNAs in human cancer Molecular basis for interaction of let-7 microRNAs with Lin28 MicroRNA let-7: an emerging next-generation cancer therapeutic Lin-28B transactivation is necessary for Myc-mediated let-7 repression and proliferation Transcription of the C. elegans let-7 microRNA is temporally regulated by one of its targets, hbl-1 Altered nuclear retention of mRNAs containing inverted repeats in human embryonic stem cells: functional role of a nuclear noncoding RNA MicroRNA: Implications for Alzheimer Disease and other Human CNS Disorders Frequency and fate of microRNA editing in human brain Let-7 and miR-200 microRNAs: guardians against pluripotency and cancer progression Lin28 recruits the TUTase Zcchc11 to inhibit let-7 maturation in mouse embryonic stem cells Interplay Between Metabolism and Oncogenic Process: Role of microRNAs The Akt-associated microRNAs MicroRNAs in the pathogenesis of cystic kidney disease The functions of microRNAs and long non-coding RNAs in embryonic and induced pluripotent stem cells MicroRNA biogenesis pathways in cancer Regulation of microRNA biogenesis and turnover by animals and their viruses Mutations in conserved residues of the C. elegans microRNA Argonaute ALG-1 identify separable functions in ALG-1 miRISC loading and target repression lin-28 controls the succession of cell fate choices via two distinct activities Structural basis of pre-let-7 miRNA recognition by the zinc knuckles of pluripotency factor Lin28 The Lin28 cold-shock domain remodels pre-let-7 microRNA Editing independent effects of ADARs on the miRNA/siRNA pathways Lin28b reprograms adult bone marrow hematopoietic progenitors to mediate fetal-like lymphopoiesis Recognition of the let-7g miRNA precursor by human Lin28B Lin28 sustains early renal progenitors and induces Wilms tumor A role for Lin28 in primordial germ-cell development and germ-cell malignancy An RNA-binding Protein, Lin28, Recognizes and Remodels G-quartets in the MicroRNAs (miRNAs) and mRNAs It Regulates Many roads to maturity: microRNA biogenesis pathways and their regulation Lin28a regulates germ cell pool size and fertility.DAZL relieves miRNA-mediated repression of germline mRNAs by controlling poly(A) tail length in zebrafish.Evidence that Lin28 stimulates translation by recruiting RNA helicase A to polysomes.Pre-miRNA loop nucleotides control the distinct activities of mir-181a-1 and mir-181c in early T cell development.Discovering ligands for a microRNA precursor with peptoid microarrays.The pluripotency factor LIN28 marks undifferentiated spermatogonia in mouse.The Human CCHC-type Zinc Finger Nucleic Acid-Binding Protein Binds G-Rich Elements in Target mRNA Coding Sequences and Promotes Translation.Oncogenic mechanisms of Lin28 in breast cancer: new functions and therapeutic opportunities.

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P2860

Determinants of microRNA processing inhibition by the developmentally regulated RNA-binding protein Lin28.

http://www.wikidata.org/entity/Q34786272

description

2008 nî lūn-bûn

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2008 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի հունիսին հրատարակված գիտական հոդված

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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name

Determinants of microRNA proce ...... ted RNA-binding protein Lin28.

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Determinants of microRNA proce ...... ted RNA-binding protein Lin28.

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Determinants of microRNA proce ...... ted RNA-binding protein Lin28.

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type

label

Determinants of microRNA proce ...... ted RNA-binding protein Lin28.

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Determinants of microRNA proce ...... ted RNA-binding protein Lin28.

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Determinants of microRNA proce ...... ted RNA-binding protein Lin28.

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Determinants of microRNA proce ...... ated RNA-binding protein Lin28

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prefLabel

Determinants of microRNA proce ...... ted RNA-binding protein Lin28.

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Determinants of microRNA proce ...... ted RNA-binding protein Lin28.

@en

Determinants of microRNA proce ...... ted RNA-binding protein Lin28.

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P1433

Journal of Biological Chemistry

P1476

Determinants of microRNA proce ...... ted RNA-binding protein Lin28.

@en

P2093

Elena Piskounova

http://www.w3.org/2001/XMLSchema#string

Maja Janas

http://www.w3.org/2001/XMLSchema#string

Richard I Gregory

http://www.w3.org/2001/XMLSchema#string

Robert J LaPierre

http://www.w3.org/2001/XMLSchema#string

P2860

The Microprocessor complex mediates the genesis of microRNAs

Localization of the developmental timing regulator Lin28 to mRNP complexes, P-bodies and stress granules

Crystal structure of human DGCR8 core

Polycistronic RNA polymerase II expression vectors for RNA interference based on BIC/miR-155.

Post-transcriptional regulation of microRNA expression

Modulation of microRNA processing and expression through RNA editing by ADAR deaminases

RNP-1, an RNA-binding motif is conserved in the DNA-binding cold shock domain

Selective blockade of microRNA processing by Lin28

Suppression of non-small cell lung tumor development by the let-7 microRNA family

Disrupting the pairing between let-7 and Hmga2 enhances oncogenic transformation

P304

21310-21314

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scholarly article

P356

10.1074/JBC.C800108200

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P433

31

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P478

283

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P50

George Q. Daley

Srinivas R Viswanathan

P577

2008-06-12T00:00:00Z

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P698

18550544

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P921