A reexamination of the nucleotide incorporation fidelity of DNA polymerases.
about
Stable complexes formed by HIV-1 reverse transcriptase at distinct positions on the primer-template controlled by binding deoxynucleoside triphosphates or foscarnetIncorporation of non-nucleoside triphosphate analogues opposite to an abasic site by human DNA polymerases beta and lambda.Best practices for evaluating single nucleotide variant calling methods for microbial genomicsA new paradigm of DNA synthesis: three-metal-ion catalysis.Mismatched dNTP incorporation by DNA polymerase does not proceed via globally different conformational pathwaysStructure-Function Relationships in Miscoding by Sulfolobus solfataricus DNA Polymerase Dpo4: GUANINE N2,N2-DIMETHYL SUBSTITUTION PRODUCES INACTIVE AND MISCODING POLYMERASE COMPLEXESWatching DNA polymerase η make a phosphodiester bondThe E295K Cancer Variant of Human Polymerase Favors the Mismatch Conformational Pathway during Nucleotide SelectionAn overview of Y-Family DNA polymerases and a case study of human DNA polymerase ηComputer simulations of protein functions: searching for the molecular origin of the replication fidelity of DNA polymerasesA water-mediated and substrate-assisted catalytic mechanism for Sulfolobus solfataricus DNA polymerase IV.Regulation of DNA repair fidelity by molecular checkpoints: "gates" in DNA polymerase beta's substrate selectionRB69 DNA polymerase structure, kinetics, and fidelity.Effect of N2-guanyl modifications on early steps in catalysis of polymerization by Sulfolobus solfataricus P2 DNA polymerase Dpo4 T239W.Structural basis for the D-stereoselectivity of human DNA polymerase β.The reopening rate of the fingers domain is a determinant of base selectivity for RB69 DNA polymerase.Effect of A and B metal ion site occupancy on conformational changes in an RB69 DNA polymerase ternary complex.Fidelity of Nucleotide Incorporation by the RNA-Dependent RNA Polymerase from Poliovirus.Nucleotide-dependent conformational change governs specificity and analog discrimination by HIV reverse transcriptase.A Change in the Rate-Determining Step of Polymerization by the K289M DNA Polymerase β Cancer-Associated VariantStructural and kinetic insights into binding and incorporation of L-nucleotide analogs by a Y-family DNA polymeraseIn silico evidence for DNA polymerase-beta's substrate-induced conformational changeIdentification of critical residues for the tight binding of both correct and incorrect nucleotides to human DNA polymerase λThe thermodynamics of template-directed DNA synthesis: base insertion and extension enthalpies.Role of a GAG hinge in the nucleotide-induced conformational change governing nucleotide specificity by T7 DNA polymerase.Remote site control of an active site fidelity checkpoint in a viral RNA-dependent RNA polymerase.DNA replication fidelity.Two proton transfers in the transition state for nucleotidyl transfer catalyzed by RNA- and DNA-dependent RNA and DNA polymerasesHow conformational dynamics of DNA polymerase select correct substrates: experiments and simulations.Viewing Human DNA Polymerase β Faithfully and Unfaithfully Bypass an Oxidative Lesion by Time-Dependent CrystallographySingle-molecule and ensemble fluorescence assays for a functionally important conformational change in T7 DNA polymerase.What a difference a decade makes: insights into translesion DNA synthesis.Fluorescence of 2-aminopurine reveals rapid conformational changes in the RB69 DNA polymerase-primer/template complexes upon binding and incorporation of matched deoxynucleoside triphosphates.Poliovirus RNA-dependent RNA polymerase (3Dpol): kinetic, thermodynamic, and structural analysis of ribonucleotide selection.Poliovirus RNA-dependent RNA polymerase (3Dpol): pre-steady-state kinetic analysis of ribonucleotide incorporation in the presence of Mn2+.Human mitochondrial RNA polymerase: evaluation of the single-nucleotide-addition cycle on synthetic RNA/DNA scaffolds.Role of induced fit in enzyme specificity: a molecular forward/reverse switch.DNA polymerases as therapeutic targetsDeep sequencing of evolving pathogen populations: applications, errors, and bioinformatic solutions.Orchestration of cooperative events in DNA synthesis and repair mechanism unraveled by transition path sampling of DNA polymerase beta's closing.
P2860
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P2860
A reexamination of the nucleotide incorporation fidelity of DNA polymerases.
description
2002 nî lūn-bûn
@nan
2002 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
A reexamination of the nucleotide incorporation fidelity of DNA polymerases.
@ast
A reexamination of the nucleotide incorporation fidelity of DNA polymerases.
@en
A reexamination of the nucleotide incorporation fidelity of DNA polymerases.
@nl
type
label
A reexamination of the nucleotide incorporation fidelity of DNA polymerases.
@ast
A reexamination of the nucleotide incorporation fidelity of DNA polymerases.
@en
A reexamination of the nucleotide incorporation fidelity of DNA polymerases.
@nl
prefLabel
A reexamination of the nucleotide incorporation fidelity of DNA polymerases.
@ast
A reexamination of the nucleotide incorporation fidelity of DNA polymerases.
@en
A reexamination of the nucleotide incorporation fidelity of DNA polymerases.
@nl
P356
P1433
P1476
A reexamination of the nucleotide incorporation fidelity of DNA polymerases.
@en
P2093
Alexander K Showalter
Ming-Daw Tsai
P304
10571-10576
P356
10.1021/BI026021I
P407
P577
2002-08-01T00:00:00Z