Poliovirus RNA-dependent RNA polymerase (3Dpol): kinetic, thermodynamic, and structural analysis of ribonucleotide selection.
about
Structural dynamics as a contributor to error-prone replication by an RNA-dependent RNA polymerase.Structure-function relationships among RNA-dependent RNA polymerasesGrowth of an RNA virus in single cells reveals a broad fitness distributionSequential structures provide insights into the fidelity of RNA replicationStructural insights into mechanisms of catalysis and inhibition in Norwalk virus polymeraseCrystal Structure of Coxsackievirus B3 3Dpol Highlights the Functional Importance of Residue 5 in Picornavirus PolymerasesStructure of Foot-and-Mouth Disease Virus Mutant Polymerases with Reduced Sensitivity to RibavirinStructural basis for active site closure by the poliovirus RNA-dependent RNA polymeraseThe Crystal Structure of a Cardiovirus RNA-Dependent RNA Polymerase Reveals an Unusual Conformation of the Polymerase Active SiteQuasispecies diversity determines pathogenesis through cooperative interactions in a viral populationFidelity of Nucleotide Incorporation by the RNA-Dependent RNA Polymerase from Poliovirus.What is the role of motif D in the nucleotide incorporation catalyzed by the RNA-dependent RNA polymerase from poliovirus?Residues of the rotavirus RNA-dependent RNA polymerase template entry tunnel that mediate RNA recognition and genome replicationRemote site control of an active site fidelity checkpoint in a viral RNA-dependent RNA polymerase.Molecular dynamics simulations of viral RNA polymerases link conserved and correlated motions of functional elements to fidelityTwo proton transfers in the transition state for nucleotidyl transfer catalyzed by RNA- and DNA-dependent RNA and DNA polymerasesStructural Analysis of Monomeric RNA-Dependent Polymerases: Evolutionary and Therapeutic ImplicationsStructure-function relationships of the viral RNA-dependent RNA polymerase: fidelity, replication speed, and initiation mechanism determined by a residue in the ribose-binding pocketHuman mitochondrial RNA polymerase: evaluation of the single-nucleotide-addition cycle on synthetic RNA/DNA scaffolds.Vaccine-derived mutation in motif D of poliovirus RNA-dependent RNA polymerase lowers nucleotide incorporation fidelity.Structural basis for proteolysis-dependent activation of the poliovirus RNA-dependent RNA polymerase.Sensitivity of the polymerase of vesicular stomatitis virus to 2' substitutions in the template and nucleotide triphosphate during initiation and elongation.RNA synthetic mechanisms employed by diverse families of RNA viruses.Cystoviral RNA-directed RNA polymerases: Regulation of RNA synthesis on multiple time and length scales.Bunyaviridae RdRps: structure, motifs, and RNA synthesis machinery.Triphosphate Reorientation of the Incoming Nucleotide as a Fidelity Checkpoint in Viral RNA-dependent RNA Polymerases.Crystal structure of complete rhinovirus RNA polymerase suggests front loading of protein primer.Determinants of RNA-dependent RNA polymerase (in)fidelity revealed by kinetic analysis of the polymerase encoded by a foot-and-mouth disease virus mutant with reduced sensitivity to ribavirin.Long-range interaction networks in the function and fidelity of poliovirus RNA-dependent RNA polymerase studied by nuclear magnetic resonance.Poliovirus polymerase residue 5 plays a critical role in elongation complex stability.Amiloride derivatives inhibit coxsackievirus B3 RNA replication.Nucleic acid polymerases use a general acid for nucleotidyl transfer.Biochemical characterization of the fidelity of poliovirus RNA-dependent RNA polymerase.Phosphorylation of viral RNA-dependent RNA polymerase and its role in replication of a plus-strand RNA virus.RNA Dependent RNA Polymerases: Insights from Structure, Function and Evolution.
P2860
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P2860
Poliovirus RNA-dependent RNA polymerase (3Dpol): kinetic, thermodynamic, and structural analysis of ribonucleotide selection.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Poliovirus RNA-dependent RNA p ...... s of ribonucleotide selection.
@ast
Poliovirus RNA-dependent RNA p ...... s of ribonucleotide selection.
@en
type
label
Poliovirus RNA-dependent RNA p ...... s of ribonucleotide selection.
@ast
Poliovirus RNA-dependent RNA p ...... s of ribonucleotide selection.
@en
prefLabel
Poliovirus RNA-dependent RNA p ...... s of ribonucleotide selection.
@ast
Poliovirus RNA-dependent RNA p ...... s of ribonucleotide selection.
@en
P2860
P356
P1433
P1476
Poliovirus RNA-dependent RNA p ...... s of ribonucleotide selection.
@en
P2093
David W Gohara
Jamie J Arnold
P2860
P304
P356
10.1021/BI035429S
P407
P577
2004-05-01T00:00:00Z