Interaction between cyclin-dependent kinases and human papillomavirus replication-initiation protein E1 is required for efficient viral replication
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Bovine papillomavirus E1 protein is sumoylated by the host cell Ubc9 proteinCell cycle-regulated phosphorylation of p220(NPAT) by cyclin E/Cdk2 in Cajal bodies promotes histone gene transcriptionReversal of growth suppression by p107 via direct phosphorylation by cyclin D1/cyclin-dependent kinase 4HIRA, the human homologue of yeast Hir1p and Hir2p, is a novel cyclin-cdk2 substrate whose expression blocks S-phase progressionThe cyclin E/Cdk2 substrate p220(NPAT) is required for S-phase entry, histone gene expression, and Cajal body maintenance in human somatic cellsThe cyclin E/Cdk2 substrate and Cajal body component p220(NPAT) activates histone transcription through a novel LisH-like domainNuclear accumulation of the papillomavirus E1 helicase blocks S-phase progression and triggers an ATM-dependent DNA damage responseRecruitment of replication protein A by the papillomavirus E1 protein and modulation by single-stranded DNAMolecular characterization, tissue tropism, and genetic variability of the novel Mupapillomavirus type HPV204 and phylogenetically related types HPV1 and HPV63.p21cip1 Degradation in differentiated keratinocytes is abrogated by costabilization with cyclin E induced by human papillomavirus E7.Mutational analysis of the Cy motif from p21 reveals sequence degeneracy and specificity for different cyclin-dependent kinases.Strategies in subversion: de-regulation of the mammalian cell cycle by viral gene products.Nuclear export of human papillomavirus type 31 E1 is regulated by Cdk2 phosphorylation and required for viral genome maintenance.The cyclin-dependent kinase inhibitor roscovitine inhibits the transactivating activity and alters the posttranslational modification of herpes simplex virus type 1 ICP0.Pharmacological cyclin-dependent kinase inhibitors inhibit replication of wild-type and drug-resistant strains of herpes simplex virus and human immunodeficiency virus type 1 by targeting cellular, not viral, proteinsIdentification of a G(2) arrest domain in the E1 wedge E4 protein of human papillomavirus type 16.Pathogenesis of human papillomaviruses in differentiating epithelia.A systems biology analysis of the changes in gene expression via silencing of HPV-18 E1 expression in HeLa cells.Small molecule inhibitors of human papillomavirus protein - protein interactions.Replication and partitioning of papillomavirus genomes.Development of quantitative and high-throughput assays of polyomavirus and papillomavirus DNA replicationInitiation of DNA replication: lessons from viral initiator proteins.Cathepsin B mediates cleavage of herpes simplex virus type 1 origin binding protein (OBP) to yield OBPC-1, and cleavage is dependent upon viral DNA replication.Novel Bovine Papillomavirus Type Discovered by Rolling-Circle Amplification Coupled with Next-Generation SequencingSynthetic lethal mutations in the cyclin A interface of human cytomegalovirusRecent advances in the search for antiviral agents against human papillomaviruses.Targeting human papillomavirus genome replication for antiviral drug discoveryHuman papillomavirus E1 helicase interacts with the WD repeat protein p80 to promote maintenance of the viral genome in keratinocytes.Virology and molecular pathogenesis of HPV (human papillomavirus)-associated oropharyngeal squamous cell carcinomaFive years of progress on cyclin-dependent kinases and other cellular proteins as potential targets for antiviral drugs.Human papillomavirus infections: warts or cancer?Analysis of coevolution in nonstructural proteins of chikungunya virus.The differential requirement for cyclin-dependent kinase activities distinguishes two functions of herpes simplex virus type 1 ICP0.The E1 proteins.Murine coronavirus nonstructural protein p28 arrests cell cycle in G0/G1 phase.Manipulation of cellular DNA damage repair machinery facilitates propagation of human papillomaviruses.Characterization of recombinant HPV6 and 11 E1 helicases: effect of ATP on the interaction of E1 with E2 and mapping of a minimal helicase domain.A Putative Cyclin-binding Motif in Human SAMHD1 Contributes to Protein Phosphorylation, Localization, and Stability.Human papillomavirus 18 E1^E4 protein interacts with cyclin A/CDK 2 through an RXL motif.Poly(A) polymerase phosphorylation is dependent on novel interactions with cyclins.
P2860
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P2860
Interaction between cyclin-dependent kinases and human papillomavirus replication-initiation protein E1 is required for efficient viral replication
description
1999 nî lūn-bûn
@nan
1999 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Interaction between cyclin-dep ...... or efficient viral replication
@ast
Interaction between cyclin-dep ...... or efficient viral replication
@en
Interaction between cyclin-dep ...... or efficient viral replication
@nl
type
label
Interaction between cyclin-dep ...... or efficient viral replication
@ast
Interaction between cyclin-dep ...... or efficient viral replication
@en
Interaction between cyclin-dep ...... or efficient viral replication
@nl
prefLabel
Interaction between cyclin-dep ...... or efficient viral replication
@ast
Interaction between cyclin-dep ...... or efficient viral replication
@en
Interaction between cyclin-dep ...... or efficient viral replication
@nl
P2093
P2860
P356
P1476
Interaction between cyclin-dep ...... or efficient viral replication
@en
P2093
P2860
P304
P356
10.1073/PNAS.96.2.382
P407
P577
1999-01-01T00:00:00Z