The cell surface glycoprotein CDCP1 in cancer--insights, opportunities, and challenges.
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The SRC-associated protein CUB Domain-Containing Protein-1 regulates adhesion and motilityInhibition of tumor metastasis: functional immune modulation of the CUB domain containing protein 1.Proteolysis-induced N-terminal ectodomain shedding of the integral membrane glycoprotein CUB domain-containing protein 1 (CDCP1) is accompanied by tyrosine phosphorylation of its C-terminal domain and recruitment of Src and PKCdelta.KAI1 suppresses HIF-1α and VEGF expression by blocking CDCP1-enhanced Src activation in prostate cancerBlocking of CDCP1 cleavage in vivo prevents Akt-dependent survival and inhibits metastatic colonization through PARP1-mediated apoptosis of cancer cells.Cellular settings mediating Src Substrate switching between focal adhesion kinase tyrosine 861 and CUB-domain-containing protein 1 (CDCP1) tyrosine 734Androgen receptor non-nuclear regulation of prostate cancer cell invasion mediated by Src and matriptase.The cell surface glycoprotein CUB domain-containing protein 1 (CDCP1) contributes to epidermal growth factor receptor-mediated cell migrationProteomic analysis of microvesicles released by the human prostate cancer cell line PC-3ADAM9 enhances CDCP1 protein expression by suppressing miR-218 for lung tumor metastasis.Phosphotyrosine recognition domains: the typical, the atypical and the versatile.CUB-domain-containing protein 1 overexpression in solid cancers promotes cancer cell growth by activating Src family kinasesDysregulated expression of cell surface glycoprotein CDCP1 in prostate cancerCell line and patient-derived xenograft models reveal elevated CDCP1 as a target in high-grade serous ovarian cancer.Cell-Surface Protein Profiling Identifies Distinctive Markers of Progenitor Cells in Human Skeletal MuscleCell surface remodeling by plasmin: a new function for an old enzyme.New crossroads for potential therapeutic intervention in cancer - intersections between CDCP1, EGFR family members and downstream signaling pathways.Elevated CDCP1 predicts poor patient outcome and mediates ovarian clear cell carcinoma by promoting tumor spheroid formation, cell migration and chemoresistance.EGF inhibits constitutive internalization and palmitoylation-dependent degradation of membrane-spanning procancer CDCP1 promoting its availability on the cell surface.Infrared spectral signatures of CDCP1-induced effects in colon carcinoma cells.Lymph node CEA and MUC2 mRNA as useful predictors of outcome in colorectal cancer.The tyrosine phosphatase SHP2 associates with CUB domain-containing protein-1 (CDCP1), regulating its expression at the cell surface in a phosphorylation-dependent mannerCD318 is a ligand for CD6.Cell-surface proteomics identifies lineage-specific markers of embryo-derived stem cells.Conditions of tumor-associated antigens as a proper target for therapeutic antibodies against solid cancers.Stratum basale keratinocyte expression of the cell-surface glycoprotein CDCP1 during epidermogenesis and its role in keratinocyte migration.Evaluation of antibodies directed against human protease-activated receptor-2.Hepatic stem cells with self-renewal and liver repopulation potential are harbored in CDCP1-positive subpopulations of human fetal liver cells.Prognostic Significance of CDCP1 Expression in Colorectal Cancer and Effect of Its Inhibition on Invasion and Migration.
P2860
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P2860
The cell surface glycoprotein CDCP1 in cancer--insights, opportunities, and challenges.
description
2009 nî lūn-bûn
@nan
2009 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
The cell surface glycoprotein CDCP1 in cancer--insights, opportunities, and challenges.
@ast
The cell surface glycoprotein CDCP1 in cancer--insights, opportunities, and challenges.
@en
The cell surface glycoprotein CDCP1 in cancer--insights, opportunities, and challenges.
@nl
type
label
The cell surface glycoprotein CDCP1 in cancer--insights, opportunities, and challenges.
@ast
The cell surface glycoprotein CDCP1 in cancer--insights, opportunities, and challenges.
@en
The cell surface glycoprotein CDCP1 in cancer--insights, opportunities, and challenges.
@nl
prefLabel
The cell surface glycoprotein CDCP1 in cancer--insights, opportunities, and challenges.
@ast
The cell surface glycoprotein CDCP1 in cancer--insights, opportunities, and challenges.
@en
The cell surface glycoprotein CDCP1 in cancer--insights, opportunities, and challenges.
@nl
P2093
P356
P1433
P1476
The cell surface glycoprotein CDCP1 in cancer--insights, opportunities, and challenges.
@en
P2093
Andreas Wortmann
Elena I Deryugina
James P Quigley
John D Hooper
P2860
P304
P356
10.1002/IUB.198
P577
2009-07-01T00:00:00Z