Cdc45 (cell division cycle protein 45) guards the gate of the Eukaryote Replisome helicase stabilizing leading strand engagement.
about
The Eukaryotic Replisome Goes Under the MicroscopeStructural Mechanisms of Hexameric Helicase Loading, Assembly, and UnwindingArchaeal MCM Proteins as an Analog for the Eukaryotic Mcm2-7 Helicase to Reveal Essential Features of Structure and FunctionStructure of the eukaryotic replicative CMG helicase suggests a pumpjack motion for translocationThe architecture of a eukaryotic replisome.Cryo-EM structures of the eukaryotic replicative helicase bound to a translocation substrate.Replication stress: getting back on trackOpening the Strands of Replication Origins-Still an Open QuestionCdc45-induced loading of human RPA onto single-stranded DNA.Eukaryotic Replicative Helicase Subunit Interaction with DNA and Its Role in DNA Replication.Structural basis for DNA 5´-end resection by RecJ.Structure of human Cdc45 and implications for CMG helicase functionDNA Interactions Probed by Hydrogen-Deuterium Exchange (HDX) Fourier Transform Ion Cyclotron Resonance Mass Spectrometry Confirm External Binding Sites on the Minichromosomal Maintenance (MCM) Helicase.Structure of eukaryotic CMG helicase at a replication fork and implications to replisome architecture and origin initiation.Mcm10 regulates DNA replication elongation by stimulating the CMG replicative helicase.Cryo-EM of dynamic protein complexes in eukaryotic DNA replication.Mechanisms and regulation of DNA replication initiation in eukaryotes.Structural insights into Cdc45 function: was there a nuclease at the heart of the ancestral replisome?Two Archaeal RecJ Nucleases from Methanocaldococcus jannaschii Show Reverse Hydrolysis Polarity: Implication to Their Unique Function in Archaea.Action of CMG with strand-specific DNA blocks supports an internal unwinding mode for the eukaryotic replicative helicase.Cryo-EM structure of a licensed DNA replication origin.The ring-shaped hexameric helicases that function at DNA replication forks.The crystal structure of Pyrococcus furiosus RecJ implicates it as an ancestor of eukaryotic Cdc45.The Eukaryotic CMG Helicase at the Replication Fork: Emerging Architecture Reveals an Unexpected Mechanism.Architecture of the Saccharomyces cerevisiae Replisome.The Human Replicative Helicase, the CMG Complex, as a Target for Anti-cancer Therapy.Crystal Structure of Cdc45 Suggests a Conformational Switch that May Regulate DNA Replication
P2860
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P2860
Cdc45 (cell division cycle protein 45) guards the gate of the Eukaryote Replisome helicase stabilizing leading strand engagement.
description
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2015 թուականի Յունուարին հրատարակուած գիտական յօդուած
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2015 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
Cdc45 (cell division cycle pro ...... ing leading strand engagement.
@ast
Cdc45 (cell division cycle pro ...... ing leading strand engagement.
@en
type
label
Cdc45 (cell division cycle pro ...... ing leading strand engagement.
@ast
Cdc45 (cell division cycle pro ...... ing leading strand engagement.
@en
prefLabel
Cdc45 (cell division cycle pro ...... ing leading strand engagement.
@ast
Cdc45 (cell division cycle pro ...... ing leading strand engagement.
@en
P2093
P2860
P356
P1476
Cdc45 (cell division cycle pro ...... zing leading strand engagement
@en
P2093
Alessandro Costa
James M Berger
Jingdan Liang
Michael R Botchan
Tatjana Petojevic
Zhijun Wang
P2860
P304
P356
10.1073/PNAS.1422003112
P407
P577
2015-01-05T00:00:00Z