Ketones and lactate increase cancer cell "stemness," driving recurrence, metastasis and poor clinical outcome in breast cancer: achieving personalized medicine via Metabolo-Genomics - Wikidata - wikimedia - TriplyDB

Ketones and lactate increase cancer cell "stemness," driving recurrence, metastasis and poor clinical outcome in breast cancer: achieving personalized medicine via Metabolo-Genomics

Ketones and lactate increase cancer cell "stemness," driving recurrence, metastasis and poor clinical outcome in breast cancer: achieving personalized medicine via Metabolo-Genomics

http://www.wikidata.org/entity/Q35051171

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Evolving Insights on Metabolism, Autophagy, and Epigenetics in Liver Myofibroblasts Cancer stem cell metabolism The Warburg effect and drug resistance Breast Cancer Metabolism and Mitochondrial Activity: The Possibility of Chemoprevention with Metformin Cancer metabolic reprogramming: importance, main features, and potentials for precise targeted anti-cancer therapies Autophagy in stem cells.Oncogenes induce the cancer-associated fibroblast phenotype: metabolic symbiosis and "fibroblast addiction" are new therapeutic targets for drug discovery Understanding the Warburg effect and the prognostic value of stromal caveolin-1 as a marker of a lethal tumor microenvironment Application of metabolomics in drug resistant breast cancer research Alternative fuels for cancer cells O-GlcNAcylation and Metabolic Reprograming in Cancer Commonly used methods of complementary medicine in the treatment of breast cancer Caveolin-1 in the regulation of cell metabolism: a cancer perspective Endothelial Progenitor Cells Physiology and Metabolic Plasticity in Brain Angiogenesis and Blood-Brain Barrier Modeling Reexamining cancer metabolism: Lactate production for carcinogenesis could be the purpose and explanation of the Warburg effect Broad Anti-tumor Activity of a Small Molecule that Selectively Targets the Warburg Effect and Lipogenesis Pretreatment elevated serum lactate dehydrogenase as a significant prognostic factor in malignant mesothelioma: A meta-analysis Xenohormetic and anti-aging activity of secoiridoid polyphenols present in extra virgin olive oil: a new family of gerosuppressant agents Ethanol exposure induces the cancer-associated fibroblast phenotype and lethal tumor metabolism: implications for breast cancer prevention Droplet Microfluidic Platform for the Determination of Single-Cell Lactate Release.Multi-omic data analysis using Galaxy.Quantitative measurement of organic acids in tissues from gastric cancer patients indicates increased glucose metabolism in gastric cancer.Investigation of discriminant metabolites in tamoxifen-resistant and choline kinase-alpha-downregulated breast cancer cells using 1H-nuclear magnetic resonance spectroscopy.Metformin against cancer stem cells through the modulation of energy metabolism: special considerations on ovarian cancer.Cancer cells metabolically "fertilize" the tumor microenvironment with hydrogen peroxide, driving the Warburg effect: implications for PET imaging of human tumors Pyruvate kinase expression (PKM1 and PKM2) in cancer-associated fibroblasts drives stromal nutrient production and tumor growth.Ketone body utilization drives tumor growth and metastasis.Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR cascade inhibitors: how mutations can result in therapy resistance and how to overcome resistance.Ketogenic diets: from cancer to mitochondrial diseases and beyond.Ovarian tumor-initiating cells display a flexible metabolism The ketogenic diet and hyperbaric oxygen therapy prolong survival in mice with systemic metastatic cancer.Mitochondria as new therapeutic targets for eradicating cancer stem cells: Quantitative proteomics and functional validation via MCT1/2 inhibition.Metabolic characterization of triple negative breast cancer.Evidence for a stromal-epithelial "lactate shuttle" in human tumors: MCT4 is a marker of oxidative stress in cancer-associated fibroblasts.Hydrogen peroxide fuels aging, inflammation, cancer metabolism and metastasis: the seed and soil also needs "fertilizer".Understanding the metabolic basis of drug resistance: therapeutic induction of the Warburg effect kills cancer cells.From inflammaging to healthy aging by dietary lifestyle choices: is epigenetics the key to personalized nutrition?Metabolic Signatures of Human Breast Cancer.Hyperactivation of oxidative mitochondrial metabolism in epithelial cancer cells in situ: visualizing the therapeutic effects of metformin in tumor tissue.Mitochondrial oxidative stress in cancer-associated fibroblasts drives lactate production, promoting breast cancer tumor growth: understanding the aging and cancer connection

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Ketones and lactate increase cancer cell "stemness," driving recurrence, metastasis and poor clinical outcome in breast cancer: achieving personalized medicine via Metabolo-Genomics

http://www.wikidata.org/entity/Q35051171

description

2011 nî lūn-bûn

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2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2011 թվականի ապրիլին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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Ketones and lactate increase c ...... medicine via Metabolo-Genomics

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Ketones and lactate increase c ...... medicine via Metabolo-Genomics

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Ketones and lactate increase c ...... medicine via Metabolo-Genomics

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Ketones and lactate increase c ...... medicine via Metabolo-Genomics

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Ketones and lactate increase c ...... medicine via Metabolo-Genomics

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Ketones and lactate increase c ...... medicine via Metabolo-Genomics

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Ketones and lactate increase c ...... medicine via Metabolo-Genomics

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Adam Ertel

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Chengwang Wang

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Erik S Knudsen

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Zhao Lin

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Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles.

Transcriptional evidence for the "Reverse Warburg Effect" in human breast cancer tumor stroma and metastasis: similarities with oxidative stress, inflammation, Alzheimer's disease, and "Neuron-Glia Metabolic Coupling"

Autophagy in cancer associated fibroblasts promotes tumor cell survival: Role of hypoxia, HIF1 induction and NFκB activation in the tumor stromal microenvironment

Ketones and lactate "fuel" tumor growth and metastasis: Evidence that epithelial cancer cells use oxidative mitochondrial metabolism

The autophagic tumor stroma model of cancer: Role of oxidative stress and ketone production in fueling tumor cell metabolism

Oxidative stress in cancer associated fibroblasts drives tumor-stroma co-evolution: A new paradigm for understanding tumor metabolism, the field effect and genomic instability in cancer cells

Understanding the "lethal" drivers of tumor-stroma co-evolution: emerging role(s) for hypoxia, oxidative stress and autophagy/mitophagy in the tumor micro-environment

The level of TACI gene expression in myeloma cells is associated with a signature of microenvironment dependence versus a plasmablastic signature

NCBI GEO: mining tens of millions of expression profiles--database and tools update

ArrayExpress--a public repository for microarray gene expression data at the EBI

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Aristotelis Tsirigos

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