Analysis of the transcriptional program induced by Raf in epithelial cells
about
PI-3 kinase activity is necessary for ERK1/2-induced disruption of mammary epithelial architecture.DACH1 is a cell fate determination factor that inhibits cyclin D1 and breast tumor growthIdentification and functional characterization of FMN2, a regulator of the cyclin-dependent kinase inhibitor p21The evolutionarily conserved EBR module of RALT/MIG6 mediates suppression of the EGFR catalytic activityNegative regulation of mitochondrial VDAC channels by C-Raf kinase.Molecularly targeted therapy for advanced hepatocellular carcinoma - a drug development crisis?Similar but different: distinct roles for KRAS and BRAF oncogenes in colorectal cancer development and therapy resistanceSteering tumor progression through the transcriptional response to growth factors and stromaLoss of transgelin in breast and colon tumors and in RIE-1 cells by Ras deregulation of gene expression through Raf-independent pathwaysRaf kinases in cancer-roles and therapeutic opportunitiesRAS oncogenes: weaving a tumorigenic webFrom bench to bedside: lessons learned in translating preclinical studies in cancer drug developmentTransforming growth factor-alpha prevents detachment-induced inhibition of c-Src kinase activity, Bcl-XL down-regulation, and apoptosis of intestinal epithelial cellsAn active form of Vav1 induces migration of mammary epithelial cells by stimulating secretion of an epidermal growth factor receptor ligandTranscript profiling of functionally related groups of genes during conditional differentiation of a mammalian cochlear hair cell line.Dachshund inhibits oncogene-induced breast cancer cellular migration and invasion through suppression of interleukin-8.RSK is a principal effector of the RAS-ERK pathway for eliciting a coordinate promotile/invasive gene program and phenotype in epithelial cells.Overexpression of Raf-1 and ERK1/2 in sacral chordoma and association with tumor recurrence.Survival signaling by C-RAF: mitochondrial reactive oxygen species and Ca2+ are critical targetsTDAG51 is an ERK signaling target that opposes ERK-mediated HME16C mammary epithelial cell transformation.The Dachshund gene in development and hormone-responsive tumorigenesis.G1/S cell cycle arrest provides anoikis resistance through Erk-mediated Bim suppression.Making cellular memories.RAS Interaction with PI3K: More Than Just Another Effector PathwayOpposing roles of the extracellular signal-regulated kinase and p38 mitogen-activated protein kinase cascades in Ras-mediated downregulation of tropomyosin.Reactive oxygen species via redox signaling to PI3K/AKT pathway contribute to the malignant growth of 4-hydroxy estradiol-transformed mammary epithelial cellsErbB2 receptor over-expression improves post-traumatic peripheral nerve regeneration in adult miceAnalysis of Ras-induced overproliferation in Drosophila hemocytes.p53 induction and activation of DDR1 kinase counteract p53-mediated apoptosis and influence p53 regulation through a positive feedback loop.The Ras/Raf/MEK/extracellular signal-regulated kinase pathway induces autocrine-paracrine growth inhibition via the leukemia inhibitory factor/JAK/STAT pathway.RAF and antioxidants prevent cell death induction after growth factor abrogation through regulation of Bcl-2 proteins.Genetic alterations of multiple tumor suppressors and oncogenes in the carcinogenesis and progression of lung cancer.Adhesion-mediated squamous cell carcinoma survival through ligand-independent activation of epidermal growth factor receptor.Prediction and measurement of an autoregulatory genetic moduleTumor necrosis factor-alpha stimulates the epithelial-to-mesenchymal transition of human colonic organoids.The transcriptional response to Raf activation is almost completely dependent on Mitogen-activated Protein Kinase Kinase activity and shows a major autocrine component.CX3CL1 promotes breast cancer via transactivation of the EGF pathwayCooperation of the ErbB2 receptor and transforming growth factor beta in induction of migration and invasion in mammary epithelial cells.Fibroblast growth factor 2-mediated translational control of IAPs blocks mitochondrial release of Smac/DIABLO and apoptosis in small cell lung cancer cellsTransforming growth factor-beta signaling during epithelial-mesenchymal transformation: implications for embryogenesis and tumor metastasis.
P2860
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P2860
Analysis of the transcriptional program induced by Raf in epithelial cells
description
2001 nî lūn-bûn
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2001 թուականի Ապրիլին հրատարակուած գիտական յօդուած
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2001 թվականի ապրիլին հրատարակված գիտական հոդված
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2001年の論文
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2001年学术文章
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2001年学术文章
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2001年学术文章
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2001年学术文章
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2001年学术文章
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2001年學術文章
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name
Analysis of the transcriptional program induced by Raf in epithelial cells
@ast
Analysis of the transcriptional program induced by Raf in epithelial cells
@en
type
label
Analysis of the transcriptional program induced by Raf in epithelial cells
@ast
Analysis of the transcriptional program induced by Raf in epithelial cells
@en
prefLabel
Analysis of the transcriptional program induced by Raf in epithelial cells
@ast
Analysis of the transcriptional program induced by Raf in epithelial cells
@en
P2093
P2860
P356
P1433
P1476
Analysis of the transcriptional program induced by Raf in epithelial cells
@en
P2093
H B Jefferies
P2860
P304
P356
10.1101/GAD.191101
P577
2001-04-01T00:00:00Z