Open-label, exploratory phase II trial of oral itraconazole for the treatment of basal cell carcinoma.
about
Cytotoxic and targeted therapy for hereditary cancersBasal Cell Carcinoma: A Comprehensive Review of Existing and Emerging Nonsurgical TherapiesTrial watch - inhibiting PARP enzymes for anticancer therapyAdvanced basal cell carcinoma, the hedgehog pathway, and treatment options - role of smoothened inhibitorsClinical Implications of Hedgehog Pathway Signaling in Prostate CancerThe Role of Hedgehog Signaling in Tumor Induced Bone DiseaseContext-dependent signal integration by the GLI code: the oncogenic load, pathways, modifiers and implications for cancer therapySonidegib, a novel smoothened inhibitor for the treatment of advanced basal cell carcinomaIonizing Radiation Exposure and Basal Cell Carcinoma PathogenesisItraconazole exerts its anti-melanoma effect by suppressing Hedgehog, Wnt, and PI3K/mTOR signaling pathwaysRecent advances in drug repositioning for the discovery of new anticancer drugsRepurposing Drugs in Oncology (ReDO)-mebendazole as an anti-cancer agentCUSP9* treatment protocol for recurrent glioblastoma: aprepitant, artesunate, auranofin, captopril, celecoxib, disulfiram, itraconazole, ritonavir, sertraline augmenting continuous low dose temozolomide.Repurposing Drugs in Oncology (ReDO)-itraconazole as an anti-cancer agent.Basal cell carcinoma-treatments for the commonest skin cancer.Itraconazole inhibits enterovirus replication by targeting the oxysterol-binding proteinMRT-92 inhibits Hedgehog signaling by blocking overlapping binding sites in the transmembrane domain of the Smoothened receptor.Inhibition of angiogenesis by selective estrogen receptor modulators through blockade of cholesterol trafficking rather than estrogen receptor antagonismSynthetic Small Molecule Inhibitors of Hh Signaling As Anti-Cancer Chemotherapeutics.Updates on Psoriasis and Cutaneous Oncology: Proceedings from the 2015 MauiDerm MeetingTargeting Notch, Hedgehog, and Wnt pathways in cancer stem cells: clinical updateTherapeutic Effects of Repurposed Therapies in Non-Small Cell Lung Cancer: What Is Old Is New Again.Identification of Novel Smoothened Ligands Using Structure-Based Docking.Antifungal drug itraconazole targets VDAC1 to modulate the AMPK/mTOR signaling axis in endothelial cells.Shh and p50/Bcl3 signaling crosstalk drives pathogenesis of BCCs in Gorlin syndrome.Effects of Combined Treatment With Arsenic Trioxide and Itraconazole in Patients With Refractory Metastatic Basal Cell Carcinoma.Posaconazole, a Second-Generation Triazole Antifungal Drug, Inhibits the Hedgehog Signaling Pathway and Progression of Basal Cell Carcinoma.Itraconazole induces apoptosis and cell cycle arrest via inhibiting Hedgehog signaling in gastric cancer cells.Emerging drugs and combination strategies for basal cell carcinoma.Recent advances in the design of Hedgehog pathway inhibitors for the treatment of malignancies.Optimal management of skin cancer in immunosuppressed patients.Efficacy and safety of vismodegib : a new therapeutic agent in the treatment of basal cell carcinoma.Sonic hedgehog signaling in Basal cell nevus syndrome.Novel targets for the treatment of ameloblastoma.Regulation of the oncoprotein Smoothened by small molecules.Pharmacologic treatment options for advanced epithelial skin cancer.Repurposing itraconazole as an anticancer agent.Non-melanoma skin cancer: new and future synthetic drug treatments.Basal cell carcinoma pathogenesis and therapy involving hedgehog signaling and beyond.GLI3 repressor determines Hedgehog pathway activation and is required for response to SMO antagonist glasdegib in AML.
P2860
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P2860
Open-label, exploratory phase II trial of oral itraconazole for the treatment of basal cell carcinoma.
description
2014 nî lūn-bûn
@nan
2014 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Open-label, exploratory phase ...... tment of basal cell carcinoma.
@ast
Open-label, exploratory phase ...... tment of basal cell carcinoma.
@en
type
label
Open-label, exploratory phase ...... tment of basal cell carcinoma.
@ast
Open-label, exploratory phase ...... tment of basal cell carcinoma.
@en
prefLabel
Open-label, exploratory phase ...... tment of basal cell carcinoma.
@ast
Open-label, exploratory phase ...... tment of basal cell carcinoma.
@en
P2093
P356
P1476
Open-label, exploratory phase ...... tment of basal cell carcinoma.
@en
P2093
Anita Gilliam
Daniel J Kim
Javier Montoya
Jean Y Tang
Kalyani Chandra
Katrina Spaunhurst
Monserrat Molgo
Philip A Beachy
Rita Khodosh
P304
P356
10.1200/JCO.2013.49.9525
P407
P577
2014-02-03T00:00:00Z