Region-specific dissociation of neuronal loss and neurofibrillary pathology in a mouse model of tauopathy.
about
The Metamorphic Nature of the Tau Protein: Dynamic Flexibility Comes at a CostTau Oligomers: The Toxic Player at Synapses in Alzheimer's DiseaseMouse models of frontotemporal dementiaMechanisms of protein seeding in neurodegenerative diseasesTherapeutic and diagnostic challenges for frontotemporal dementiaTangles, Toxicity, and Tau Secretion in AD - New Approaches to a Vexing ProblemThe role of tau in neurodegenerative diseases and its potential as a therapeutic targetRescue from tau-induced neuronal dysfunction produces insoluble tau oligomersTau overexpression impacts a neuroinflammation gene expression network perturbed in Alzheimer's diseaseSystems biology of neurodegenerative diseasesTau accumulation causes mitochondrial distribution deficits in neurons in a mouse model of tauopathy and in human Alzheimer's disease brainGenotype-specific differences between mouse CNS stem cell lines expressing frontotemporal dementia mutant or wild type human tauZebrafish models of TauopathyNasal neuron PET imaging quantifies neuron generation and degenerationTau pathology induces loss of GABAergic interneurons leading to altered synaptic plasticity and behavioral impairments.Ketogenic diet improves motor performance but not cognition in two mouse models of Alzheimer's pathologyChanges in dendritic complexity and spine morphology in transgenic mice expressing human wild-type tau.Early axonopathy preceding neurofibrillary tangles in mutant tau transgenic mice.Hyperphosphorylated tau in parahippocampal cortex impairs place learning in aged mice expressing wild-type human tauFTDP-17 mutations in Tau alter the regulation of microtubule dynamics: an "alternative core" model for normal and pathological Tau action.Aggregation of detergent-insoluble tau is involved in neuronal loss but not in synaptic lossElectrophysiological changes precede morphological changes to frontal cortical pyramidal neurons in the rTg4510 mouse model of progressive tauopathyNeurofibrillary tangle-bearing neurons are functionally integrated in cortical circuits in vivo.Tau deposition drives neuropathological, inflammatory and behavioral abnormalities independently of neuronal loss in a novel mouse modelCo-expression of truncated and full-length tau induces severe neurotoxicityTangle-bearing neurons survive despite disruption of membrane integrity in a mouse model of tauopathyPericellular innervation of neurons expressing abnormally hyperphosphorylated tau in the hippocampal formation of Alzheimer's disease patients.Differential effect of three-repeat and four-repeat tau on mitochondrial axonal transport.Identification of oligomers at early stages of tau aggregation in Alzheimer's disease.TOC1: a valuable tool in assessing disease progression in the rTg4510 mouse model of tauopathy.Stem cell models of Alzheimer's disease: progress and challenges.Structural and functional changes in tau mutant mice neurons are not linked to the presence of NFTs.RanBP9 overexpression accelerates loss of dendritic spines in a mouse model of Alzheimer's diseasePrediction of miRNA-mRNA associations in Alzheimer's disease mice using network topology.Identification of Stk25 as a genetic modifier of Tau phosphorylation in Dab1-mutant mice.LPS- induced inflammation exacerbates phospho-tau pathology in rTg4510 miceProbing the biology of Alzheimer's disease in mice.Protein tau: prime cause of synaptic and neuronal degeneration in Alzheimer's disease.Focal expression of mutated tau in entorhinal cortex neurons of rats impairs spatial working memory.Tau pathology does not affect experience-driven single-neuron and network-wide Arc/Arg3.1 responses.
P2860
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P2860
Region-specific dissociation of neuronal loss and neurofibrillary pathology in a mouse model of tauopathy.
description
2006 nî lūn-bûn
@nan
2006 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Region-specific dissociation o ...... in a mouse model of tauopathy.
@ast
Region-specific dissociation o ...... in a mouse model of tauopathy.
@en
type
label
Region-specific dissociation o ...... in a mouse model of tauopathy.
@ast
Region-specific dissociation o ...... in a mouse model of tauopathy.
@en
prefLabel
Region-specific dissociation o ...... in a mouse model of tauopathy.
@ast
Region-specific dissociation o ...... in a mouse model of tauopathy.
@en
P2093
P2860
P1476
Region-specific dissociation o ...... in a mouse model of tauopathy.
@en
P2093
George A Carlson
Jennifer D Orne
Karen H Ashe
Karen SantaCruz
Rose Pitstick
P2860
P304
P356
10.2353/AJPATH.2006.050840
P407
P577
2006-05-01T00:00:00Z