Expression of C-terminal deleted p53 isoforms in neuroblastoma. - Wikidata - wikimedia - TriplyDB

Expression of C-terminal deleted p53 isoforms in neuroblastoma.

Expression of C-terminal deleted p53 isoforms in neuroblastoma.

http://www.wikidata.org/entity/Q35130560

about

CDK Inhibitors Roscovitine and CR8 Trigger Mcl-1 Down-Regulation and Apoptotic Cell Death in Neuroblastoma Cells Chd5 requires PHD-mediated histone 3 binding for tumor suppression Antagomir-17-5p abolishes the growth of therapy-resistant neuroblastoma through p21 and BIM RUNX3 modulates DNA damage-mediated phosphorylation of tumor suppressor p53 at Ser-15 and acts as a co-activator for p53.Combination of N-(4-hydroxyphenyl) retinamide and genistein increased apoptosis in neuroblastoma SK-N-BE2 and SH-SY5Y xenografts p53 basic C terminus regulates p53 functions through DNA binding modulation of subset of target genes Complex molecular mechanisms cooperate to mediate histone deacetylase inhibitors anti-tumour activity in neuroblastoma cells.p53 and its isoforms in cancer p53 and little brother p53/47: linking IRES activities with protein functions.The GSK461364 PLK1 inhibitor exhibits strong antitumoral activity in preclinical neuroblastoma models.Peroxisome proliferator-activated receptor-β/δ inhibits human neuroblastoma cell tumorigenesis by inducing p53- and SOX2-mediated cell differentiation.Expression of p53β and Δ133p53 isoforms in different gastric tissues.Identification of flubendazole as potential anti-neuroblastoma compound in a large cell line screen.A rapid screening system evaluates novel inhibitors of DNA methylation and suggests F-box proteins as potential therapeutic targets for high-risk neuroblastoma.Structurally diverse MDM2-p53 antagonists act as modulators of MDR-1 function in neuroblastoma.Hsp90 inhibition increases p53 expression and destabilizes MYCN and MYC in neuroblastoma.S(+)-ibuprofen destabilizes MYC/MYCN and AKT, increases p53 expression, and induces unfolded protein response and favorable phenotype in neuroblastoma cell lines.Differential effects of diverse p53 isoforms on TAp73 transcriptional activity and apoptosis.Downregulation of splicing factor SRSF3 induces p53β, an alternatively spliced isoform of p53 that promotes cellular senescence.The p53 isoforms are differentially modified by Mdm2.SU5416 and EGCG work synergistically and inhibit angiogenic and survival factors and induce cell cycle arrest to promote apoptosis in human malignant neuroblastoma SH-SY5Y and SK-N-BE2 cells.Checkpoint kinase inhibitor synergizes with DNA-damaging agents in G1 checkpoint-defective neuroblastoma.Effect of bortezomib on human neuroblastoma: analysis of molecular mechanisms involved in cytotoxicity.Smac mimetic LCL161 supports neuroblastoma chemotherapy in a drug class-dependent manner and synergistically interacts with ALK inhibitor TAE684 in cells with ALK mutation F1174L.Testing of SNS-032 in a Panel of Human Neuroblastoma Cell Lines with Acquired Resistance to a Broad Range of Drugs.Role of Δ133p53 isoform in NF-κB inhibitor PDTC-mediated growth inhibition of MKN45 gastric cancer cells p53, SKP2, and DKK3 as MYCN Target Genes and Their Potential Therapeutic Significance.Identification of nonsense-mediated mRNA decay pathway as a critical regulator of p53 isoform β.Lysine-specific demethylase LSD1 regulates autophagy in neuroblastoma through SESN2-dependent pathway.Combined epigenetic and differentiation-based treatment inhibits neuroblastoma tumor growth and links HIF2α to tumor suppression.

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P2860

Expression of C-terminal deleted p53 isoforms in neuroblastoma.

http://www.wikidata.org/entity/Q35130560

description

2006 nî lūn-bûn

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2006 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

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2006 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年论文

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name

Expression of C-terminal deleted p53 isoforms in neuroblastoma.

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Expression of C-terminal deleted p53 isoforms in neuroblastoma.

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type

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Expression of C-terminal deleted p53 isoforms in neuroblastoma.

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Expression of C-terminal deleted p53 isoforms in neuroblastoma.

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prefLabel

Expression of C-terminal deleted p53 isoforms in neuroblastoma.

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Expression of C-terminal deleted p53 isoforms in neuroblastoma.

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Nucleic Acids Research

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Expression of C-terminal deleted p53 isoforms in neuroblastoma.

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David Goldschneider

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Emilie Horvilleur

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Evelyne May

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Evelyne Wittmer-Dupret

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Gisèle Danglot

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Hughes de Thé

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Jean Bénard

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Karine Million

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Louis-François Plassa

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P2860

p53 isoforms can regulate p53 transcriptional activity.

The C terminus of p53 family proteins is a cell fate determinant

Therapeutic activity of CPT-11, a DNA-topoisomerase I inhibitor, against peripheral primitive neuroectodermal tumour and neuroblastoma xenografts

Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers

Reassessment of the TP53 mutation database in human disease by data mining with a library of TP53 missense mutations.

p53 and human cancer: the first ten thousand mutations.

Twenty years of p53 research: structural and functional aspects of the p53 protein.

Oncogenic mutations of the p53 tumor suppressor: the demons of the guardian of the genome.

Parc: a cytoplasmic anchor for p53.

Wild-type p53 protein undergoes cytoplasmic sequestration in undifferentiated neuroblastomas but not in differentiated tumors

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19

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34

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