Enhancer control of V(D)J recombination at the TCRbeta locus: differential effects on DNA cleavage and joining.
about
RORgammaT, a thymus-specific isoform of the orphan nuclear receptor RORgamma / TOR, is up-regulated by signaling through the pre-T cell receptor and binds to the TEA promoterIn vivo reinsertion of excised episomes by the V(D)J recombinase: a potential threat to genomic stability.Genomic organization and recombinational unit duplication-driven evolution of ovine and bovine T cell receptor gamma loci.Analysis of variable (diversity) joining recombination in DNAdependent protein kinase (DNA-PK)-deficient mice reveals DNA-PK-independent pathways for both signal and coding joint formation.Definition of a T-cell receptor beta gene core enhancer of V(D)J recombination by transgenic mapping.Characterization of human αβTCR repertoire and discovery of D-D fusion in TCRβ chains.Regulation of V(D)J recombination: a dominant role for promoter positioning in gene segment accessibility.Activation of p38 MAP kinase by DNA double-strand breaks in V(D)J recombination induces a G2/M cell cycle checkpoint.Gene segment selection in V(D)J recombination: accessibility and beyond.The interleukin 7 receptor is required for T cell receptor gamma locus accessibility to the V(D)J recombinase.Chromatin remodeling by the T cell receptor (TCR)-beta gene enhancer during early T cell development: Implications for the control of TCR-beta locus recombination.Restrictions limiting the generation of DNA double strand breaks during chromosomal V(D)J recombination.RAG2's non-core domain contributes to the ordered regulation of V(D)J recombination.The T cell receptor beta enhancer promotes access and pairing of Dbeta and Jbeta gene segments during V(D)J recombinationLeaky severe combined immunodeficiency and aberrant DNA rearrangements due to a hypomorphic RAG1 mutation.V(D)J recombination: Born to be wildRegulation of V(D)J recombination by transcriptional promoters.TCRalpha enhancer activation occurs via a conformational change of a pre-assembled nucleo-protein complex.Reassignment of the murine 3'TRDD1 recombination signal sequence.
P2860
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P2860
Enhancer control of V(D)J recombination at the TCRbeta locus: differential effects on DNA cleavage and joining.
description
1998 nî lūn-bûn
@nan
1998 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Enhancer control of V(D)J reco ...... s on DNA cleavage and joining.
@ast
Enhancer control of V(D)J reco ...... s on DNA cleavage and joining.
@en
type
label
Enhancer control of V(D)J reco ...... s on DNA cleavage and joining.
@ast
Enhancer control of V(D)J reco ...... s on DNA cleavage and joining.
@en
prefLabel
Enhancer control of V(D)J reco ...... s on DNA cleavage and joining.
@ast
Enhancer control of V(D)J reco ...... s on DNA cleavage and joining.
@en
P2093
P2860
P356
P1433
P1476
Enhancer control of V(D)J reco ...... s on DNA cleavage and joining.
@en
P2093
M S Schlissel
P Stanhope-Baker
W M Hempel
P2860
P304
P356
10.1101/GAD.12.15.2305
P577
1998-08-01T00:00:00Z