Structure and function in rhodopsin: replacement by alanine of cysteine residues 110 and 187, components of a conserved disulfide bond in rhodopsin, affects the light-activated metarhodopsin II state.
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Crystal Structure of a Thermally Stable Rhodopsin MutantUnderstanding functional residues of the cannabinoid CB1.Cysteine residues in the large extracellular loop (EC2) are essential for the function of the stress-regulated glycoprotein M6aThe molecular basis for the high photosensitivity of rhodopsinBinding mode prediction of conformationally restricted anandamide analogs within the CB1 receptor.Projection structure of frog rhodopsin in two crystal forms.Identification of orthosteric and allosteric site mutations in M2 muscarinic acetylcholine receptors that contribute to ligand-selective signaling biasStructure and function in rhodopsin: expression of functional mammalian opsin in Saccharomyces cerevisiaeHomology model of the CB1 cannabinoid receptor: sites critical for nonclassical cannabinoid agonist interaction.Highly conserved tyrosine stabilizes the active state of rhodopsin.In vivo assembly of rhodopsin from expressed polypeptide fragmentsG protein-coupled receptor rhodopsin: a prospectus.Structure and function in rhodopsin: the fate of opsin formed upon the decay of light-activated metarhodopsin II in vitro.G protein-coupled receptor rhodopsin.Molecular Architecture of G Protein-Coupled Receptors.Structure and function in rhodopsin: the role of asparagine-linked glycosylation.Retinal counterion switch in the photoactivation of the G protein-coupled receptor rhodopsinThe extracellular loop 2 (ECL2) of the human histamine H4 receptor substantially contributes to ligand binding and constitutive activity.Structure and function in rhodopsin: packing of the helices in the transmembrane domain and folding to a tertiary structure in the intradiscal domain are coupledStructure and function in rhodopsin: topology of the C-terminal polypeptide chain in relation to the cytoplasmic loopsThermal stability of rhodopsin and progression of retinitis pigmentosa: comparison of S186W and D190N rhodopsin mutants.Structure and function in rhodopsin: further elucidation of the role of the intradiscal cysteines, Cys-110, -185, and -187, in rhodopsin folding and function.Helix movement is coupled to displacement of the second extracellular loop in rhodopsin activation.Structure and function in rhodopsin: high level expression of a synthetic bovine opsin gene and its mutants in stable mammalian cell lines.Retinitis pigmentosa mutants provide insight into the role of the N-terminal cap in rhodopsin folding, structure, and function.Structure and function in rhodopsin: correct folding and misfolding in point mutants at and in proximity to the site of the retinitis pigmentosa mutation Leu-125-->Arg in the transmembrane helix C.Extracellular disulfide bonds support scavenger receptor class B type I-mediated cholesterol transport.Lifting the lid on GPCRs: the role of extracellular loops.The role of conserved extracellular cysteine residues in vasopressin V2 receptor function and properties of two naturally occurring mutant receptors with additional extracellular cysteine residues.Possible role of rare variants in Trace amine associated receptor 1 in schizophrenia.Structural insight into the role of the human melanocortin 3 receptor cysteine residues on receptor function.Structural insights into the role of the ACTH receptor cysteine residues on receptor function.Systematic analysis of the entire second extracellular loop of the V(1a) vasopressin receptor: key residues, conserved throughout a G-protein-coupled receptor family, identified.A disulfide bond between conserved cysteines in the extracellular loops of the human VIP receptor is required for binding and activation.Structural features of the central cannabinoid CB1 receptor involved in the binding of the specific CB1 antagonist SR 141716A.Probing the "message:address" sites for chemoattractant binding to the C5a receptor. Mutagenesis of hydrophilic and proline residues within the transmembrane segments.Roles of Met-34, Cys-64, and Arg-75 in the assembly of human connexin 26. Implication for key amino acid residues for channel formation and function.Salt effects on the conformational stability of the visual G-protein-coupled receptor rhodopsin.Dlx2 homeobox gene transcriptional regulation of Trkb neurotrophin receptor expression during mouse retinal development.Conserved residues in the extracellular loops of short-wavelength cone visual pigments.
P2860
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P2860
Structure and function in rhodopsin: replacement by alanine of cysteine residues 110 and 187, components of a conserved disulfide bond in rhodopsin, affects the light-activated metarhodopsin II state.
description
1994 nî lūn-bûn
@nan
1994 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
Structure and function in rhod ...... ivated metarhodopsin II state.
@ast
Structure and function in rhod ...... ivated metarhodopsin II state.
@en
type
label
Structure and function in rhod ...... ivated metarhodopsin II state.
@ast
Structure and function in rhod ...... ivated metarhodopsin II state.
@en
prefLabel
Structure and function in rhod ...... ivated metarhodopsin II state.
@ast
Structure and function in rhod ...... ivated metarhodopsin II state.
@en
P2093
P2860
P356
P1476
Structure and function in rhod ...... ivated metarhodopsin II state.
@en
P2093
F F Davidson
H G Khorana
P C Loewen
P2860
P304
P356
10.1073/PNAS.91.9.4029
P407
P577
1994-04-01T00:00:00Z