The carboxy-terminal fragment of inhibitor-2 of protein phosphatase-2A induces Alzheimer disease pathology and cognitive impairment.
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Protein phosphatase 2A dysfunction in Alzheimer's diseaseMechanism of inhibition of PP2A activity and abnormal hyperphosphorylation of tau by I2(PP2A)/SETTherapeutic benefits of a component of coffee in a rat model of Alzheimer's disease.Phosphoprotein phosphatase 2A: a novel druggable target for Alzheimer's diseaseProtein phosphatases and Alzheimer's diseaseMemantine Attenuates Alzheimer's Disease-Like Pathology and Cognitive ImpairmentSilencing PP2A inhibitor by lenti-shRNA interference ameliorates neuropathologies and memory deficits in tg2576 mice.Silencing [Formula: see text] Rescues Tau Pathologies and Memory Deficits through Rescuing PP2A and Inhibiting GSK-3β Signaling in Human Tau Transgenic Mice.Cytoplasmic SET induces tau hyperphosphorylation through a decrease of methylated phosphatase 2A.Cytoplasmic retention of protein phosphatase 2A inhibitor 2 (I2PP2A) induces Alzheimer-like abnormal hyperphosphorylation of Tau.CBP gene transfer increases BDNF levels and ameliorates learning and memory deficits in a mouse model of Alzheimer's disease.Asparagine endopeptidase is an innovative therapeutic target for neurodegenerative diseases.The N-terminal Set-β Protein Isoform Induces Neuronal DeathAPOE-mimetic peptides reduce behavioral deficits, plaques and tangles in Alzheimer's disease transgenicsActivation of asparaginyl endopeptidase leads to Tau hyperphosphorylation in Alzheimer disease.Asperterpenes A and B, two unprecedented meroterpenoids from Aspergillus terreus with BACE1 inhibitory activities.Glycogen synthase kinase-3 inhibitors: Rescuers of cognitive impairments.Microtubule-associated protein tau as a therapeutic target in Alzheimer's disease.Alzheimer disease therapeutics: focus on the disease and not just plaques and tanglesFurther understanding of tau phosphorylation: implications for therapy.Behind the curtain of tauopathy: a show of multiple players orchestrating tau toxicity.Tau-directed approaches for the treatment of Alzheimer's disease: focus on leuco-methylthioninium.Upregulation of SET expression by BACE1 and its implications in Down syndrome.Correcting the expression of miRNA-155 represses PP2Ac and enhances the release of IL-2 in PBMCs of juvenile SLE patients.An experimental rat model of sporadic Alzheimer's disease and rescue of cognitive impairment with a neurotrophic peptide.Alzheimer disease and amyotrophic lateral sclerosis: an etiopathogenic connectionHyperphosphorylation-induced tau oligomersSex Differences in the Cognitive and Hippocampal Effects of Streptozotocin in an Animal Model of Sporadic AD.Eicosanoyl-5-hydroxytryptamide (EHT) prevents Alzheimer's disease-related cognitive and electrophysiological impairments in mice exposed to elevated concentrations of oligomeric beta-amyloid.Upregulation of astrocytes protein phosphatase-2A stimulates astrocytes migration via inhibiting p38 MAPK in tg2576 mice.Activation of Cdk5/p25 and tau phosphorylation following chronic brain hypoperfusion in rats involves microRNA-195 down-regulation.Combination of PPT with LiCl Treatment Prevented Bilateral Ovariectomy-Induced Hippocampal-Dependent Cognition Deficit in Rats.Regulation of SET Gene Expression by NFkB.Tau-based therapeutics for Alzheimer's disease: active and passive immunotherapy.Trillium tschonoskii maxim extract attenuates abnormal Tau phosphorylation.Untangling Tau and Iron: Exploring the Interaction Between Iron and Tau in Neurodegeneration
P2860
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P2860
The carboxy-terminal fragment of inhibitor-2 of protein phosphatase-2A induces Alzheimer disease pathology and cognitive impairment.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
The carboxy-terminal fragment ...... logy and cognitive impairment.
@ast
The carboxy-terminal fragment ...... logy and cognitive impairment.
@en
type
label
The carboxy-terminal fragment ...... logy and cognitive impairment.
@ast
The carboxy-terminal fragment ...... logy and cognitive impairment.
@en
prefLabel
The carboxy-terminal fragment ...... logy and cognitive impairment.
@ast
The carboxy-terminal fragment ...... logy and cognitive impairment.
@en
P2093
P2860
P356
P1433
P1476
The carboxy-terminal fragment ...... logy and cognitive impairment.
@en
P2093
Aurelian Radu
Erik Kohlbrenner
Julie Blanchard
Khalid Iqbal
Nathalie Clement
R Michael Linden
Xiaochuan Wang
P2860
P304
P356
10.1096/FJ.10-158477
P407
P577
2010-07-22T00:00:00Z