Structural biology. Crystal structure of a CRISPR RNA-guided surveillance complex bound to a ssDNA target
about
Cpf1 is a single RNA-guided endonuclease of a class 2 CRISPR-Cas systemDiversity of CRISPR-Cas immune systems and molecular machinesBiogenesis pathways of RNA guides in archaeal and bacterial CRISPR-Cas adaptive immunityMechanism of CRISPR-RNA guided recognition of DNA targets in Escherichia coli.STRUCTURAL BIOLOGY. A Cas9-guide RNA complex preorganized for target DNA recognitionStructural basis for dimer formation of the CRISPR-associated protein Csm2 of Thermotoga maritimaStructural basis for promiscuous PAM recognition in type I-E Cascade from E. coliRNA targeting by the type III-A CRISPR-Cas Csm complex of Thermus thermophilusStructure Principles of CRISPR-Cas Surveillance and Effector ComplexesTarget DNA recognition and cleavage by a reconstituted Type I-G CRISPR-Cas immune effector complex.An updated evolutionary classification of CRISPR-Cas systems.The role of Cas8 in type I CRISPR interference.Multiple mechanisms for CRISPR-Cas inhibition by anti-CRISPR proteinsCRISPR-Cas immunity in prokaryotes.Target RNA capture and cleavage by the Cmr type III-B CRISPR-Cas effector complexRational design of a split-Cas9 enzyme complexThe CRISPR-associated DNA-cleaving enzyme Cpf1 also processes precursor CRISPR RNA.C2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector.Diverse evolutionary roots and mechanistic variations of the CRISPR-Cas systems.Essential structural and functional roles of the Cmr4 subunit in RNA cleavage by the Cmr CRISPR-Cas complex.Structural Principles of CRISPR RNA Processing.CRISPR RNA binding and DNA target recognition by purified Cascade complexes from Escherichia coliCmr4 is the slicer in the RNA-targeting Cmr CRISPR complexMechanism of foreign DNA recognition by a CRISPR RNA-guided surveillance complex from Pseudomonas aeruginosaThe structural biology of CRISPR-Cas systemsClustered Regularly Interspaced Short Palindromic Repeat-Dependent, Biofilm-Specific Death of Pseudomonas aeruginosa Mediated by Increased Expression of Phage-Related Genes.Three CRISPR-Cas immune effector complexes coexist in Pyrococcus furiosus.A Conserved Structural Chassis for Mounting Versatile CRISPR RNA-Guided Immune Responses.The Cas6e ribonuclease is not required for interference and adaptation by the E. coli type I-E CRISPR-Cas system.Cas3 is a limiting factor for CRISPR-Cas immunity in Escherichia coli cells lacking H-NS.Structural biology. Structures of the CRISPR-Cmr complex reveal mode of RNA target positioning.DNA targeting by the type I-G and type I-A CRISPR-Cas systems of Pyrococcus furiosus.CRISPR interference and priming varies with individual spacer sequencesThe CRISPR RNA-guided surveillance complex in Escherichia coli accommodates extended RNA spacersDNA Targeting by a Minimal CRISPR RNA-Guided Cascade.Altered stoichiometry Escherichia coli Cascade complexes with shortened CRISPR RNA spacers are capable of interference and primed adaptation.The Adaptive Immune System of Haloferax volcanii.DNA and RNA interference mechanisms by CRISPR-Cas surveillance complexes.Multiple nucleic acid cleavage modes in divergent type III CRISPR systems.Impact of Different Target Sequences on Type III CRISPR-Cas Immunity.
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Structural biology. Crystal structure of a CRISPR RNA-guided surveillance complex bound to a ssDNA target
description
2014 nî lūn-bûn
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2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
2014年论文
@zh
2014年论文
@zh-cn
name
Structural biology. Crystal st ...... omplex bound to a ssDNA target
@ast
Structural biology. Crystal st ...... omplex bound to a ssDNA target
@en
type
label
Structural biology. Crystal st ...... omplex bound to a ssDNA target
@ast
Structural biology. Crystal st ...... omplex bound to a ssDNA target
@en
prefLabel
Structural biology. Crystal st ...... omplex bound to a ssDNA target
@ast
Structural biology. Crystal st ...... omplex bound to a ssDNA target
@en
P2093
P2860
P356
P1433
P1476
Structural biology. Crystal st ...... omplex bound to a ssDNA target
@en
P2093
Annie Héroux
Sabin Mulepati
Scott Bailey
P2860
P304
P356
10.1126/SCIENCE.1256996
P407
P577
2014-08-14T00:00:00Z