Role of beta 1 and beta 2 integrins in the adhesion of human CD34hi stem cells to bone marrow stroma
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Bcr-Abl induces abnormal cytoskeleton remodeling, beta1 integrin clustering and increased cell adhesion to fibronectin through the Abl interactor 1 pathwayPharmacological inhibition of caspase and calpain proteases: a novel strategy to enhance the homing responses of cord blood HSPCs during expansionAssociation of the Cas-like molecule HEF1 with CrkL following integrin and antigen receptor signaling in human B-cells: potential relevance to neoplastic lymphohematopoietic cellsVLA-4-mediated interactions between normal human hematopoietic progenitors and stromal cellsSmall molecule agonist of very late antigen-4 (VLA-4) integrin induces progenitor cell adhesionBone marrow niche-mimetics modulate HSPC function via integrin signaling.CD44 and adhesion of normal and leukemic CD34+ cells to bone marrow stroma.The VLA4/VCAM-1 adhesion pathway defines contrasting mechanisms of lodgement of transplanted murine hemopoietic progenitors between bone marrow and spleenc-Myb and Ets proteins synergize to overcome transcriptional repression by ZEB.Mesenchymal stem cells as cellular vectors for pediatric neurological disordersbeta-Catenin expression in the bone marrow microenvironment is required for long-term maintenance of primitive hematopoietic cells.Neutrophils are indispensable for hematopoietic stem cell mobilization induced by interleukin-8 in miceThe synergy between stem cell factor (SCF) and granulocyte colony-stimulating factor (G-CSF): molecular basis and clinical relevance.Interferon-alpha restores normal adhesion of chronic myelogenous leukemia hematopoietic progenitors to bone marrow stroma by correcting impaired beta 1 integrin receptor function.VLA-4-dependent myeloma cell adhesion.Macrophage-colony-stimulating factor regulates expression of the integrins alpha 4 beta 1 and alpha 5 beta 1 by murine bone marrow macrophages.Serpina1 is a potent inhibitor of IL-8-induced hematopoietic stem cell mobilization.The CXCR4 and adhesion molecule expression of CD34+ hematopoietic cells mobilized by "on-demand" addition of plerixafor to granulocyte-colony-stimulating factor.Expression of Pitx2 in stromal cells is required for normal hematopoiesisTargeting stem cell niches and trafficking for cardiovascular therapyFunctional and structural insights into ASB2alpha, a novel regulator of integrin-dependent adhesion of hematopoietic cellsPrevention of interleukin-8-induced mobilization of hematopoietic progenitor cells in rhesus monkeys by inhibitory antibodies against the metalloproteinase gelatinase B (MMP-9).Regulation of lymphoid and myeloid leukemic cell survival: role of stromal cell adhesion molecules.Direct adhesion to bone marrow stroma via fibronectin receptors inhibits hematopoietic progenitor proliferationTreatment of marrow stroma with interferon-alpha restores normal beta 1 integrin-dependent adhesion of chronic myelogenous leukemia hematopoietic progenitors. Role of MIP-1 alpha.Hematopoietic stem cells: transcriptional regulation, ex vivo expansion and clinical application.Dysregulated in vitro hematopoiesis, radiosensitivity, proliferation, and osteoblastogenesis with marrow from SAMP6 mice.miR-17 promotes expansion and adhesion of human cord blood CD34(+) cells in vitro.The role of novel and known extracellular matrix and adhesion molecules in the homeostatic and regenerative bone marrow microenvironmentInvolvement of proteases in cytokine-induced hematopoietic stem cell mobilization.Mutation of putative divalent cation sites in the alpha 4 subunit of the integrin VLA-4: distinct effects on adhesion to CS1/fibronectin, VCAM-1, and invasin.Interchangeable alpha chain cytoplasmic domains play a positive role in control of cell adhesion mediated by VLA-4, a beta 1 integrin.Cytokines increase human hemopoietic cell adhesiveness by activation of very late antigen (VLA)-4 and VLA-5 integrins.Downregulation of tenascin expression by glucocorticoids in bone marrow stromal cells and in fibroblasts.Local signals in stem cell-based bone marrow regeneration.Peripheralization of hemopoietic progenitors in primates treated with anti-VLA4 integrin.Signaling pathways in self-renewing hematopoietic and leukemic stem cells: do all stem cells need a niche?Surface-immobilization of adhesion peptides on substrate for ex vivo expansion of cryopreserved umbilical cord blood CD34+ cellsCrosstalk between CXCR4/stromal derived factor-1 and VLA-4/VCAM-1 pathways regulates neutrophil retention in the bone marrow.Targeting the leukemic stem cell: the Holy Grail of leukemia therapy
P2860
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P2860
Role of beta 1 and beta 2 integrins in the adhesion of human CD34hi stem cells to bone marrow stroma
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
1992年论文
@zh
1992年论文
@zh-cn
name
Role of beta 1 and beta 2 inte ...... em cells to bone marrow stroma
@ast
Role of beta 1 and beta 2 inte ...... em cells to bone marrow stroma
@en
type
label
Role of beta 1 and beta 2 inte ...... em cells to bone marrow stroma
@ast
Role of beta 1 and beta 2 inte ...... em cells to bone marrow stroma
@en
prefLabel
Role of beta 1 and beta 2 inte ...... em cells to bone marrow stroma
@ast
Role of beta 1 and beta 2 inte ...... em cells to bone marrow stroma
@en
P2093
P2860
P356
P1476
Role of beta 1 and beta 2 inte ...... em cells to bone marrow stroma
@en
P2093
J S Greenberger
M E Hemler
P Anklesaria
P2860
P304
P356
10.1172/JCI115870
P407
P577
1992-08-01T00:00:00Z