Beta common receptor inactivation attenuates myeloproliferative disease in Nf1 mutant mice

Beta common receptor inactivation attenuates myeloproliferative disease in Nf1 mutant mice

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http://www.wikidata.org/entity/Q35628894
Cul4A is required for hematopoietic cell viability and its deficiency leads to apoptosisMolecular signatures of quiescent, mobilized and leukemia-initiating hematopoietic stem cells.The GM-CSF/IL-3/IL-5 cytokine receptor family: from ligand recognition to initiation of signaling.Lyn- and PLC-beta3-dependent regulation of SHP-1 phosphorylation controls Stat5 activity and myelomonocytic leukemia-like disease.The epigenetic regulator CXXC finger protein 1 is essential for murine hematopoiesis.Deficiency of β Common Receptor Moderately Attenuates the Progression of Myeloproliferative Neoplasm in NrasG12D/+ Mice.Targeting oncogenic Ras signaling in hematologic malignancies.Regulation of myeloproliferation and M2 macrophage programming in mice by Lyn/Hck, SHIP, and Stat5A retroviral mutagenesis screen reveals strong cooperation between Bcl11a overexpression and loss of the Nf1 tumor suppressor gene.Leukemogenic Ptpn11 causes fatal myeloproliferative disorder via cell-autonomous effects on multiple stages of hematopoiesisStat5 is critical for the development and maintenance of myeloproliferative neoplasm initiated by Nf1 deficiencyThe granulocyte-macrophage colony-stimulating factor receptor: linking its structure to cell signaling and its role in disease.Single-cell profiling identifies aberrant STAT5 activation in myeloid malignancies with specific clinical and biologic correlates.Long-term serial xenotransplantation of juvenile myelomonocytic leukemia recapitulates human disease in Rag2-/-γc-/- mice.Normal hematopoiesis and neurofibromin-deficient myeloproliferative disease require Erk.PLC-γ and PI3K link cytokines to ERK activation in hematopoietic cells with normal and oncogenic Kras
P2860

Beta common receptor inactivation attenuates myeloproliferative disease in Nf1 mutant mice

Item
http://www.wikidata.org/entity/Q35628894
description
2006 nî lūn-bûn
@nan
2006年の論文
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2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Beta common receptor inactivat ...... ive disease in Nf1 mutant mice
@ast
Beta common receptor inactivat ...... ive disease in Nf1 mutant mice
@en
type
label
Beta common receptor inactivat ...... ive disease in Nf1 mutant mice
@ast
Beta common receptor inactivat ...... ive disease in Nf1 mutant mice
@en
prefLabel
Beta common receptor inactivat ...... ive disease in Nf1 mutant mice
@ast
Beta common receptor inactivat ...... ive disease in Nf1 mutant mice
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P932
P356
P1433
P1476
Beta common receptor inactivat ...... ive disease in Nf1 mutant mice
@en
P2093
P2860
P304
P31
P356
10.1182/BLOOD-2006-05-025395
P407
P433
P478
P577
P698
P932