Synthetic double-stranded RNA induces innate immune responses similar to a live viral vaccine in humans - Wikidata - wikimedia - TriplyDB

Synthetic double-stranded RNA induces innate immune responses similar to a live viral vaccine in humans

Synthetic double-stranded RNA induces innate immune responses similar to a live viral vaccine in humans

http://www.wikidata.org/entity/Q35669097

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New approaches to understanding the immune response to vaccination and infection Immune response to vaccine adjuvants during the first year of life Hypothesis driven development of new adjuvants: short peptides as immunomodulators Rationale, progress and development of vaccines utilizing STING-activating cyclic dinucleotide adjuvants Early Transcriptional Signatures of the Immune Response to a Live Attenuated Tetravalent Dengue Vaccine Candidate in Non-human Primates Targeting Leishmania major Antigens to Dendritic Cells In Vivo Induces Protective Immunity PolyICLC Exerts Pro- and Anti-HIV Effects on the DC-T Cell Milieu In Vitro and In Vivo Systems analysis of a RIG-I agonist inducing broad spectrum inhibition of virus infectivity Interferons and viruses: an evolutionary arms race of molecular interactions Human genome-wide RNAi screen identifies an essential role for inositol pyrophosphates in Type-I interferon response Influenza vaccines: a moving interdisciplinary field.Systems scale interactive exploration reveals quantitative and qualitative differences in response to influenza and pneumococcal vaccines.Toll-like receptor agonist augments virus-like particle-mediated protection from Ebola virus with transient immune activation.Harnessing Human Cross-Presenting CLEC9A(+)XCR1(+) Dendritic Cells for Immunotherapy.Modulation of innate immune signaling by the secreted form of the West Nile virus NS1 glycoprotein Vaccine strategies utilizing C-type lectin receptors on dendritic cells in vivo Selection of Reference Genes for Gene Expression Studies in Porcine Whole Blood and Peripheral Blood Mononuclear Cells under Polyinosinic:Polycytidylic Acid Stimulation.Combination GITR targeting/PD-1 blockade with vaccination drives robust antigen-specific antitumor immunity.Coadministration of polyinosinic:polycytidylic acid and immunostimulatory complexes modifies antigen processing in dendritic cell subsets and enhances HIV gag-specific T cell immunity.Activated iNKT cells promote memory CD8+ T cell differentiation during viral infection mTORC1-dependent metabolic reprogramming is a prerequisite for NK cell effector function.Intranasal administration of dsRNA analog poly(I:C) induces interferon-α receptor-dependent accumulation of antigen experienced T cells in the airways.Ebolavirus Glycoprotein Fc Fusion Protein Protects Guinea Pigs against Lethal Challenge.TLR4-dependent activation of dendritic cells by an HMGB1-derived peptide adjuvant.Clinical adjuvant combinations stimulate potent B-cell responses in vitro by activating dermal dendritic cells Novel drugs targeting Toll-like receptors for antiviral therapy.Pediatric phase II trials of poly-ICLC in the management of newly diagnosed and recurrent brain tumors.Antigen expression determines adenoviral vaccine potency independent of IFN and STING signaling.Interleukin-1- and type I interferon-dependent enhanced immunogenicity of an NYVAC-HIV-1 Env-Gag-Pol-Nef vaccine vector with dual deletions of type I and type II interferon-binding proteins.Dendritic cell-targeted protein vaccines: a novel approach to induce T-cell immunity Type I IFN Induction via Poly-ICLC Protects Mice against Cryptococcosis.Inactivated Eyedrop Influenza Vaccine Adjuvanted with Poly(I:C) Is Safe and Effective for Inducing Protective Systemic and Mucosal Immunity.Nanoparticulate STING agonists are potent lymph node-targeted vaccine adjuvants.Type I IFN induced by adenovirus serotypes 28 and 35 has multiple effects on T cell immunogenicity TLR3-Induced Maturation of Murine Dendritic Cells Regulates CTL Responses by Modulating PD-L1 Trafficking.Targeting of the non-mutated tumor antigen HER2/neu to mature dendritic cells induces an integrated immune response that protects against breast cancer in mice.Langerhans cells from women with cervical precancerous lesions become functionally responsive against human papillomavirus after activation with stabilized Poly-I:C Human papillomavirus-exposed Langerhans cells are activated by stabilized Poly-I:C.Intranasal treatment with poly(I•C) protects aged mice from lethal respiratory virus infections.TLR3/TICAM-1 signaling in tumor cell RIP3-dependent necroptosis

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Synthetic double-stranded RNA induces innate immune responses similar to a live viral vaccine in humans

http://www.wikidata.org/entity/Q35669097

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2011 nî lūn-bûn

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2011年論文

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name

Synthetic double-stranded RNA ...... a live viral vaccine in humans

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Synthetic double-stranded RNA ...... a live viral vaccine in humans

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Synthetic double-stranded RNA ...... a live viral vaccine in humans

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Synthetic double-stranded RNA ...... a live viral vaccine in humans

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Synthetic double-stranded RNA ...... a live viral vaccine in humans

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Synthetic double-stranded RNA ...... a live viral vaccine in humans

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Journal of Experimental Medicine

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Synthetic double-stranded RNA ...... a live viral vaccine in humans

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P2093

Abdelali Filali-Mouhim

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Andres M Salazar

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Angela Duque-Alarcon

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Annette Nelkenbaum

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Christine Trumpfheller

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Elias K Haddad

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François Lefebvre

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Gaëlle Breton

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Irina Shimeliovich

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Jean-Philippe Goulet

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P2860

Bioconductor: open software development for computational biology and bioinformatics

Unbiased reconstruction of a mammalian transcriptional network mediating pathogen responses

A diverse range of gene products are effectors of the type I interferon antiviral response

Impact of protein kinase PKR in cell biology: from antiviral to antiproliferative action

Synthetic double-stranded RNAs are adjuvants for the induction of T helper 1 and humoral immune responses to human papillomavirus in rhesus macaques

Yellow fever vaccine induces integrated multilineage and polyfunctional immune responses

Linear models and empirical bayes methods for assessing differential expression in microarray experiments

Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

Adjusting batch effects in microarray expression data using empirical Bayes methods

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2357-2366

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10.1084/JEM.20111171

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12

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208

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51779591

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22065672

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3256967

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