The phosphatidylinositol 3-kinase alpha is required for DNA synthesis induced by some, but not all, growth factors.
about
Src-family tyrosine kinases in activation of ERK-1 and p85/p110-phosphatidylinositol 3-kinase by G/CCKB receptorsA natural ErbB4 isoform that does not activate phosphoinositide 3-kinase mediates proliferation but not survival or chemotaxisDirect identification of a major autophosphorylation site on vascular endothelial growth factor receptor Flt-1 that mediates phosphatidylinositol 3'-kinase bindingInteraction of the Flt-1 tyrosine kinase receptor with the p85 subunit of phosphatidylinositol 3-kinase. Mapping of a novel site involved in bindingRequirement of phospholipase C gamma, the tyrosine phosphatase Syp and the adaptor proteins Shc and Nck for PDGF-induced DNA synthesis: evidence for the existence of Ras-dependent and Ras-independent pathwaysActivation of phosphoinositide 3-kinase by interaction with Ras and by point mutationTyrosine kinase signalling in breast cancer: epidermal growth factor receptor and c-Src interactions in breast cancer.A novel pathway for tumor necrosis factor-alpha and ceramide signaling involving sequential activation of tyrosine kinase, p21(ras), and phosphatidylinositol 3-kinasePhosphorylation of tyrosine 503 in the erythropoietin receptor (EpR) is essential for binding the P85 subunit of phosphatidylinositol (PI) 3-kinase and for EpR-associated PI 3-kinase activityDirect association of Grb2 with the p85 subunit of phosphatidylinositol 3-kinaseRegulation of the p85/p110 phosphatidylinositol 3'-kinase: stabilization and inhibition of the p110alpha catalytic subunit by the p85 regulatory subunitEpidermal growth factor-induced phosphatidylinositol 3-kinase activation and DNA synthesis. Identification of Grb2-associated binder 2 as the major mediator in rat hepatocytesA specific role of phosphatidylinositol 3-kinase gamma. A regulation of autonomic Ca(2)+ oscillations in cardiac cellsSlap negatively regulates Src mitogenic function but does not revert Src-induced cell morphology changes.Insulin receptor substrate 1 binds two novel splice variants of the regulatory subunit of phosphatidylinositol 3-kinase in muscle and brain.Phosphatidylinositol 3-kinase is required for integrin-stimulated AKT and Raf-1/mitogen-activated protein kinase pathway activation.Phosphatidylinositol 3-kinase activity is required for the expression of glial fibrillary acidic protein upon cAMP-dependent induction of differentiation in rat C6 glioma.PTEN/MMAC1/TEP1 suppresses the tumorigenicity and induces G1 cell cycle arrest in human glioblastoma cellsA function for phosphatidylinositol 3-kinase beta (p85alpha-p110beta) in fibroblasts during mitogenesis: requirement for insulin- and lysophosphatidic acid-mediated signal transduction.Oncogene activation induces metabolic transformation resulting in insulin-independence in human breast cancer cells.Insulin/IGF-1 and ROS signaling pathway cross-talk in aging and longevity determinationA critical role for phosphoinositide 3-kinase upstream of Gab1 and SHP2 in the activation of ras and mitogen-activated protein kinases by epidermal growth factor.Retrovirus-induced ovine pulmonary adenocarcinoma, an animal model for lung cancer.Both src-dependent and -independent mechanisms mediate phosphatidylinositol 3-kinase regulation of colony-stimulating factor 1-activated mitogen-activated protein kinases in myeloid progenitors.Phosphatidylinositol 3-kinases in tumor progression.Growth factor-dependent signaling and cell cycle progression.PI3K: from the bench to the clinic and back.The phosphatidylinositol-3-kinase inhibitor PX-866 overcomes resistance to the epidermal growth factor receptor inhibitor gefitinib in A-549 human non-small cell lung cancer xenograftsThe many forks in FOXO's road.Fermented soshiho-tang with Lactobacillus plantarum enhances the antiproliferative activity in vascular smooth muscle cell.SRF-dependent gene expression is required for PI3-kinase-regulated cell proliferation.JAK/STAT, Raf/MEK/ERK, PI3K/Akt and BCR-ABL in cell cycle progression and leukemogenesis.Distinct roles for the p110alpha and hVPS34 phosphatidylinositol 3'-kinases in vesicular trafficking, regulation of the actin cytoskeleton, and mitogenesis.The priming/completion paradigm to explain growth factor-dependent cell cycle progression.Mitogenic signal transduction pathways in meningiomas: novel targets for meningioma chemotherapy?The GTPase-activating protein of Ras suppresses platelet-derived growth factor beta receptor signaling by silencing phospholipase C-gamma 1Platelet-derived growth factor-dependent activation of phosphatidylinositol 3-kinase is regulated by receptor binding of SH2-domain-containing proteins which influence Ras activitySpecific activation of p85-p110 phosphatidylinositol 3'-kinase stimulates DNA synthesis by ras- and p70 S6 kinase-dependent pathways.p110δ PI3 kinase pathway: emerging roles in cancer.Phosphoinositide 3-kinase signalling in lung disease: leucocytes and beyond.
P2860
Q22010243-48EA1918-A616-4C85-93B2-7899BD057FBBQ22253346-DE7BD197-E171-49DB-8142-251129665F56Q24291582-3766AFB2-1B4D-4CF1-A9D1-1280E3B68FB1Q24336437-112F7281-CD5F-4636-BB60-905A83C8377AQ24562022-68C359FD-EBD4-4166-ACFD-306615F1BB50Q24563004-2716D765-7588-48CF-A8DF-69F8FA070AE9Q24803054-D65E1B5D-4A05-436B-B5FB-5A710D1A20ABQ28142088-525FEFA4-51D0-4459-B72D-C19690D7A5FAQ28289418-DBBC859F-1378-4BE8-9F71-20E493A4C39EQ28302000-37E50AE3-8564-4D8D-B367-841C36E22FF2Q28379354-E605847C-9C98-43C5-9709-C95690ECA9CDQ28571849-0AE48D28-BE4C-4EC8-A57C-A543E950125AQ28573309-C1360897-3CD7-40A1-B42E-6D55E8C688D8Q30175148-32663F37-A6FC-4FB2-9724-C09E3D54C1ABQ30176985-FAA13A5F-8E1E-40AA-8D1A-0024BD3A3BAFQ30452661-7EF661DA-6062-4258-AA32-E8A735C122F6Q30981432-CBBE1317-B515-4073-BA55-EEB6C0E23A16Q33586807-12578CA6-8158-474E-9FCF-AB1079ECD40CQ33781691-69FA25C7-FD4D-42B5-BC58-8B8E35F8A68AQ33855516-95B70F38-EA64-46B0-9C04-CE2A042BC035Q33865202-D0C58F7F-E9AD-434D-BEB3-EAEBFCD0AA8EQ33929512-7A8E455A-1845-4548-A40C-C513A1A30FE1Q33955907-471A45B7-9875-4AFE-8AB3-9E87D7B78480Q33965534-49EE7AB9-AA91-498E-B882-8D50B9AC0CF1Q34135631-6B58E912-ECD4-4A06-8FB4-D1E6D979EBA2Q34164593-6F39436A-B587-44CA-A6F4-B7C2C9329679Q34195495-CF2FBF45-BBEB-419A-B565-D73995F48D61Q34524510-17D5B9F1-C05D-42C5-8884-120CDEEDCDAFQ35079447-EF76B85D-8FC4-485B-9CE8-7E7A67BF5B9CQ35104697-A4AA9A92-1DA5-4A3B-9B88-960F93C99271Q35123848-B32C8642-2EF0-4FDA-8C01-E4E6FDD0BFA6Q35635353-AF454867-D079-44D4-BAE1-B8BFFDCB9A93Q36255998-0EA45EAC-E3E1-4311-9C0F-9F33F8C5DD2DQ36294480-247EFEDC-A599-4688-8DF4-FD2E0E14628AQ36327729-7C30BFC6-F814-435E-B657-7EE4216B93A6Q36551325-C325256B-EF97-493B-8211-5949AFECF5EEQ36563209-9F6065E8-4CC3-4F29-A934-113090B19563Q36564768-3C209AB5-E048-485A-9B86-AD86DDF5A3FEQ36647928-D73771FC-914E-454A-A2BA-F297F15E3541Q36872061-F9925E51-678A-4C69-AE05-02113C555ED9
P2860
The phosphatidylinositol 3-kinase alpha is required for DNA synthesis induced by some, but not all, growth factors.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
The phosphatidylinositol 3-kin ...... , but not all, growth factors.
@ast
The phosphatidylinositol 3-kin ...... , but not all, growth factors.
@en
type
label
The phosphatidylinositol 3-kin ...... , but not all, growth factors.
@ast
The phosphatidylinositol 3-kin ...... , but not all, growth factors.
@en
prefLabel
The phosphatidylinositol 3-kin ...... , but not all, growth factors.
@ast
The phosphatidylinositol 3-kin ...... , but not all, growth factors.
@en
P2093
P2860
P356
P1476
The phosphatidylinositol 3-kin ...... , but not all, growth factors.
@en
P2093
P2860
P304
P356
10.1073/PNAS.91.19.9185
P407
P577
1994-09-01T00:00:00Z